anti-Humain KIT anticorps pour Immunohistochemistry (Paraffin-embedded Sections)

Recommended KIT Antibody

Antigène
Mast/stem Cell Growth Factor Receptor (KIT) Anticorps
  • C-Kit
  • CD117
  • PBT
  • SCFR
  • Bs
  • Fdc
  • Gsfsco1
  • Gsfsco5
  • Gsfsow3
  • SCO1
  • SCO5
  • SOW3
  • Ssm
  • Tr-kit
  • W
  • c-KIT
  • c-kit
  • MGF
  • KIT
  • C-KIT
  • kit
  • receptor
  • sparse
  • Xkl-1
  • kit-a
  • kit-b
  • kl1-A
  • krk1
  • pbt
  • scfr
  • KIT proto-oncogene receptor tyrosine kinase
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a
  • KIT proto-oncogene receptor tyrosine kinase S homeolog
  • KIT
  • Kit
  • kita
  • kit
  • kit.S
Épitope
AA 26-285
69
67
65
65
51
47
34
33
32
32
26
25
23
20
18
18
18
18
18
18
17
17
17
17
17
17
17
17
17
17
17
15
15
15
15
15
12
11
10
10
10
9
9
9
9
9
9
9
9
8
8
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
6
5
5
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain
1323
467
170
45
44
38
26
19
14
5
4
4
4
3
2
1
1
1
Hôte
Lapin
1052
360
161
14
2
2
Clonalité
Polyclonal
Conjugué
Cet anticorp KIT est non-conjugé
146
134
128
109
86
76
21
17
15
14
14
14
8
8
8
8
8
8
6
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
2
2
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
674
625
441
347
212
151
116
105
70
68
55
29
18
13
11
10
3
2
2
2
1
1
1
Options

Images

N° du produit ABIN3042739
$ 280.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
24.90403 ABIN1387260 IF (cc) IF (p) IHC (p) WB Rabbit IgG AA 360-405 Polyclonal 3
20.5 ABIN561600 IHC (p) ELISA WB Mouse IgG AA 41-140 4F7 1
19 ABIN1491585 IHC IHC (p) WB Mouse IgG2a AA 546-976 2E3 0
19 ABIN3031690 FACS IHC (p) WB Rabbit IgG AA 26-285 Polyclonal 0
18.90403 ABIN1999477 IHC (p) ELISA Rabbit IgG AA 1-516 351 1
18.90403 ABIN743393 IF (p) IHC (p) WB Rabbit IgG AA 700-750, pTyr721 Polyclonal 1
16.701527 ABIN1019976 IHC (p) Rabbit IgG C-Term Polyclonal 0
16.701527 ABIN1019975 IHC (p) Rabbit IgG C-Term Polyclonal 0
16.701527 ABIN870476 IHC (fro) IHC (p) Rabbit C-Term R21-V 0
16.701527 ABIN870479 IHC (fro) IHC (p) Rabbit C-Term R21-V 0
16 ABIN948058 IHC (p) ELISA WB Mouse IgG2b kappa AA 41-140 X1 0
16 ABIN5649362 IHC (p) WB Mouse IgG2a CL1667 0
16 ABIN5649361 IHC (p) WB Mouse IgG1 CL1657 0
15.90403 ABIN671721 IF (p) IHC (p) WB Rabbit IgG AA 928-964 Polyclonal 3
14.5 ABIN544317 IHC (p) ELISA WB Rabbit Polyclonal 3
13.701527 ABIN4901112 ELISA IHC (p) WB Mouse IgG1 8D7 0
13.701527 ABIN4901113 ELISA IHC (p) WB Mouse IgG1 1C5 0
13.701527 ABIN637007 IHC (p) Rabbit Polyclonal 0
13 ABIN561594 IHC (p) PLA ELISA WB Mouse IgG2b kappa AA 41-140 6G12 0
13 ABIN561598 IHC (p) ELISA WB Mouse IgG2b kappa AA 41-140 5F6 0

General

Antigène Mast/stem Cell Growth Factor Receptor (KIT) Anticorps
Épitope AA 26-285
(69), (67), (65), (65), (51), (47), (34), (33), (32), (32), (26), (25), (23), (20), (18), (18), (18), (18), (18), (18), (17), (17), (17), (17), (17), (17), (17), (17), (17), (17), (17), (15), (15), (15), (15), (15), (12), (11), (10), (10), (10), (9), (9), (9), (9), (9), (9), (9), (9), (8), (8), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (6), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain
(1323), (467), (170), (45), (44), (38), (26), (19), (14), (5), (4), (4), (4), (3), (2), (1), (1), (1)
Hôte Lapin
(1052), (360), (161), (14), (2), (2)
Clonalité
Polyclonal
Conjugué Cet anticorp KIT est non-conjugé
(146), (134), (128), (109), (86), (76), (21), (17), (15), (14), (14), (14), (8), (8), (8), (8), (8), (8), (6), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(674), (625), (441), (347), (212), (151), (116), (105), (70), (68), (55), (29), (18), (13), (11), (10), (3), (2), (2), (2), (1), (1), (1)
Pubmed 15 références disponible
Fournisseur

Détail du produit anti-KIT anticorps

Détail du antigène KIT Information d'application Stockage References for anti-KIT antibody (ABIN3042739) Images
Fonction Rabbit IgG polyclonal antibody for Mast/stem cell growth factor receptor Kit(KIT) detection. Tested with WB, IHC-P, FCM in Human.
Réactivité croisée (Details) No cross reactivity with other proteins.
Attributs du produit Rabbit IgG polyclonal antibody for Mast/stem cell growth factor receptor Kit(KIT) detection. Tested with WB, IHC-P, FCM in Human.
Gene Name: v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Protein Name: Mast/stem cell growth factor receptor Kit
Purification Immunogen affinity purified.
Immunogène E.coli-derived human c-Kit recombinant protein (Position: Q26-S285). Human c-Kit shares 66% amino acid (aa) sequence identity with mouse c-Kit.
Isotype IgG
Plasmids, Primers & others

Détail du antigène KIT

Détail du produit anti-KIT anticorps Information d'application Stockage References for anti-KIT antibody (ABIN3042739) Images Haut de la page
Antigène
Autre désignation KIT (KIT Antibody Extrait)
Sujet SCFR(Mast/stem cell growth factor receptor), also known as KIT ONCOGENE or CD117, is a protein that in humans is encoded by the KIT gene. KIT was first described as the cellular homolog of the feline sarcoma viral oncogene v-kit. The KIT gene is mapped on 4q12. Kit was expressed on the surface of germ cells up to the pachytene stage. Signaling from the KIT receptor tyrosine kinase is essential for primordial germ cell growth both in vivo and in vitro. Determination of the KIT effectors acting in primordial germ cells has been hampered by the lack of effective methods to manipulate easily gene expression in these cells.

Synonyms: C Kit antibody|c-Kit antibody|CD 117 antibody|CD117 antibody|CD117 antigen antibody|KIT antibody|KIT oncogene antibody|KIT_HUMAN antibody|Mast cell growth factor receptor antibody|Mast/stem cell growth factor receptor antibody|Mast/stem cell growth factor receptor Kit antibody|p145 c-kit antibody|PBT antibody|Piebald trait protein antibody|Proto oncogene c Kit antibody|Proto oncogene tyrosine protein kinase Kit antibody|Proto-oncogene c-Kit antibody|SCF Receptor antibody|SCFR antibody|soluble KIT variant 1 antibody|Steel Factor Receptor antibody|Stem cell factor receptor antibody|tyrosine protein kinase Kit antibody|Tyrosine-protein kinase Kit antibody|v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog antibody|v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein antibody|v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog antibody
ID gène 3815
UniProt P10721
Pathways Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity

Information d'application

Détail du produit anti-KIT anticorps Détail du antigène KIT Stockage References for anti-KIT antibody (ABIN3042739) Images Haut de la page
Indications d'application WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for c-Kit is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Flow Cytometry: Concentration:1-3 μg/1x106 cells, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Commentaires

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions For Research Use only

Stockage

Détail du produit anti-KIT anticorps Détail du antigène KIT Information d'application References for anti-KIT antibody (ABIN3042739) Images Haut de la page
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-KIT antibody (ABIN3042739)

Détail du produit anti-KIT anticorps Détail du antigène KIT Information d'application Stockage Images Haut de la page
Produit citée dans:

Yang, Zhou, Lan: "Impact of the alterations in the interstitial cells of Cajal on intestinal motility in post-infection irritable bowel syndrome." dans: Molecular medicine reports, Vol. 11, Issue 4, pp. 2735-40, 2015

Li, Wang, Zhao, Yang, Li, Zhao, Yu, Wang, Meng, Liu, Zhu, Gao, Jia, Yang: "Nuclear factor of activated T cells 5 maintained by Hotair suppression of miR-568 upregulates S100 calcium binding protein A4 to promote breast cancer metastasis." dans: Breast cancer research : BCR, Vol. 16, Issue 5, pp. 454, 2015

