Profil protéine

Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.

Alternative names and synonyms associated with DDR2

• discoidin domain receptor tyrosine kinase 2 (DDR2) anticorps
• discoidin domain receptor family, member 2 (Ddr2) anticorps
• discoidin domain receptor tyrosine kinase 2 (Ddr2) anticorps
• discoidin domain receptor family, member 2, like (ddr2l) anticorps

• AW495251 anticorps
• ddr2 anticorps
• MIG20a anticorps
• Ntrkr3 anticorps
• si:ch211-193c2.1 anticorps
• Afficher tous les alias de synonymes
• TKT anticorps
• Tyro10 anticorps

Protein level used designations for DDR2

CD167 antigen-like family member B , cell migration-inducing protein 20 , discoidin domain receptor 2 , discoidin domain receptor family, member 2 , discoidin domain-containing receptor 2 , discoidin domain-containing receptor tyrosine kinase 2 , hydroxyaryl-protein kinase , migration-inducing gene 16 protein , neurotrophic tyrosine kinase receptor related 3 , neurotrophic tyrosine kinase, receptor-related 3 , receptor protein-tyrosine kinase TKT , tyrosine-protein kinase TYRO10 , tyrosylprotein kinase , discoidin domain receptor tyrosine kinase 2 , CD167b antigen , tyrosine-protein kinase TYRO 10