anti-Souris KIT anticorps pour Intracellular Flow Cytometry

Recommended KIT Antibody

Antigène
Mast/stem Cell Growth Factor Receptor (KIT) