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anti-Human FOXO1 Anticorps:
anti-Rat (Rattus) FOXO1 Anticorps:
anti-Mouse (Murine) FOXO1 Anticorps:
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Human Polyclonal FOXO1 Primary Antibody pour ICC, IF - ABIN250693
Hoekstra, Sefton, Berry, Lu, Hardt, Marsh, Yin, Clardy, Chakravarti, Bulun, Kim: Progestins activate the AKT pathway in leiomyoma cells and promote survival. dans The Journal of clinical endocrinology and metabolism 2009
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Human Polyclonal FOXO1 Primary Antibody pour IHC - ABIN966149
Zhao, Gan, Pan, Kan, Majeski, Adam, Unterman: Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms. dans The Biochemical journal 2004
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Human Polyclonal FOXO1 Primary Antibody pour IF, IHC - ABIN362088
Zhan, Wang, Li, Xu, Sun, Xu: Activation of Akt/FoxO signaling pathway contributes to induction of neuroprotection against transient global cerebral ischemia by hypoxic pre-conditioning in adult rats. dans Journal of neurochemistry 2010
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Human Polyclonal FOXO1 Primary Antibody pour IHC (fro), IF - ABIN4948288
Sajan, Ivey, Lee, Mastorides, Jurczak, Samuels, Shulman, Braun, Leitges, Farese: PKC? haploinsufficiency prevents diabetes by a mechanism involving alterations in hepatic enzymes. dans Molecular endocrinology (Baltimore, Md.) 2014
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Human Polyclonal FOXO1 Primary Antibody pour IHC - ABIN966148
Gan, Zheng, Chabot, Unterman, Quirion: Nuclear/cytoplasmic shuttling of the transcription factor FoxO1 is regulated by neurotrophic factors. dans Journal of neurochemistry 2005
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Human Monoclonal FOXO1 Primary Antibody pour ICC, IHC - ABIN969521
Lau, Koty, Nalbantoglu: Differential response of glioma cells to FOXO1-directed therapy. dans Cancer research 2009
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Human Polyclonal FOXO1 Primary Antibody pour ICC, IF - ABIN4312363
Sahu, Laakso, Ovaska, Mirtti, Lundin, Rannikko, Sankila, Turunen, Lundin, Konsti, Vesterinen, Nordling, Kallioniemi, Hautaniemi, Jänne: Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer. dans The EMBO journal 2011
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Human Polyclonal FOXO1 Primary Antibody pour ICC, IF - ABIN257291
Haapalainen, Karjalainen, Daddali, Ohlmeier, Anttonen, Määttä, Salminen, Mahlman, Bergmann, Mäkikallio, Ojaniemi, Hallman, Rämet: Expression of CPPED1 in human trophoblasts is associated with timing of term birth. dans Journal of cellular and molecular medicine 1970
Human FOXO1 Primary Antibody pour IHC - ABIN966146
Smith, Norton, Gorospe, Jiang, Nemoto, Holbrook, Finkel, Kusiak: Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity. dans The Journal of cell biology 2005
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Human Polyclonal FOXO1 Primary Antibody pour IF (p), IHC (p) - ABIN684748
Li, Qiu, Liu, Wang, Hu, Gan, Wang: Long-term thermal manipulation in the late incubation period can inhibit breast muscle development by activating endoplasmic reticulum stress in duck (Anasplatyrhynchos domestica). dans Journal of thermal biology 2017
LncRNA DANCR could inhibit osteoblast differentiation by regulating FOXO1 expression.
A significant correlation between the physical activity level and peripheral blood mononuclear cell SIRT1 (Montrer SIRT1 Anticorps) and FOXO1 mRNA expression was found in COPD (Montrer ARCN1 Anticorps) patients.
results indicate that FOXO1 inhibits gastric cancer (GC) growth and angiogenesis under hypoxic conditions via inactivation of the HIF-1alpha (Montrer HIF1A Anticorps)-VEGF (Montrer VEGFA Anticorps) pathway, possibly in association with SIRT1 (Montrer SIRT1 Anticorps); thus, development of treatment modalities aiming at this pathway might be useful for treating GC
These results suggest that liraglutide may exert a renoprotective effect by a FoxO1-mediated upregulation of renal MnSOD (Montrer SOD2 Anticorps) expression in the early DKD.
FOXO1, acetylation of FOXO1 and the following interaction between Ac-FOXO1 and Atg7 regulated the basal and serum starvation induced autophagy as evidenced by light chain 3 (LC3) accumulation and p62 degration.
PAX3 (Montrer PAX3 Anticorps)-FOXO1 fusion protein serves as a driver mutation to initiate a cascade of mRNA and miRNA changes that ultimately reprogram proliferating myoblasts to induce the formation of alveolar rhabdomyosarcoma
Induced the nuclear accumulation of FOXO1.
The data indicate that Akt2 (Montrer AKT2 Anticorps) ablation protects against cardiac aging through restored Foxo1-related autophagy and mitochondrial integrity.
the present study demonstrated that the expression of miR (Montrer MLXIP Anticorps)-196a in human liver cancer cells was upregulated; downregulation of miR (Montrer MLXIP Anticorps)-196a regulated human liver cancer cell biological functions which could benefit the clinical therapy of human liver cancer in the future
Inhibition of FOXO1 enhanced angiogenesis in human bio-engineered capillaries, and resulted in microvascular regeneration and improved function in mouse models of injury-repair.
The findings reveal a novel mechanism by which Ca2 (Montrer CA2 Anticorps)+ overload disrupts myofibril integrity by activating a Calcineurin-FoxO (Montrer FOXO3 Anticorps)-MuRF1 (Montrer TRIM63 Anticorps)-proteosome signaling pathway.
These results indicate that miR (Montrer MYLIP Anticorps)-182 functions as a FoxO1 inhibitor to antagonize osteoblast proliferation and differentiation, with a subsequent negative effect on osteogenesis.
gas6 (Montrer GAS6 Anticorps) protects endothelial cells from apoptosis by a mechanism that involves PI3K-Akt (Montrer AKT1 Anticorps)-dependent inactivation of FOXO1a.
Chimeric antigen receptor T cells releasing IL-18 (Montrer IL18 Anticorps) convert to T-Bet(high) FoxO1(low) effectors that exhibit augmented activity against advanced solid tumors.
the molecular level, we confirmed, for the first time, that RES upregulated FoxO1 transcriptional activity by inhibiting the PI3K/AKT (Montrer AKT1 Anticorps) signaling pathway, and hence promoted resistance to oxidative damage and restrained osteoclastogenesis. Inhibition of the PI3K/AKT (Montrer AKT1 Anticorps) signaling pathway may be induced by RANKL (Montrer TNFSF11 Anticorps).
FOXO1 is dispensable for naive T cell expression of TCF7 (Montrer TCF7 Anticorps), it is essential for the expression of TCF7 (Montrer TCF7 Anticorps) in a small subset of T cells within days following primary infection.
Foxo1 expression compromised embryonic stem cell self-renewal
we identified that Sirtuin 1 (SIRT1 (Montrer SIRT1 Anticorps)), a deacetylase that suppresses FoxO1 acetylation in granulosa cell (GCs (Montrer UGCG Anticorps)), was downregulated by miR (Montrer MLXIP Anticorps)-181a and reversed the promoting effects of H2O2 and miR (Montrer MLXIP Anticorps)-181a on FoxO1 acetylation and GC apoptosis.
Study identified the roles of Foxo1 as a positive regulator and Foxp1 as a negative regulator of TH9 cell differentiation and antitumor activity.
miR (Montrer MLXIP Anticorps)-150-mediated suppression of Foxo1 regulates the balance between effector and memory cell differentiation
Authors found that the repress effect of alphaMSH (Montrer POMC Anticorps) in adipocytes apoptosis is acting through Foxo1/mTORC2 (Montrer CRTC2 Anticorps) pathway. These findings indicate that, alphaMSH (Montrer POMC Anticorps) has a strong inhibitory effect on ROS (Montrer ROS1 Anticorps)-induced adipocyte apoptosis and underlying mechanism is interacting with key factors in mTOR (Montrer FRAP1 Anticorps) signal pathway.
Sirt3 (Montrer SIRT3 Anticorps) activation is essential to improve autophagy flux by reducing the acetylation modification on FoxO1, which in turn alleviates myocardial hypertrophy.
he knockdown of FoxO1 repressed lipogenesis by downregulating PDGFRalpha, and miR (Montrer MYLIP Anticorps)-34a inhibited adipogenesis through targeting PDGFRalpha.
