anti-PIDD Anticorps

Profil protéine

The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with PIDD

• p53 induced death domain protein 1 (Pidd1) anticorps
• p53-induced death domain protein 1 (PIDD1) anticorps
• p53-induced death domain protein 1 (Pidd1) anticorps

• 1200011D09Rik anticorps
• AU042446 anticorps
• Lrdd anticorps
• Pidd anticorps

Protein level used designations for PIDD

leucine-rich repeat and death domain-containing protein , p53 protein induced, with death domain , p53-induced protein with a death domain , leucine-rich repeats and death domain containing