anti-Porc NOTCH4 anticorps pour Western Blotting

Recommended NOTCH4 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Notch 4 (NOTCH4) Anticorps
  • INT3
  • NOTCH3
  • Int-3
  • Int3
  • N4
  • Notch4
  • notch 4
  • neurogenic locus notch homolog protein 4
  • NOTCH4
  • Notch4
  • LOC100712850
Épitope
Middle Region
22
4
4
4
3
3
3
2
2
2
1
1
1
1
1
1
1
1
Reactivité
Boeuf (Vache), Cobaye, Cheval, Humain, Porc, Rat (Rattus)
70
29
13
6
5
4
4
3
3
1
Hôte
Lapin
58
11
9
6
2
Clonalité
Polyclonal
Conjugué
Cet anticorp NOTCH4 est non-conjugé
4
2
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
56
40
24
15
8
8
8
4
2
2
1
1
Options
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N° du produit (Fournisseur)
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N° du produit ABIN2777550
$ 289.00
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
3.0809376 ABIN2779440 IHC WB Rabbit Middle Region Connectez-vous pour afficher Polyclonal 1
1 ABIN462184 IHC IHC (p) WB Rabbit IgG AA 371-420 Connectez-vous pour afficher Polyclonal 0

General

Antigène Notch 4 (NOTCH4) Anticorps
Épitope Middle Region
(22), (4), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Boeuf (Vache), Cobaye, Cheval, Humain, Porc, Rat (Rattus)
(70), (29), (13), (6), (5), (4), (4), (3), (3), (1)
Hôte Lapin
(58), (11), (9), (6), (2)
Clonalité
Polyclonal
Conjugué Cet anticorp NOTCH4 est non-conjugé
(4), (2), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(56), (40), (24), (15), (8), (8), (8), (4), (2), (2), (1), (1)
Pubmed 3 références disponible
Fournisseur Connectez-vous pour afficher

Détail du produit anti-NOTCH4 anticorps

Détail du antigène NOTCH4 Information d'application Stockage References for anti-NOTCH4 antibody (ABIN2777550) Images
Blocking Peptide Blocking peptide for this product available: ABIN980812
Séquence LLLGLGAARE LRDQAGLAPA DVAHQRNHWD LLTLLEGAGP PEARHKATPG
Homologie Cow: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Pig: 100%, Rat: 93%
Attributs du produit This is a rabbit polyclonal antibody against NOTCH4. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogène The immunogen is a synthetic peptide directed towards the middle region of human NOTCH4
Plasmids, Primers & others

Détail du antigène NOTCH4

Détail du produit anti-NOTCH4 anticorps Information d'application Stockage References for anti-NOTCH4 antibody (ABIN2777550) Images Haut de la page
Antigène
Autre désignation NOTCH4 (NOTCH4 Antibody Extrait)
Sujet NOTCH4 is a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. NOTCH4 is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. NOTCH4 functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. NOTCH4 gene may be associated with susceptibility to schizophrenia in a small portion of cases.
Alias Symbols: INT3, NOTCH4
Protein Interaction Partner: EGFL7, Dlg4, SMAD4, SMAD3, SMAD2, TCEB1, UBC, TP53, MDM2, MAML3, MAML2, FBXW7, MAML1, DLL4, PSEN2, NOTCH4, RBPJ, PSEN1,
Protein Size: 589
Poids moléculaire 61 kDa
ID gène 4855
Pathways Signalisation Notch

Information d'application

Détail du produit anti-NOTCH4 anticorps Détail du antigène NOTCH4 Stockage References for anti-NOTCH4 antibody (ABIN2777550) Images Haut de la page
Indications d'application Optimal working dilutions should be determined experimentally by the investigator.
Commentaires

Antigen size: 589 AA

Restrictions For Research Use only

Stockage

Détail du produit anti-NOTCH4 anticorps Détail du antigène NOTCH4 Information d'application References for anti-NOTCH4 antibody (ABIN2777550) Images Haut de la page
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freeze-thaw cycles.
Stock -20 °C
Stockage commentaire For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-NOTCH4 antibody (ABIN2777550)

Détail du produit anti-NOTCH4 anticorps Détail du antigène NOTCH4 Information d'application Stockage Images Haut de la page
Produit citée dans:

Bhat, Sun, Weger, Raouf: "Notch-Induced Expression of FZD7 Requires Noncanonical NOTCH3 Signaling in Human Breast Epithelial Cells." dans: Stem cells and development, Vol. 25, Issue 7, pp. 522-9, 2016

Sun, Klauzinska, Lake, Lee, Santopietro, Raafat, Salomon, Callahan, Artavanis-Tsakonas: "Trp53 regulates Notch 4 signaling through Mdm2." dans: Journal of cell science, Vol. 124, Issue Pt 7, pp. 1067-76, 2011

Sugaya, Sasanuma, Nohata, Kimura, Fukagawa, Nakamura, Ando, Inoko, Ikemura, Mita: "Gene organization of human NOTCH4 and (CTG)n polymorphism in this human counterpart gene of mouse proto-oncogene Int3." dans: Gene, Vol. 189, Issue 2, pp. 235-44, 1997

Images

Détail du produit anti-NOTCH4 anticorps Détail du antigène NOTCH4 Information d'application Stockage References for anti-NOTCH4 antibody (ABIN2777550) Haut de la page
Images (Fournisseur)
Western Blotting (WB) image for anti-Notch 4 (NOTCH4) (Middle Region) antibody (ABIN2777550) WB Suggested Anti-NOTCH4 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Po...
Immunohistochemistry (IHC) image for anti-Notch 4 (NOTCH4) (Middle Region) antibody (ABIN2777550) Immunohistochemistry with Human Breast tissue at an antibody concentration of 5.0ug/m...
Immunohistochemistry (IHC) image for anti-Notch 4 (NOTCH4) (Middle Region) antibody (ABIN2777550) Immunohistochemistry with Human Breast tissue at an Antibody concentration of 5.0 µg/...
Western Blotting (WB) image for anti-Notch 4 (NOTCH4) (Middle Region) antibody (ABIN2777550) Host: Rabbit Target Name: NOTCH4 Sample Tissue: Human Lung Tumor Antibody Dilut...