anti-Souris EPH Receptor B2 anticorps pour Enzyme Immunoassay

Recommended EPH Receptor B2 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
EPH Receptor B2 (EPHB2) Anticorps
  • CAPB
  • DRT
  • EK5
  • EPHT3
  • ERK
  • Hek5
  • PCBC
  • Tyro5
  • Cek5
  • Drt
  • ETECK
  • Erk
  • Nuk
  • Prkm5
  • Qek5
  • Sek3
  • RGD1564232
  • EPH receptor B2
  • Eph receptor B2
  • EPHB2
  • Ephb2
Épitope
N-Term
25
14
12
12
11
11
8
7
7
6
4
4
3
2
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris
159
50
6
6
4
3
3
3
2
2
1
1
1
1
Hôte
Lapin
91
40
20
18
Clonalité
Polyclonal
Conjugué
Cet anticorp EPH Receptor B2 est non-conjugé
10
7
7
7
7
6
2
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
127
99
61
38
31
29
15
6
3
2
1
1
1
1
1
Fournisseur
Connectez-vous pour afficher
N° du produit (Fournisseur)
Connectez-vous pour afficher
Request

Recevoir ce produit gratuitement

Envoyez-nous votre proposition de validation. J'aimerais valider ce produit

Savoir plus

Images

N° du produit ABIN359812
$ 390.50
Plus shipping costs $45.00

General

Antigène EPH Receptor B2 (EPHB2) Anticorps
Épitope N-Term
(25), (14), (12), (12), (11), (11), (8), (7), (7), (6), (4), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain, Souris
(159), (50), (6), (6), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1)
Hôte Lapin
(91), (40), (20), (18)
Clonalité
Polyclonal
Conjugué Cet anticorp EPH Receptor B2 est non-conjugé
(10), (7), (7), (7), (7), (6), (2), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(127), (99), (61), (38), (31), (29), (15), (6), (3), (2), (1), (1), (1), (1), (1)
Pubmed 5 références disponible
Fournisseur Connectez-vous pour afficher

Détail du produit anti-EPH Receptor B2 anticorps

Détail du antigène EPH Receptor B2 Information d'application Stockage References for anti-EPH Receptor B2 antibody (ABIN359812) Images
Specificité This antibody reacts to EphB2.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogène This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between aa 111 - 140 from the N-terminal region of human EphB2.
Isotype Ig Fraction
Plasmids, Primers & others

Détail du antigène EPH Receptor B2

Détail du produit anti-EPH Receptor B2 anticorps Information d'application Stockage References for anti-EPH Receptor B2 antibody (ABIN359812) Images Haut de la page
Antigène
Autre désignation EPHB2 (EPHB2 Antibody Extrait)
Sujet Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ligand-activated form of EphB2, which belongs to the Tyr family of protein kinases, interacts with multiple proteins, including GTPase-activating protein (RASGAP) through its SH2 domain. It binds RASGAP through the juxtamembrane tyrosines residues, and also interacts with PRKCABP and GRIP1 This type I membrane protein is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressed in fetal brain. This protein contains putatively 2 fibronectin type III domains and 1 sterile alpha motif (SAM) domain.Synonyms: DRT, DRT, EPHT3, EPTH3, ERK, Ephrin type-B receptor 2, HEK5, NY-REN-47, Receptor protein-tyrosine kinase HEK5, Renal carcinoma antigen NY-REN-47, TYRO5, Tyrosine-protein kinase TYRO5, Tyrosine-protein kinase receptor EPH-3
ID gène 2048, 9606
UniProt P29323
Pathways Signalisation RTK, Regulation of long-term Neuronal Synaptic Plasticity

Information d'application

Détail du produit anti-EPH Receptor B2 anticorps Détail du antigène EPH Receptor B2 Stockage References for anti-EPH Receptor B2 antibody (ABIN359812) Images Haut de la page
Indications d'application ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Stockage

Détail du produit anti-EPH Receptor B2 anticorps Détail du antigène EPH Receptor B2 Information d'application References for anti-EPH Receptor B2 antibody (ABIN359812) Images Haut de la page
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-EPH Receptor B2 antibody (ABIN359812)

Détail du produit anti-EPH Receptor B2 anticorps Détail du antigène EPH Receptor B2 Information d'application Stockage Images Haut de la page
Background publications

Thanos, Goodwill, Bowie: "Oligomeric structure of the human EphB2 receptor SAM domain." dans: Science (New York, N.Y.), Vol. 283, Issue 5403, pp. 833-6, 1999

Tang, Pleasure, Brodeur, Ikegaki: "A variant transcript encoding an isoform of the human protein tyrosine kinase EPHB2 is generated by alternative splicing and alternative use of polyadenylation signals." dans: Oncogene, Vol. 17, Issue 4, pp. 521-6, 1998

Ikegaki, Tang, Liu, Biegel, Allen, Yoshioka, Sulman, Brodeur, Pleasure: "Molecular characterization and chromosomal localization of DRT (EPHT3): a developmentally regulated human protein-tyrosine kinase gene of the EPH family." dans: Human molecular genetics, Vol. 4, Issue 11, pp. 2033-45, 1996

Fox, Holst, Chute, Lindberg, Janssen, Basu, Welcher: "cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases." dans: Oncogene, Vol. 10, Issue 5, pp. 897-905, 1995

Iwase, Tanaka, Suzuki, Naito, Sugimura, Kino: "Identification of protein-tyrosine kinase genes preferentially expressed in embryo stomach and gastric cancer." dans: Biochemical and biophysical research communications, Vol. 194, Issue 2, pp. 698-705, 1993

Images

Détail du produit anti-EPH Receptor B2 anticorps Détail du antigène EPH Receptor B2 Information d'application Stockage References for anti-EPH Receptor B2 antibody (ABIN359812) Haut de la page
Images (Fournisseur)
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-EPH Receptor B2 (EPHB2) (N-Term) antibody (ABIN359812) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Western Blotting (WB) image for anti-EPH Receptor B2 (EPHB2) (N-Term) antibody (ABIN359812) Western blot analysis of anti-EphB2 Pab in mouse heart tissue. EphB2 (Arrow) was dete...