These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt (Montrer AKT1 Anticorps)-mTOR (Montrer FRAP1 Anticorps)-FOXO1 signaling and suppressing the activation of TLR4 (Montrer TLR4 Anticorps) and/or NOD2 (Montrer NOD2 Anticorps) signaling pathways.
let-7g induces porcine granulosa cells apoptosis by inhibiting the MAP3K1 (Montrer MAP3K1 Anticorps) gene, which promotes FoxO1 expression and dephosphorylation with nuclear accumulation.
inhibition of FoxO1 expression level caused by miR (Montrer MYLIP Anticorps)-15a/b over-expression had a positive effect on adipogenesis. Thus, we conclude that miR (Montrer MYLIP Anticorps)-15a/b promote adipogenesis in porcine pre-adipocyte via repressing FoxO1
Results show that FoxO1 likely regulates MyHC I (Montrer MYH7 Anticorps) negatively and MyHC IIx and MyHC IIb (Montrer MYH4 Anticorps) positively and may play a pivotal role in the determination of muscle fiber type.
Data suggest forkhead box protein O1 (FoxO1) involvement in the regulation of TNF-related apoptosis-inducing ligand TRAIL (Montrer TNFSF10 Anticorps) and Fas ligand FasL (Montrer FASL Anticorps) expression during follicular atresia.
Data show that IL-4 (Montrer IL4 Anticorps) induces upregulation of the junction protein claudin-5 (Montrer CLDN5 Anticorps) in endothelial cells (ECs) through activation of Jak (Montrer JAK3 Anticorps)/STAT6 (Montrer STAT6 Anticorps) and phosphorylation and translocation of FoxO1 from the nucleus to the cytoplasm.
FoxO1 and C/EBPb (Montrer CEBPB Anticorps) regulate preadipocyte adipogenesis possibly through C/EBPb (Montrer CEBPB Anticorps)-> FoxO1-> C/EBPb (Montrer CEBPB Anticorps) feedback regulatory loop and FoxO1-C/EBPb (Montrer CEBPB Anticorps) protein complex.
FoxO1 delays and negatively regulates the porcine myoblast differentiation. It may also play a critical role in muscle fiber-type specification through the inhibition of myogenic regulation factors.
concluded that PI 3 (Montrer PI3 Anticorps)-kinase and Akt (Montrer AKT1 Anticorps) are activated after renal ischemia/reperfusion and that Akt (Montrer AKT1 Anticorps) phosphorylation leads to phosphorylation of FKHR and FKHRL1 (Montrer FOXO3 Anticorps), which may affect epithelial cell fate in acute renal failure.
This is the first study demonstrating a role for AMPK (Montrer PRKAA1 Anticorps)-SIRT1 (Montrer SIRT1 Anticorps)-FOXO1 signalling pathway in regulating apoptosis in bovine intramuscular adipocytes.
MicroRNA-183-96-182 cluster regulates bovine granulosa cell function by targeting FOXO1 gene.
downregulation of SIRT1 (Montrer SIRT1 Anticorps) and FoxO1 were observed in the backfat tissue of Lilu cattle with increasing age
FOXO (Montrer FOXO3 Anticorps) is a key regulator of ROS (Montrer ROS1 Anticorps)-induced apoptosis in mammalian cells.
Protein kinase A-alpha directly phosphorylates FoxO1 in vascular endothelial cells to regulate expression of vascular cellular adhesion molecule (Montrer NCAM1 Anticorps)-1 mRNA.
The results demonstrate pathways through which two different mediators, TNF-alpha (Montrer TNF Anticorps) and an advanced glycation endproduct, can induce pericyte apoptosis through activation of the transcription factor FOXO1.
FOXO1, 3, and 4 as well as their upstream regulator, AKT/p-AKT (Montrer AKT1 Anticorps), was examined in rhesus macaque ovaries of three developmental stages: fetal, prepubertal, and adult
FoxO1 translocation to the nucleus, and the increase in FoxO1 DNA binding activity in X. laevis liver strongly correlate with the up-regulation of manganese-dependent superoxide dismutase (Montrer SOD1 Anticorps) and catalase (Montrer CAT Anticorps) mRNA and protein levels in this organ.
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined\; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
forkhead box protein O1
, forkhead box protein O1A
, forkhead, Drosophila, homolog of, in rhabdomyosarcoma
, forkhead box O1A
, forkhead box protein O1-A
, fox family transcription factor FoxO1a.1
, foxhead box protein O1-A
, Forkhead box protein O1A
, Forkhead in rhabdomyosarcoma
, forkhead box O1A (rhabdomyosarcoma)
, forkhead box O1a
, forkhead in rhabdomyosarcoma
, forkhead protein 1
, forkhead/winged helix transcription factor FOXO1a
, forkhead box O1
, forkhead box protein O1-like