Profil protéine

The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with PFKFB2

• 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a (pfkfb2a) anticorps
• 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (PFKFB2) anticorps
• 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (pfkfb2) anticorps
• 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (Pfkfb2) anticorps

• 4930568D07Rik anticorps
• PFK-2/FBPase-2 anticorps
• pfkfb2 anticorps
• RH2K anticorps
• zgc:56282 anticorps

Protein level used designations for PFKFB2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 , pfk-2/fbpase-2 , 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2-like , 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 , 6PF-2-K/Fru-2,6-P2ASE heart-type isozyme , 6PF-2-K/Fru-2,6-P2ase 2 , PFK/FBPase 2 , PFKFB, cardiac , fructose-2,6-bisphosphatase, cardiac isozyme , 6PF-2-K/Fru-2,6-P2ase heart-type isozyme , PFK-2/FBPase-2 gene B , 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (heart) , PFK-2/FBPase-2 , fructose 6-phosphate 2-kinase/fructose 2,6-bisphosphatase , 6-phosphofructo-2-kinase /fructose-2,6-bisphosphatase