Xu, Ge, Han, Yang, Su, Zhao, Zhao, Yang, Yang: "High-mobility group box 1 expression and lymph node metastasis in intrahepatic cholangiocarcinoma." dans: World journal of gastroenterology : WJG, Vol. 21, Issue 11, pp. 3256-65, 2015

Jiang, Li, Zhou, Wang, Zhang, Wang: "Colistin-induced apoptosis in PC12 cells: involvement of the mitochondrial apoptotic and death receptor pathways." dans: International journal of molecular medicine, Vol. 33, Issue 5, pp. 1298-304, 2014

Ban, Fan, Huang, Li, Chen, Zhang, Xu: "Mono-(2-ethylhexyl) phthalate induces injury in human umbilical vein endothelial cells." dans: PLoS ONE, Vol. 9, Issue 5, pp. e97607, 2014

Tang, Li, Yu, Gao, Liu, Chen, Xing, Liu, Yao: "Quercetin prevents ethanol-induced iron overload by regulating hepcidin through the BMP6/SMAD4 signaling pathway." dans: The Journal of nutritional biochemistry, Vol. 25, Issue 6, pp. 675-82, 2014

Cheng, Wu, Gao, Xu: "Analysis of influence of baicalin joint resveratrol retention enema on the TNF-?, SIgA, IL-2, IFN-? of rats with respiratory syncytial virus infection." dans: Cell biochemistry and biophysics, Vol. 70, Issue 2, pp. 1305-9, 2014

Liu, Peng, Lin, Luo, Jiang, Mo, Yung: "Effect of rhynchophylline on the expression of p-CREB and sc-Fos in triatum and hippocampal CA1 area of methamphetamine-induced conditioned place preference rats." dans: Fitoterapia, Vol. 92, pp. 16-22, 2014

Zhang, Li, Xu, Mei, Zhang, Murong, Sun, Tong: "Changes of c-fos, malondialdehyde and lactate in brain tissue after global cerebral ischemia under different brain temperatures." dans: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 34, Issue 3, pp. 354-8, 2014

Liu, Wang, Du, Liu, Liu, Zhang, Zhang, Hou, Liu, Zhang, Yu: "Wnt1 inhibits hydrogen peroxide-induced apoptosis in mouse cardiac stem cells." dans: PLoS ONE, Vol. 8, Issue 3, pp. e58883, 2013

Chuangui, Peng, Zhentao: "The expression of high mobility group box 1 is associated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma." dans: Pathology oncology research : POR, Vol. 18, Issue 4, pp. 1021-7, 2012

Bin, Ma, Xu, Shi: "Embryonic hepatocyte transplantation for hepatic cirrhosis: efficacy and mechanism of action." dans: World journal of gastroenterology, Vol. 18, Issue 4, pp. 309-22, 2012

Lan, Yue, Han, Shi, Yang, Pu, Yao, Kang: "Genome-wide identification of TCF7L2/TCF4 target miRNAs reveals a role for miR-21 in Wnt-driven epithelial cancer." dans: International journal of oncology, Vol. 40, Issue 2, pp. 519-26, 2011

Bao, Liu, Qin, Xu, Hei, Jaber, Chen: "An immunohistochemical study of S-100 protein in the intestinal tract of Chinese soft-shelled turtle, Pelodiscus sinensis." dans: Research in veterinary science, Vol. 91, Issue 3, pp. e16-24, 2011

Ge, Zhang, Ye, Tang, Wu: "Ginsenosides promote proliferation of chicken primordial germ cells via PKC-involved activation of NF-kappaB." dans: Cell biology international, Vol. 31, Issue 10, pp. 1251-6, 2007

Images

Détail du produit anti-KIT anticorps Détail du antigène KIT Information d'application Stockage References for anti-KIT antibody (ABIN3042739) Haut de la page
Images (Fournisseur)
Western Blotting (WB) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 26-285) antibody (ABIN3042739) Anti- C-Kit Picoband antibody, Western blotting All lanes: Anti C-Kit at 0.5ug/ml WB...
Immunohistochemistry (IHC) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 26-285) antibody (ABIN3042739) Anti- C-Kit Picoband antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue
Western Blotting (WB) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 26-285) antibody (ABIN3042739) Anti- C-Kit Picoband antibody, Western blotting All lanes: Anti C-Kit at 0.5ug/ml WB...
Flow Cytometry (FACS) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 26-285) antibody (ABIN3042739) Flow Cytometry analysis of K562 cells using anti-C-Kit antibody . Overlay histogram s...