Use your antibodies-online credentials, if available.
Il n’y a pas de produits dans votre liste de comparaison.
Votre panier est vide.
Afficher toutes les espèces
Afficher tous les synonymes
Select your species
It functioned by interrupting the phosphorylation of EphrinB2 and its related signaling pathway.
EphrinB2 affects apical constriction in Xenopus embryos and is regulated by ADAM10 (Montrer ADAM10 Kits ELISA) and flotillin-1 (Montrer FLOT1 Kits ELISA).
As endothelial progenitor cells (EPCs)derived from mouse bone marrow were cultured on substrates of increasing stiffness, the mRNA and protein levels of the specific arterial endothelial cell marker ephrinB2 were found to increase, while the expression of the venous marker EphB4 (Montrer EPHB4 Kits ELISA) decreased
an autonomous receptor-like role for ephrin-B reverse signaling in the tangential migration of interneurons into the neocortex using ephrin-B (EfnB1 (Montrer EFNB1 Kits ELISA)/B2/B3) conditional triple mutant (TM(lz)) mice, is reported.
During urogenital development, different modes of Eph (Montrer EPHA1 Kits ELISA)/Ephrin signaling occur at several sites with EphrinB2 and EphrinA5 acting in concert.
Male Efnb2 knockout mice presented reduced blood pressure. Region from aa 313 to aa 331 of EFNB2 was essential for reverse signaling regulating VSMC contractility.
Suggest role for ephrinB2/EphB4 (Montrer EPHB4 Kits ELISA) signaling in the maintenance of neurovascular homeostasis and show that EphrinB2 activation promotes vascular repair mechanisms and reduces brain swelling after mild cerebral ischemia.
The Eph (Montrer EPHA1 Kits ELISA)/ephrin-B2-mediated heterotypic or homotypic cell interactions between thymocytes and thymic epithelial cells (TECs), or between TECs and themselves, contribute to the early maturation of MTS20(+) TECs.
Control of abscission requires Eph (Montrer EPHA1 Kits ELISA) kinase activity, and Src (Montrer SRC Kits ELISA) and citron kinase (Montrer CIT Kits ELISA) (CitK) are downstream effectors in the Eph (Montrer EPHA1 Kits ELISA)-induced signal transduction cascade
The Netrin-1 (Montrer NTN1 Kits ELISA) and ephrin-B2 synergistic growth cone responses involve the potentiation of Src (Montrer SRC Kits ELISA) family kinase signaling, a common effector of both pathways.
in vivo study demonstrated, for the first time, that EFNB2 is essential for normal long bone growth and development
the role of ephrin B2 in endochondral ossification using Osx1Cre-targeted gene deletion, was investigated.
the binding of the viral attachment protein G to its host receptor ephrinB2 was studied and showed monomeric and dimeric receptors activate distinct conformational changes in G.
results suggest that ephrin-B2 overexpression and activation of the ephrin-B2 reverse signaling pathway in tumor microenvironment in OSCC facilitates progression and lymph node metastasis via enhancement of malignant potential and interaction with surrounding cells
Proteomic analysis of their secretome reveals a signature, including ephrin-B2, that predicts decreased survival of glioma patients. We find that ephrin-B2 is an important pro-angiogenic tenascin-C (Montrer TNC Kits ELISA) effector.
In human glioblastoma stem-like cells-derived orthotopic xenografts, EFNB2 knock-down blocked tumour initiation and treatment of established tumours with ephrin-B2-blocking antibodies suppressed progression.
High EFNB2 expression is associated with preeclampsia.
Inhibition of EphB4 (Montrer EPHB4 Kits ELISA) forward signaling using soluble EphB4 (Montrer EPHB4 Kits ELISA) protein fused (Montrer AXIN1 Kits ELISA) with murine serum albumin (Montrer ALB Kits ELISA) failed to affect eRMS model tumor progression, but did moderately slow progression in murine aRMS
Study shows that EFNB2 is overexpressed in head and neck squamous cell carcinoma, pancreatic adenocarcinoma, and urothelial bladder carcinoma, and its overexpression correlates with poor survival of the cancer patients.
Five SNPs in the 3' region of the EFNB2 were in linkage disequilibrium and significantly associated with hypertension for male but not female subjects.
These results indicate a novel mechanism of ephrin-Eph (Montrer EPHA1 Kits ELISA) signaling independent of direct cell contact and proteolytic cleavage and suggest the participation of EphB2 (Montrer EPHB2 Kits ELISA)(+)extracellular vesicles in neural development and synapse physiology.
Association of EFNB2 rs9520087 with symptoms of schizophrenia in Chinese Zhuang and Han populations.
The porcine EFNB2 gene was characterized and cloned. The porcine EFNB2 gene was expressed in ten different tissues from 25-day-old Shaziling and Yorkshire piglets, with the highest expression observed in the longissimus dorsi.
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors.
, ephrin-B2 precursor
, ephrin B2
, EPH-related receptor tyrosine kinase ligand 5
, HTK ligand
, eph-related receptor tyrosine kinase ligand 5
, ligand of eph-related kinase 5