anti-Humain KIT anticorps pour Intracellular Flow Cytometry

Recommended KIT Antibody

Antigène
Mast/stem Cell Growth Factor Receptor (KIT) Anticorps
  • C-Kit
  • CD117
  • PBT
  • SCFR
  • Bs
  • Fdc
  • Gsfsco1
  • Gsfsco5
  • Gsfsow3
  • SCO1
  • SCO5
  • SOW3
  • Ssm
  • Tr-kit
  • W
  • c-KIT
  • c-kit
  • MGF
  • KIT
  • C-KIT
  • kit
  • receptor
  • sparse
  • Xkl-1
  • kit-a
  • kit-b
  • kl1-A
  • krk1
  • pbt
  • scfr
  • KIT proto-oncogene receptor tyrosine kinase
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a
  • KIT proto-oncogene receptor tyrosine kinase S homeolog
  • KIT
  • Kit
  • kita
  • kit
  • kit.S
Reactivité
Humain
1366
478
172
45
45
38
26
19
14
5
4
4
4
3
2
1
1
1
Hôte
Souris
1096
364
161
14
2
2
Clonalité
Monoclonal
Conjugué
Cet anticorp KIT est conjugé à/à la PE
146
134
128
109
86
76
21
17
15
14
14
14
8
8
8
8
8
8
6
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
2
2
1
1
1
1
Application
Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
677
654
446
363
218
152
120
105
71
68
55
29
19
13
11
10
3
2
2
2
1
1
1
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Images

N° du produit ABIN2662956
Produit non disponible pour cette région.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
1 ABIN2662957 FACS ICFC PE Mouse IgG1 kappa A3C6E2 2

General

Antigène Mast/stem Cell Growth Factor Receptor (KIT) Anticorps
Reactivité Humain
(1366), (478), (172), (45), (45), (38), (26), (19), (14), (5), (4), (4), (4), (3), (2), (1), (1), (1)
Hôte Souris
(1096), (364), (161), (14), (2), (2)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp KIT est conjugé à/à la PE
(146), (134), (128), (109), (86), (76), (21), (17), (15), (14), (14), (14), (8), (8), (8), (8), (8), (8), (6), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
(677), (654), (446), (363), (218), (152), (120), (105), (71), (68), (55), (29), (19), (13), (11), (10), (3), (2), (2), (2), (1), (1), (1)
Pubmed 2 références disponible
Fournisseur

Détail du produit anti-KIT anticorps

Détail du antigène KIT Information d'application Stockage References for anti-KIT antibody (ABIN2662956) Images
Purification The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Clone A3C6E2
Isotype IgG1 kappa
Plasmids, Primers & others

Détail du antigène KIT

Détail du produit anti-KIT anticorps Information d'application Stockage References for anti-KIT antibody (ABIN2662956) Images Haut de la page
Antigène
Autre désignation CD117 (KIT Antibody Extrait)
Sujet CD117 is a 145 kD protein tyrosine kinase also known as c-Kit. It is a receptor for stem cell factor or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells (approximately 1-4 % bone marrow cells), mast cells, and acute myeloid leukemic cells (AML). CD117 binding of c-Kit ligand induces phosphorylation of CD117, and stimulates proliferation and survival of primitive hematopoietic stem cells as well as erythroid-committed and granulo-monocytic committed cells. The A3C6E2 antibody potently blocks the binding of SCF.
Pathways Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity

Information d'application

Détail du produit anti-KIT anticorps Détail du antigène KIT Stockage References for anti-KIT antibody (ABIN2662956) Images Haut de la page
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Stockage

Détail du produit anti-KIT anticorps Détail du antigène KIT Information d'application References for anti-KIT antibody (ABIN2662956) Images Haut de la page
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Protect from prolonged exposure to light. Do not freeze.
Stock 4 °C
Stockage commentaire The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-KIT antibody (ABIN2662956)

Détail du produit anti-KIT anticorps Détail du antigène KIT Information d'application Stockage Images Haut de la page
Background publications

Furitsu, Tsujimura, Tono, Ikeda, Kitayama, Koshimizu, Sugahara, Butterfield, Ashman, Kanayama: "Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product." dans: The Journal of clinical investigation, Vol. 92, Issue 4, pp. 1736-44, 1993

Giebel, Strunk, Holmes, Spritz: "Organization and nucleotide sequence of the human KIT (mast/stem cell growth factor receptor) proto-oncogene." dans: Oncogene, Vol. 7, Issue 11, pp. 2207-17, 1992

Images

Détail du produit anti-KIT anticorps Détail du antigène KIT Information d'application Stockage References for anti-KIT antibody (ABIN2662956) Haut de la page
Images (Fournisseur)
Flow Cytometry (FACS) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) antibody (PE) (ABIN2662956) anti-Mast/stem Cell Growth Factor Receptor (KIT) antibody (PE)