Use your antibodies-online credentials, if available.
Il n’y a pas de produits dans votre liste de comparaison.
Votre panier est vide.
Afficher toutes les espèces
Afficher tous les synonymes
Sélectionnez vos espèces et l'application
anti-Human AXL Anticorps:
anti-Mouse (Murine) AXL Anticorps:
anti-Rat (Rattus) AXL Anticorps:
Vous arrivez à notre recherche pré-filtrée.
Human Polyclonal AXL Primary Antibody pour BR, CyTOF - ABIN5012837
Gould, Baxi, Schroeder, Peng, Leadley, Peterson, Perrin: Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses. dans Journal of thrombosis and haemostasis : JTH 2005
Show all 31 Pubmed References
Human Polyclonal AXL Primary Antibody pour IHC - ABIN965632
Partanen, Mäkelä, Alitalo, Lehväslaiho, Alitalo: Putative tyrosine kinases expressed in K-562 human leukemia cells. dans Proceedings of the National Academy of Sciences of the United States of America 1991
Show all 7 Pubmed References
Human Polyclonal AXL Primary Antibody pour IHC - ABIN965631
OBryan, Frye, Cogswell, Neubauer, Kitch, Prokop, Espinosa, Le Beau, Earp, Liu: axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase. dans Molecular and cellular biology 1991
Show all 7 Pubmed References
Mouse (Murine) Monoclonal AXL Primary Antibody pour CyTOF, FACS - ABIN4899408
Fujimori, Grabiec, Kaur, Bell, Fujino, Cook, Svedberg, MacDonald, Maciewicz, Singh, Hussell: The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung. dans Mucosal immunology 2015
Show all 4 Pubmed References
Human Monoclonal AXL Primary Antibody pour ELISA, WB - ABIN965629
Rual, Venkatesan, Hao, Hirozane-Kishikawa, Dricot, Li, Berriz, Gibbons, Dreze, Ayivi-Guedehoussou, Klitgord, Simon, Boxem, Milstein, Rosenberg, Goldberg, Zhang, Wong, Franklin, Li, Albala, Lim et al.: Towards a proteome-scale map of the human protein-protein interaction network. ... dans Nature 2005
Show all 3 Pubmed References
Human Monoclonal AXL Primary Antibody pour ELISA, WB - ABIN968973
Budagian, Bulanova, Orinska, Duitman, Brandt, Ludwig, Hartmann, Lemke, Saftig, Bulfone-Paus: Soluble Axl is generated by ADAM10-dependent cleavage and associates with Gas6 in mouse serum. dans Molecular and cellular biology 2005
Show all 2 Pubmed References
Human Monoclonal AXL Primary Antibody pour IF, ELISA - ABIN965630
Green, Ikram, Vyas, Patel, Proby, Ghali, Leigh, OToole, Storey: Overexpression of the Axl tyrosine kinase receptor in cutaneous SCC-derived cell lines and tumours. dans British journal of cancer 2006
Show all 2 Pubmed References
Human Polyclonal AXL Primary Antibody pour IHC, IHC (p) - ABIN4282541
Pinato, Mauri, Lloyd, Vaira, Casadio, Boldorini, Sharma: The expression of Axl receptor tyrosine kinase influences the tumour phenotype and clinical outcome of patients with malignant pleural mesothelioma. dans British journal of cancer 2013
Show all 2 Pubmed References
Human Monoclonal AXL Primary Antibody pour ICC, ELISA - ABIN968974
Vajkoczy, Knyazev, Kunkel, Capelle, Behrndt, von Tengg-Kobligk, Kiessling, Eichelsbacher, Essig, Read, Erber, Ullrich: Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival. dans Proceedings of the National Academy of Sciences of the United States of America 2006
Human Monoclonal AXL Primary Antibody pour RNAi, ELISA - ABIN560017
Ammoun, Provenzano, Zhou, Barczyk, Evans, Hilton, Hafizi, Hanemann: Axl/Gas6/NF?B signalling in schwannoma pathological proliferation, adhesion and survival. dans Oncogene 2014
The role of AXL in the esophageal adenocarcinoma cell invasion through upregulation of extracellular acidification, lysosomes peripheral distribution, and exocytosis.
Decreased ARL2 expression level was clinically correlated to the higher grades and poorer outcomes of glioma patients. ARL2 overexpression attenuated the proliferation, clone formation, migration, invasive and tumorigenic capabilities of glioma cells by regulating the expression of receptor tyrosine kinase AXL.
Axl binds to and phosphorylates TNS2 and that Axl/TNS2/IRS-1 cross-talk may potentially play a critical role in glucose metabolism of cancer cells.
AXL expression is regulated by miR-34a.miR-34a regulates dendritic cells activation by targeting AXL.AXL expression is reduced in rheumatoid arthritis CD1c+ dendritic cells.
Axl induction during viral infections contributes to maintaining macrophage capacity to engulf apoptotic cells, which may have important consequences for resolution of anti-viral immune responses.
