anti-Chien MLST8 anticorps pour Immunohistochemistry

Recommended MLST8 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
MTOR Associated Protein, LST8 Homolog (S. Cerevisiae) (MLST8) Anticorps
  • gbl
  • lts8
  • GBL
  • GbetaL
  • LST8
  • POP3
  • WAT1
  • 0610033N12Rik
  • AA409454
  • AI505104
  • AI851821
  • Gbl
  • fi37e04
  • wu:fi37e04
  • zgc:55455
  • zgc:85668
  • MTOR associated protein, LST8 homolog L homeolog
  • MTOR associated protein, LST8 homolog
  • MTOR associated protein, LST8 homolog (S. cerevisiae)
  • mlst8.L
  • MLST8
  • Mlst8
  • mlst8
Épitope
AA 150-200
25
14
11
10
9
6
4
3
3
3
2
2
2
2
1
1
Reactivité
Poulet, Chimpanzé, Boeuf (Vache), Chien, Humain, Macaque, Singe, Souris, Rat (Rattus)
117
63
45
9
8
7
4
4
4
3
3
3
3
2
2
2
2
1
1
1
Hôte
Lapin
110
18
2
Clonalité
Polyclonal
Conjugué
Cet anticorp MLST8 est non-conjugé
7
7
6
5
5
5
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
109
44
31
17
13
9
5
3
2
2
2
1
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N° du produit ABIN2470104
$ 550.00
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General

Antigène MTOR Associated Protein, LST8 Homolog (S. Cerevisiae) (MLST8) Anticorps
Épitope AA 150-200
(25), (14), (11), (10), (9), (6), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1)
Reactivité Poulet, Chimpanzé, Boeuf (Vache), Chien, Humain, Macaque, Singe, Souris, Rat (Rattus)
(117), (63), (45), (9), (8), (7), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1)
Hôte Lapin
(110), (18), (2)
Clonalité
Polyclonal
Conjugué Cet anticorp MLST8 est non-conjugé
(7), (7), (6), (5), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(109), (44), (31), (17), (13), (9), (5), (3), (2), (2), (2), (1)
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Détail du produit anti-MLST8 anticorps

Détail du antigène MLST8 Information d'application Stockage Images
Purification Protein G Column
Immunogène GBL antibody was raised against amino acids 150 - 200 of GBL (Human).

Détail du antigène MLST8

Détail du produit anti-MLST8 anticorps Information d'application Stockage Images Haut de la page
Antigène
Autre désignation GBL (MLST8 Antibody Extrait)
Sujet LST8, a 36-40 kDa intracellular protein, is a novel member of WD-40 protein family. It is a highly conserved cytosolic protein consisting of seven WD-40 repeating motifs. LST8 is a functional component of mTOR signaling complex (TORC1) and positively up-regulates the mTOR pathway. It interacts with the kinase domain of mTOR and stabilizes its interaction with raptor. LST8 participates in regulating cell growth and also in nutrient and growth factor-mediated mTOR signaling to S6K1. Reports suggest up-regulated expression of LST8 due to insulin indicating a possible role of LST8 in intracellular events related to insulin-receptor activation including insulin-stimulated glucose transport and glycogen synthesis. Northern Blot analysis detected a ubiquitous expression of LST8 with highest expression in brain and testis. Part of the mammalian target of rapamycin complex 1 (mTORC1), which is composed of mTOR, regulatory associated protein of mTOR (Raptor), mammalian LST8/G-protein beta-subunit like protein (mLST8/GbetaL) and the recently identified partner PRAS40. This complex is characterized by the classic features of mTOR by functioning as a nutrient/energy/redox sensor and controlling protein synthesis. The activity of this complex is stimulated by insulin, growth factors, serum, phosphatidic acid, amino acids (particularly leucine), and oxidative stress.
ID gène 64223
UniProt Q9BVC4
Pathways Signalisation PI3K-Akt, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Autophagy, CXCR4-mediated Signaling Events

Information d'application

Détail du produit anti-MLST8 anticorps Détail du antigène MLST8 Stockage Images Haut de la page
Indications d'application GBL antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 5 μg/mL.
Restrictions For Research Use only

Stockage

Détail du produit anti-MLST8 anticorps Détail du antigène MLST8 Information d'application Images Haut de la page
Format Liquid
Buffer PBS, 0.2 % gelatin, 0.05 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation As with all antibodies avoid freeze/thaw cycles.
Stock 4 °C/-20 °C
Stockage commentaire GBL antibody can be stored short term 4 °C. For long term storage aliquot and store at -20 °C.

Images

Détail du produit anti-MLST8 anticorps Détail du antigène MLST8 Information d'application Stockage Haut de la page
Supplier Images
Immunohistochemistry (IHC) image for anti-MTOR Associated Protein, LST8 Homolog (S. Cerevisiae) (MLST8) (AA 150-200) antibody (ABIN2470104) anti-MTOR Associated Protein, LST8 Homolog (S. Cerevisiae) (MLST8) (AA 150-200) antibody