anti-Singe KIT anticorps pour Immunohistochemistry (Paraffin-embedded Sections)

Recommended KIT Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Mast/stem Cell Growth Factor Receptor (KIT) Anticorps
  • C-Kit
  • CD117
  • PBT
  • SCFR
  • Bs
  • Fdc
  • Gsfsco1
  • Gsfsco5
  • Gsfsow3
  • SCO1
  • SCO5
  • SOW3
  • Ssm
  • Tr-kit
  • W
  • c-KIT
  • c-kit
  • MGF
  • KIT
  • C-KIT
  • kit
  • receptor
  • sparse
  • Xkl-1
  • kit-a
  • kit-b
  • kl1-A
  • krk1
  • pbt
  • scfr
  • KIT proto-oncogene receptor tyrosine kinase
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a
  • KIT proto-oncogene receptor tyrosine kinase S homeolog
  • KIT
  • Kit
  • kita
  • kit
  • kit.S
Épitope
AA 9-40, N-Term
74
74
68
62
51
49
35
33
33
32
26
25
20
19
19
19
19
19
18
18
18
18
18
18
18
18
18
17
17
17
16
15
15
15
15
13
12
11
11
11
10
10
10
10
10
10
10
10
9
9
9
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
5
5
5
5
5
4
4
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Singe
1429
595
173
45
44
38
26
22
14
5
4
4
4
4
3
1
1
1
Hôte
Lapin
1061
439
275
18
2
2
Clonalité
Polyclonal
Conjugué
Cet anticorp KIT est non-conjugé
156
142
135
118
90
76
22
18
15
13
10
10
10
10
9
8
8
8
8
8
8
7
7
6
5
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
3
2
2
2
2
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
704
699
576
363
312
175
165
124
105
84
68
39
19
13
12
10
8
6
5
4
3
3
3
3
3
2
2
2
2
1
1
Options
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N° du produit ABIN392008
$ 385.00
Plus shipping costs $45.00

General

Antigène Mast/stem Cell Growth Factor Receptor (KIT) Anticorps
Épitope AA 9-40, N-Term
(74), (74), (68), (62), (51), (49), (35), (33), (33), (32), (26), (25), (20), (19), (19), (19), (19), (19), (18), (18), (18), (18), (18), (18), (18), (18), (18), (17), (17), (17), (16), (15), (15), (15), (15), (13), (12), (11), (11), (11), (10), (10), (10), (10), (10), (10), (10), (10), (9), (9), (9), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (5), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain, Singe
(1429), (595), (173), (45), (44), (38), (26), (22), (14), (5), (4), (4), (4), (4), (3), (1), (1), (1)
Hôte Lapin
(1061), (439), (275), (18), (2), (2)
Clonalité (Clone)
Polyclonal   ( )
Conjugué Cet anticorp KIT est non-conjugé
(156), (142), (135), (118), (90), (76), (22), (18), (15), (13), (10), (10), (10), (10), (9), (8), (8), (8), (8), (8), (8), (7), (7), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2)
Application Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(704), (699), (576), (363), (312), (175), (165), (124), (105), (84), (68), (39), (19), (13), (12), (10), (8), (6), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1)
Pubmed 4 références disponible
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Détail du produit anti-KIT anticorps

Détail du antigène KIT Information d'application Stockage References for anti-KIT antibody (ABIN392008) Images
Specificité This c-KIT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human KIT.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogène This c-KIT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-40 AA from the N-terminal region of human c-KIT.
Clone RB1558
Isotype Ig Fraction
Plasmids, Primers & others

Détail du antigène KIT

Détail du produit anti-KIT anticorps Information d'application Stockage References for anti-KIT antibody (ABIN392008) Images Haut de la page
Antigène
Autre désignation c-KIT (KIT Antibody Extrait)
Sujet KIT encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.
Synonyms: Mast/stem cell growth factor receptor, Proto-oncogene tyrosine-protein kinase Kit, SCFR, CD117 antigen
Poids moléculaire 109864 Da
ID gène 3815
UniProt Q99662
Pathways Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity

Information d'application

Détail du produit anti-KIT anticorps Détail du antigène KIT Stockage References for anti-KIT antibody (ABIN392008) Images Haut de la page
Indications d'application WB = 1:1000, IHC (p) = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only

Stockage

Détail du produit anti-KIT anticorps Détail du antigène KIT Information d'application References for anti-KIT antibody (ABIN392008) Images Haut de la page
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C/-20 °C
Stockage commentaire Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Date de péremption 6 months

References for anti-KIT antibody (ABIN392008)

Détail du produit anti-KIT anticorps Détail du antigène KIT Information d'application Stockage Images Haut de la page
Produit citée dans:

Wright, Robles, Herschkowitz, Hollingshead, Anver, Perou, Varticovski: "Molecular analysis reveals heterogeneity of mouse mammary tumors conditionally mutant for Brca1." dans: Molecular cancer, Vol. 7, pp. 29, 2008 Méthode utilisée: Flow Cytometry (FACS)

Background publications

Wardelmann, Losen, Hans, Neidt, Speidel, Bierhoff, Heinicke, Pietsch, Büttner, Merkelbach-Bruse: "Deletion of Trp-557 and Lys-558 in the juxtamembrane domain of the c-kit protooncogene is associated with metastatic behavior of gastrointestinal stromal tumors." dans: International journal of cancer. Journal international du cancer, Vol. 106, Issue 6, pp. 887-95, 2003

Voytyuk, Lennartsson, Mogi, Caruana, Courtneidge, Ashman, Rönnstrand: "Src family kinases are involved in the differential signaling from two splice forms of c-Kit." dans: The Journal of biological chemistry, Vol. 278, Issue 11, pp. 9159-66, 2003

Araki, Ishii, Yokose, Nagai, Funai, Kodama, Nishiwaki, Ochiai: "Frequent overexpression of the c-kit protein in large cell neuroendocrine carcinoma of the lung." dans: Lung cancer (Amsterdam, Netherlands), Vol. 40, Issue 2, pp. 173-80, 2003

Images

Détail du produit anti-KIT anticorps Détail du antigène KIT Information d'application Stockage References for anti-KIT antibody (ABIN392008) Haut de la page
Images (Fournisseur)
Western Blotting (WB) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 9-40), (N-Term) antibody (ABIN392008) The anti-KIT Pab (ABIN392008) is used in Western blot to detect KIT in serum-starved ...
Immunohistochemistry (IHC) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 9-40), (N-Term) antibody (ABIN392008) Purified rabbit anti-hKIT-S24 Pab was used in immunohistochemistry on Breast Carcinoma.
Flow Cytometry (FACS) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 9-40), (N-Term) antibody (ABIN392008) Flow cytometric analysis of hela cells using c-KIT Antibody (N-term)(bottom histogram...