anti-Humain KIT anticorps pour Immunohistochemistry (Formalin-fixed Sections)

Recommended KIT Antibody

Antigène
Mast/stem Cell Growth Factor Receptor (KIT) Anticorps
  • C-Kit
  • CD117
  • PBT
  • SCFR
  • Bs
  • Fdc
  • Gsfsco1
  • Gsfsco5
  • Gsfsow3
  • SCO1
  • SCO5
  • SOW3
  • Ssm
  • Tr-kit
  • W
  • c-KIT
  • c-kit
  • MGF
  • KIT
  • C-KIT
  • kit
  • receptor
  • sparse
  • Xkl-1
  • kit-a
  • kit-b
  • kl1-A
  • krk1
  • pbt
  • scfr
  • KIT proto-oncogene receptor tyrosine kinase
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a
  • KIT proto-oncogene receptor tyrosine kinase S homeolog
  • KIT
  • Kit
  • kita
  • kit
  • kit.S
Reactivité
Humain, Non-Human Primate, Boeuf (Vache)
1365
478
172
45
45
37
26
19
14
4
4
4
4
3
2
1
1
1
Hôte
Souris
1096
363
161
14
2
2
Clonalité
Monoclonal
Conjugué
Cet anticorp KIT est conjugé à/à la PE
145
134
128
109
86
76
21
17
15
14
14
14
8
8
8
8
8
8
6
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
2
2
1
1
1
1
Application
Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunoprecipitation (IP)
677
654
445
363
218
152
120
105
70
67
55
28
19
13
11
10
3
2
2
2
1
1
1
Options

Images

N° du produit ABIN571351
$ 497.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
28.593636 ABIN1027690 IHC (f) ICC FACS IP APC Mouse IgG1 104D2 8
28.593636 ABIN1302740 FACS ICC IHC (f) IP Biotin Mouse IgG1 104D2 7
25.593636 ABIN638436 FACS ICC IHC (f) IP FITC Mouse IgG1 104D2 8
25.593636 ABIN571350 FACS ICC IHC (f) IP Mouse IgG1 104D2 7
4 ABIN6190672 FACS IF IHC (f) PE Mouse IgG1, kappa C117-370 0
4 ABIN6190664 FACS IF IHC (f) APC Mouse IgG1, kappa C117-370 0
4 ABIN6190671 FACS IF IHC (f) PerCP Mouse IgG1, kappa C117-370 0
4 ABIN6190702 FACS IF IHC (f) APC Mouse IgG Cocktail 0
4 ABIN6190709 FACS IF IHC (f) PerCP Mouse IgG Cocktail 0
4 ABIN6190710 FACS IF IHC (f) PE Mouse IgG Cocktail 0
4 ABIN6190785 FACS IF IHC (f) PerCP Mouse IgG1, kappa AA 100-300 KIT-983 0
4 ABIN6190786 FACS IF IHC (f) PE Mouse IgG1, kappa AA 100-300 KIT-983 0
4 ABIN6190778 FACS IF IHC (f) APC Mouse IgG1, kappa AA 100-300 KIT-983 0
4 ABIN6190675 FACS IF IHC (f) Mouse IgG1, kappa C117-370 0
4 ABIN6190713 FACS IF IHC (f) Mouse IgG Cocktail 0
4 ABIN6190789 FACS IF IHC (f) Mouse IgG1, kappa AA 100-300 KIT-983 0
1 ABIN6190640 FACS IF IHC (f) CF405M Mouse IgG1, kappa C117-370 0
1 ABIN6190638 FACS IF IHC (f) CF®405S Mouse IgG1, kappa C117-370 0
1 ABIN6190660 FACS IF IHC (f) CF®488A Mouse IgG1, kappa C117-370 0
1 ABIN6190644 FACS IF IHC (f) CF®543 Mouse IgG1, kappa C117-370 0

General

Antigène Mast/stem Cell Growth Factor Receptor (KIT) Anticorps
Reactivité Humain, Non-Human Primate, Boeuf (Vache)
(1365), (478), (172), (45), (45), (37), (26), (19), (14), (4), (4), (4), (4), (3), (2), (1), (1), (1)
Hôte Souris
(1096), (363), (161), (14), (2), (2)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp KIT est conjugé à/à la PE
(145), (134), (128), (109), (86), (76), (21), (17), (15), (14), (14), (14), (8), (8), (8), (8), (8), (8), (6), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunoprecipitation (IP)
(677), (654), (445), (363), (218), (152), (120), (105), (70), (67), (55), (28), (19), (13), (11), (10), (3), (2), (2), (2), (1), (1), (1)
Pubmed 8 références disponible
Fournisseur