Serum soluble AXL is not a helpful biomarker for cardiovascular complications after heart transplantation.
miR-34a is an oncogenic miRNA, downregulated in the distinct breast cancer subtypes. It also targets MET and AXL 3'-UTRs in triple-negative breast cancer.
identify the receptor tyrosine kinase Axl as a novel target of ZNF224 transcriptional repression activity.
Findings suggest that METTL3 plays very important oncogenic roles in ovarian carcinoma development and/or aggressiveness by stimulating AXL translation and EMT.
Co-expression of CDCP1 and AXL is often observed in EGFR-mutation-positive tumors, limiting the efficacy of EGFR TKIs. Co-treatment with EGFR TKI and TPX-0005 warrants testing.
This study demonstrates that motility behavior of AXL-expressing tumor cells can be elicited by Gas6-bearing apoptotic bodies generated from tumor treatment with therapeutics that produce killing of a portion of the tumor cells present but not all, hence generating potentially problematic invasive and metastatic behavior of the surviving tumor cells
Results show that average methylation in AXL at birth was associated with higher risk for asthma-related phenotypes in childhood, especially wheezing. The effects of average AXL methylation on wheezing symptoms were magnified in girls compared to boys.
we identified YAP-driven AXL overexpression as a mechanism of resistance to EGFR TKIs in lung cancer cells.
The anti-angiogenic effect of luteolin may be associated with the inhibition of the Gas6/Axl pathway and its downstream phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) signaling pathways.
AXL is influenced by p53 status and could cause the emergence of aggressive clones after exposure to chemotherapy in colon and breast cancer
Taken together, these findings suggest that AXL most likely serves as an attachment factor for Zika virus on the cell surface, and that productive infection requires endocytosis and delivery of the virus to acidified intracellular compartments.
serum Axl shows high diagnostic accuracy at early stage hepatocellular carcinoma as well as cirrhosis
AXL is the only relevant Zika virus entry cofactor expressed on fetal endothelial cells, and that when produced in mammalian cells, only Zika virus, but not West Nile virus or dengue virus, can use AXL, because it more efficiently binds Gas6.
Results indicate AXL receptor tyrosine kinase (AXL) as an important mediator of docetaxel resistance in prostate cancer.
AXL promotes epithelial cell efferocytosis in a tyrosine kinase-dependent manner.AXL role in AKT-dependent drug resistance.
ALX-deficient macrophages have defective microparticle clearance resulting in lung inflammation and injury.
These results suggest a novel role for Axl in suppressing antigen presentation through MHCI, and enhancing cytokine release, which promotes a suppressive myeloid microenvironment.
AXL is not the key receptor for Zika virus infection using an Axl knockout mouse model.
present findings indicate that MafB enhances efferocytosis by regulating Axl expression in RAW264.7 macrophages
Study found that hematopoietic cell-Axl deficiency in Western-type diet-fed Ldlr(-/-) mice does not affect the progression of advanced atherosclerosis or lesional processes associated with TAM receptor signaling.
This study demonstrated that the Gas6(-/-) Axl(-/-) double knockout (DKO) mice showed axonal damage, motor deficits, prolonged neuroinflammation, and less remyelination following cuprizone exposure.
These results demonstrate that AXL is essential for limiting the immunosuppressive effects of type I interferons and enabling the induction of protective antiviral adaptive immunity.
GAS6-AXL signaling-mediated autophagy induction in murine macrophages ameliorates hepatic inflammatory responses by inhibiting NLRP3 inflammasome activation.
Both Axl+/- and Axl-/- suckling mice supported the replication of Zika virus.
reciprocal activation of Axl and Mer receptor tyrosine kinases has a major impact on the outcome of renal inflammation.
Axl is critical for survival of T lymphocytes, especially during vascular remodeling in hypertension.
Axl, Mertk and Tyro3 receptors are not required for Zika virus entry and infection.
Axl plays an essential role in the regulation of NK cell development as well as natural killer effector function.
Matrix metalloproteases ADAM10 and TACE (ADAM17) cleave AXL receptor tyrosine kinase (Axl) in lupus-prone leukocytes.
Gas6/Axl and Akt/FoxO1a were involved in protective effects of testosterone on VSMCs senescence and collagen synthesis.
Axl allows specific identification of airway macrophages, and that its expression is critical for macrophage functional compartmentalization in the airspaces or lung interstitium.
results establish TAM receptors as both controllers of microglial physiology and potential targets for therapeutic intervention in central nervous system disease
These results suggest that TAM receptors support NSCs survival, proliferation and differentiation by regulating expression of neurotrophins, especially the nerve growth factor.
Gas6-induced Axl signaling is a critical driver of pancreatic cancer progression.
The results indicate that Axl and Mer receptors cooperatively regulate the systemic immune tolerance to male germ cell antigens.
activation of receptor tyrosine kinase Axl inhibits the osteogenic differentiation of vascular pericytes.
The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
, AXL transforming sequence/gene
, tyrosine-protein kinase receptor UFO
, adhesion-related kinase
, ufo oncogene homolog