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Aperçu des produits pour BRK1 Protéines (BRK1)

Full name:: BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit Protéines (BRK1)

Chez www.anticorps-enligne.fr sont 10 BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit (BRK1) Protéines de 5 de différents fournisseurs disponibles. De plus, nous expédions BRK1 Anticorps (30) et BRK1 Kits (4) et beaucoup plus de produits pour cette protéine. Un total de 46 BRK1 produits sont actuellement listés.

Synonymes:: 6720456B07Rik, ATBRK1, AW011779, BRICK1, brk1, C3orf10, C22H3orf10, hHBrk1, HSPC300, MDS027, T9I22.8, T9I22_8

afficher tous les protéines	Gène	GeneID	UniProt
Rat BRK1	BRK1	679934
	BRK1	55845	Q8WUW1
	BRK1	101314	Q91VR8
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BRK1 Protéines (BRK1) par origine

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Pathways pertinentes pour BRK1 Protéines

Signalisation RTK

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Plus protéines pour BRK1 partenaires d'interaction

Human BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit (BRK1) interaction partners

Sp1 transcriptionally regulates BRK1 expression in non-small cell lung cancer cells.
We verified that NRF-1 positively regulates FAM134C and ENOX1, and negatively regulates C3orf10 in human neuroblastoma IMR-32 cells and primary rat cortical neurons.
Data show that Brk1 downregulation results in defective directional migration and invasive growth in renal cell carcinoma cells as well as in other tumor cell types.
Von Hippel-Lindau (VHL) locus deletion of the HSPC300 actin regulator gene greatly lowers risk of clear cell renal cell carcinoma development in Spanish VHL syndrome patients studied.
higher expression in primary lung tumours with lymph node metastases and also in tumours from patients with more advanced disease
Growing body of evidence suggesting that patients with VHL syndrome caused by large VHL deletions that include C3orf10 may be designated as having a specific subtype (Type 1B) of the disorder.

Mouse (Murine) BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit (BRK1) interaction partners

Data show that genetic ablation of Brk1 results in dramatic defects in embryo compaction and development, suggesting an essential role for this protein in actin dynamics.

Arabidopsis thaliana BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit (BRK1) interaction partners

BRK1 is required for accumulation of SCAR1 protein in vivo, potentially explaining the apparently essential role of BRK1 in ARP2/3 complex function
member of the "distorted group" of trichome morphology mutants and a critical WAVE-complex subunit that selectively stabilizes the Arp2/3 activator SCAR2

Profil protéine BRK1

Profil protéine

Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex (By similarity).

Alternative names and synonyms associated with BRK1

BRICK1, SCAR/WAVE actin-nucleating complex subunit (brk1)
BRICK1, SCAR/WAVE actin nucleating complex subunit (BRK1)
BRICK1, SCAR/WAVE actin-nucleating complex subunit (Brk1)
BRICK1, SCAR/WAVE actin nucleating complex subunit (brk1)
brick 1 (brk1)
BRICK1, SCAR/WAVE actin-nucleating complex subunit S homeolog (brk1.S)
BRICK1 (BRK1)

6720456B07Rik Protéine
ATBRK1 Protéine
AW011779 Protéine
BRICK1 Protéine
brk1 Protéine
C3orf10 Protéine
C22H3orf10 Protéine
hHBrk1 Protéine
HSPC300 Protéine
MDS027 Protéine
T9I22.8 Protéine
T9I22_8 Protéine

Protein level used designations for BRK1

probable protein BRICK1 , probable protein brick1 , GRMZM5G842058 , protein BRICK1 , probable protein BRICK1-B , BRICK1, SCAR/WAVE actin-nucleating complex subunit, homolog , haematopoietic stem/progenitor cell protein 300

GENE ID	SPECIES
415187	Danio rerio
540092	Bos taurus
679934	Rattus norvegicus
100528356	Ictalurus punctatus
542086	Zea mays
100037105	Xenopus laevis
55845	Homo sapiens
101314	Mus musculus
816795	Arabidopsis thaliana

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