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anti-Human PAG1 Anticorps:
anti-Rat (Rattus) PAG1 Anticorps:
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Human Monoclonal PAG1 Primary Antibody pour FACS, IHC (p) - ABIN94272
Yerly, Ding, Tauzin, van Echten-Deckert, Borisch, Hoessli: The sphingolipid-rich rafts of ALK+ lymphomas downregulate the Lyn-Cbp/PAG signalosome. dans European journal of haematology 2010
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Human Monoclonal PAG1 Primary Antibody pour IHC (p), IP - ABIN94270
Baumgartner, Angelisová, Setterblad, Mooney, Werling, Horejsí, Langsley: Constitutive exclusion of Csk from Hck-positive membrane microdomains permits Src kinase-dependent proliferation of Theileria-transformed B lymphocytes. dans Blood 2003
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Cow (Bovine) Monoclonal PAG1 Primary Antibody pour IHC (p), IP - ABIN269119
Yamashita, Chattopadhyay, Fensterl, Zhang, Sen: A TRIF-independent branch of TLR3 signaling. dans Journal of immunology (Baltimore, Md. : 1950) 2012
Our study highlights the underlying mechanism of cross interaction between ASCs and breast cancer cells, and indicates that PAG1/Cbp in breast cancer cell may modulate tumor progression and acquired chemoresistance in the ASCs-associated breast cancer microenvironment through Src (Montrer SRC Anticorps) and AKT (Montrer AKT1 Anticorps)/mTOR (Montrer FRAP1 Anticorps) pathways.
Up-regulated expression of CBP (Montrer CREBBP Anticorps) in Jurkat cells could reduce cell homogeneity and promote cell apoptosis
No association Pag1 mutation with patient with Schizophrenia.
The risk-associated allele of rs2370615 predisposes to allergic disease by increasing PAG1 expression, which might promote B cell activation (Montrer BLNK Anticorps) and have a pro-inflammatory effect.
CBP (Montrer CREBBP Anticorps) may decrease the metastasis of esophageal carcinoma by inhibiting the activation of Src (Montrer SRC Anticorps).
The inhibitory function of novobiocin in disrupting the HIF1alpha (Montrer HIF1A Anticorps)/p300 (Montrer EP300 Anticorps) complex might be important in tumor cell growth.
siRNA directed against PAG1 in a radioresistant (Hep-2max) cell line dramatically enhanced the radiosensitivity and IR-induced cell death.
expression of CBP (Montrer CREBBP Anticorps) gene is decreased in esophageal carcinoma, which might contribute to the tumorigenesis and progression.
An over-expression of PAG1 in PC-3M-1E8 cells effectively suppresses the activation of Ras and ERK (Montrer EPHB2 Anticorps), as well as the cyclin D1 (Montrer CCND1 Anticorps) expression, leading to an inhibition of the proliferation ability of tumor cells.
Cbp (Montrer CREBBP Anticorps) down-regulation is primarily mediated by epigenetic histone modifications via oncogenic MAPK (Montrer MAPK1 Anticorps)/PI3K (Montrer PIK3CA Anticorps) pathways in a subset of cancer cells.
Inducible knockdown of PAPP-A (Montrer PAPPA Anticorps) gene expression in adult female mice extends life span.
Intrinsic mitochondrial oxidative capacity was significantly increased in skeletal muscle of aged PAPP-A (Montrer PAPPA Anticorps) KO compared to WT mice. Moreover, 18-month-old PAPP-A (Montrer PAPPA Anticorps) KO mice exhibited significantly enhanced endurance running on a treadmill. Thus, PAPP-A (Montrer PAPPA Anticorps) deficiency in mice is associated with indices of healthy skeletal muscle function with age.
our findings illustrate that Cbp (Montrer CREBBP Anticorps) is an important regulator of Csk (Montrer CSK Anticorps) recruitment to the SFK Lyn (Montrer LYN Anticorps) in Eporesponsive erythroid cells.
Snell, GHKRO, and PAPPA (Montrer PAPPA Anticorps)-KO mice express high levels of two proteins involved in DNA repair, O-6-methylguanine-DNA methyltransferase (MGMT (Montrer MGMT Anticorps)) and N-myc downstream-regulated gene 1 (NDRG1 (Montrer NDRG1 Anticorps)).
STC2 (Montrer STC2 Anticorps) is involved in regulating PAPP-A (Montrer PAPPA Anticorps) activity during the development of atherosclerosis
Study demonstrates proof-of-principle and provides feasibility for a novel therapeutic strategy to inhibit atherosclerotic plaque burden by selective targeting of PAPP-A (Montrer PAPPA Anticorps).
stimulation of PAPP-A (Montrer PAPPA Anticorps) expression by intermittent PTH (Montrer PTH Anticorps) treatment contributes to PTH (Montrer PTH Anticorps) bone anabolism in mice
PAPP-A (Montrer PAPPA Anticorps) affects fascicle structure, thereby affecting tendon phenotype.
This study demonstrated that cbp (Montrer CREBBP Anticorps) increase in skeletal muscle in muscle atrophy.
PAG is constitutively phosphorylated in resting T cells and rapidly dephosphorylated once the TCR is engaged.
The protein encoded by this gene is a type III transmembrane adaptor protein that binds to the tyrosine kinase csk protein. It is thought to be involved in the regulation of T cell activation.
phosphoprotein associated with glycosphingolipid microdomains 1
, phosphoprotein associated with glycosphingolipid-enriched microdomains 1-like
, Csk-binding protein
, phosphoprotein associated with glycosphingolipid-enriched microdomains 1
, transmembrane adapter protein PAG
, transmembrane adaptor protein PAG
, transmembrane phosphoprotein Cbp
, Csk binding protein
, csk-binding protein
, phosphoprotein transmembrane adaptor 1
, phosphoprotein-associated with GEMs
, IGF-dependent IGFBP-4 protease
, insulin-like growth factor-dependent IGF-binding protein 4 protease