Détail du produit anti-KIT anticorps

Détail du antigène KIT Information d'application Stockage References for anti-KIT antibody (ABIN571351) Images
Specificité The mouse monoclonal antibody 104D2 detects extracellular part of CD117 / c-Kit protooncogen.
HLDA VI, WS Code C-30
Réactivité croisée (Details) Human, Non-Human Primates, Bovine
Immunogène MOLM-1 megakaryocytic cells
Clone 104D2
Isotype IgG1
Plasmids, Primers & others

Détail du antigène KIT

Détail du produit anti-KIT anticorps Information d'application Stockage References for anti-KIT antibody (ABIN571351) Images Haut de la page
Antigène
Autre désignation CD117 (KIT Antibody Extrait)
Sujet CD117 / c-Kit (stem cell factor receptor) is a 145 kDa receptor tyrosine kinase that regulates cell proliferation, adhesion, chemotaxis, apoptosis and other cell processes. Mutations of CD117 / c-Kit can lead to growth and progression of tumours. After binding of its ligand, SCF (stem cell factor), CD117 / c-Kit is autophosphorylated on its intracellular domains and activated. CD117 is expressed on pluripotent hematopoietic progenitor cells, mast cells and various cancer cells, e.g. acute myeloid leukemia cells.
ID gène 3815
Pathways Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity

Information d'application

Détail du produit anti-KIT anticorps Détail du antigène KIT Stockage References for anti-KIT antibody (ABIN571351) Images Haut de la page
Indications d'application The reagent is designed for Flow Cytometry analysis of human blood cells using 20 μ,l reagent / 100 μ,l of whole blood or 106 cells in a suspension.The content of a vial (2 ml) is sufficient for 100 tests.
Commentaires

The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

Restrictions For Research Use only

Stockage

Détail du produit anti-KIT anticorps Détail du antigène KIT Information d'application References for anti-KIT antibody (ABIN571351) Images Haut de la page
Reconstitution No reconstitution is necessary.
Buffer The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do not freeze.
Avoid prolonged exposure to light.
Stock 4 °C
Stockage commentaire Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.

References for anti-KIT antibody (ABIN571351)

Détail du produit anti-KIT anticorps Détail du antigène KIT Information d'application Stockage Images Haut de la page
Produit citée dans:

Stevenson, McGlynn, Hodge, McLinden, George, Davies, Shiels: "Isolation, characterization, and differentiation of thy1.1-sorted pancreatic adult progenitor cell populations." dans: Stem cells and development, Vol. 18, Issue 10, pp. 1389-98, 2009

Nagano, Yamashita, Hamada, Ohneda, Kimura, Nakagawa, Shibuya, Yoshikawa, Ohneda: "Identification of functional endothelial progenitor cells suitable for the treatment of ischemic tissue using human umbilical cord blood." dans: Blood, Vol. 110, Issue 1, pp. 151-60, 2007

Wihlidal, Varga, Pfeilstöcker, Karlic: "Expression and functional significance of osteocalcin splicing in disease progression of hematological malignancies." dans: Leukemia research, Vol. 30, Issue 10, pp. 1241-8, 2006

Blair, Sutherland: "Primitive acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo lack surface expression of c-kit (CD117)." dans: Experimental hematology, Vol. 28, Issue 6, pp. 660-71, 2000

Yoshino, Ami, Terao, Tashiro, Honda: "Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies." dans: Experimental animals / Japanese Association for Laboratory Animal Science, Vol. 49, Issue 2, pp. 97-110, 2000

Broudy, Lin, Liles, Corey, OLaughlin, Mou, Linnekin: "Signaling via Src family kinases is required for normal internalization of the receptor c-Kit." dans: Blood, Vol. 94, Issue 6, pp. 1979-86, 1999

Broudy, Lin, Bühring, Komatsu, Kavanagh: "Analysis of c-kit receptor dimerization by fluorescence resonance energy transfer." dans: Blood, Vol. 91, Issue 3, pp. 898-906, 1998

Rappold, Ziegler, Köhler, Marchetto, Rosnet, Birnbaum, Simmons, Zannettino, Hill, Neu, Knapp, Alitalo, Alitalo, Ullrich, Kanz, Bühring: "Functional and phenotypic characterization of cord blood and bone marrow subsets expressing FLT3 (CD135) receptor tyrosine kinase." dans: Blood, Vol. 90, Issue 1, pp. 111-25, 1997

Images

Détail du produit anti-KIT anticorps Détail du antigène KIT Information d'application Stockage References for anti-KIT antibody (ABIN571351) Haut de la page
Images (Fournisseur)
Flow Cytometry (FACS) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) antibody (PE) (ABIN571351) Surface staining of human peripheral blood cells with anti-CD117 (104D2) purified.
Flow Cytometry (FACS) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) antibody (PE) (ABIN571351) Surface staining of human peripheral blood cells with anti-CD117 (104D2) PE.