anti-CHEK2 Anticorps

522 Checkpoint Kinase 2 (CHEK2) Anticorps de 30 fabricants sont disponibles sur www.anticorps-enligne.fr.

Qualité de données
  • 11
  • 167
Type
  • 522
    Primaire
Antigène
  • 522
Réactivité
  • 511
  • 227
  • 223
  • 26
  • 16
Application
  • 383
  • 147
  • 146
  • 86
  • 74
Hote
  • 439
  • 74
  • 7
  • 1
  • 1
Clonalité
  • 439
  • 83
Clone
  • 7
  • 6
  • 4
  • 3
  • 3
Epitope
  • 57
  • 48
  • 45
  • 32
  • 26
Conjugué
  • 365
  • 18
  • 14
  • 14
  • 14
Isotype
  • 267
  • 28
  • 15
  • 14
  • 8
Format
  • 342
  • 17
Suggested next Filters
522 Produits
ReactivitéHumain
Application IF, IHC, IP, WB
Détails de la commande Cat. No. ABIN6138520
$393.25
Plus shipping costs $45.00
Envoi sous 13 à 14 jours ouvrables
ReactivitéHumain, Souris, Rat (Rattus)
Application ICC, IF, IHC, IP, WB
Détails de la commande Cat. No. ABIN1871829
$368.95
100 μL
Plus shipping costs $45.00
Envoi sous 11 à 13 jours ouvrables
ReactivitéHumain, Souris, Rat (Rattus)
Application ELISA, ICC, IF, IHC, WB
Détails de la commande Cat. No. ABIN6256554
$390.77
Plus shipping costs $45.00
Envoi sous 11 à 12 jours ouvrables
ReactivitéHumain, Souris, Rat (Rattus)
Application ELISA, ICC, IF, IHC, WB
Détails de la commande Cat. No. ABIN6256552
$390.77
Plus shipping costs $45.00
Envoi sous 11 à 12 jours ouvrables
ReactivitéHumain, Souris, Rat (Rattus)
Application ELISA, ICC, IF, IHC, WB
Détails de la commande Cat. No. ABIN6255391
$390.77
Plus shipping costs $45.00
Envoi sous 11 à 12 jours ouvrables
ReactivitéHumain, Souris, Rat (Rattus)
Application ELISA, ICC, IF, IHC, WB
Détails de la commande Cat. No. ABIN6256592
$390.77
Plus shipping costs $45.00
Envoi sous 11 à 12 jours ouvrables
ReactivitéHumain
Application IP, WB
Détails de la commande Cat. No. ABIN950070
$425.71
100 μL
Plus shipping costs $45.00
Envoi sous 11 à 12 jours ouvrables
ReactivitéHumain
Application WB
Détails de la commande Cat. No. ABIN524631
$425.71
100 μg
Plus shipping costs $45.00
Envoi sous 11 à 12 jours ouvrables
Mouse, Monoclonal (4B7), IgG2a kappa
ReactivitéHumain
Application IF, IHC (p), ELISA, WB
Détails de la commande Cat. No. ABIN564867
$440.00
100 μg
Plus shipping costs $45.00
Envoi sous 11 à 12 jours ouvrables
ReactivitéHumain, Souris
Application ELISA, ICC, IF, IHC, WB
Détails de la commande Cat. No. ABIN6271230
$450.00
Plus shipping costs $45.00
Envoi sous 11 à 12 jours ouvrables
Mouse, Monoclonal (10G7), IgG1
ReactivitéChien, Humain, Singe
Application FACS, IF, IHC, IHC (p), WB
Détails de la commande Cat. No. ABIN1497495
$522.50
100 μL
Plus shipping costs $45.00
Envoi sous 11 à 14 jours ouvrables
Mouse, Monoclonal (5C4), IgG1
ReactivitéChien, Humain
Application FACS, IF, IHC, IHC (p), IP, WB
Détails de la commande Cat. No. ABIN1497496
$522.50
100 μL
Plus shipping costs $45.00
Envoi sous 11 à 14 jours ouvrables
Mouse, Monoclonal (2H5), IgG2b
ReactivitéChien, Humain
Application FACS, IHC, IHC (p), IP, WB
Détails de la commande Cat. No. ABIN1497497
$522.50
100 μL
Plus shipping costs $45.00
Envoi sous 11 à 14 jours ouvrables
Mouse, Monoclonal (4C10), IgG2b
ReactivitéChien, Humain
Application FACS, IHC, IHC (p), IP, WB
Détails de la commande Cat. No. ABIN1497498
$522.50
100 μL
Plus shipping costs $45.00
Envoi sous 11 à 14 jours ouvrables
Mouse, Monoclonal (5C7), IgG1
ReactivitéChien, Humain
Application FACS, IHC, IHC (p), IP, WB
Détails de la commande Cat. No. ABIN1497499
$522.50
100 μL
Plus shipping costs $45.00
Envoi sous 11 à 14 jours ouvrables
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CHEK2 profil antigène

Profil protéine

In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the encoded protein is known to inhibit CDC25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1. In addition, this protein interacts with and phosphorylates BRCA1, allowing BRCA1 to restore survival after DNA damage. Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53. Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors. This nuclear protein is a member of the CDS1 subfamily of serine/threonine protein kinases. Several transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with CHEK2

  • checkpoint kinase 2 (CHEK2) anticorps
  • checkpoint kinase 2 (chek2) anticorps
  • checkpoint kinase 2 (Chek2) anticorps
  • serine/threonine-protein kinase chk2 (MCYG_07308) anticorps
  • checkpoint kinase 2 L homeolog (chek2.L) anticorps
  • cds1 anticorps
  • chek2 anticorps
  • chk2 anticorps
  • fa66f08 anticorps
  • hCds1 anticorps
  • hucds1 anticorps
  • lfs2 anticorps
  • pp1425 anticorps
  • rad53 anticorps
  • wu:fa66f08 anticorps
  • zgc:55865 anticorps

Protein level used designations for CHEK2

CHK2 checkpoint homolog , cds1 homolog , checkpoint-like protein CHK2 , serine/threonine-protein kinase Chk2 , protein kinase CHK2 , checkpoint and tumor suppressor protein 2 , Cds1 homolog , Rad53 homolog , protein kinase Chk2 , CHK2 checkpoint homolog (S. pombe) , serine/threonine-protein kinase Chk2-like , serine/threonine-protein kinase chk2 , checkpoint kinase 2 L homeolog , protein kinase Cds1

GENE ID SPECIES
11200 Homo sapiens
486338 Canis lupus familiaris
458733 Pan troglodytes
100192447 Sus scrofa
336998 Danio rerio
768913 Gallus gallus
50883 Mus musculus
114212 Rattus norvegicus
100059288 Equus caballus
100404949 Callithrix jacchus
100467146 Ailuropoda melanoleuca
100594542 Nomascus leucogenys
9226831 Arthroderma otae CBS 113480
398179 Xenopus laevis
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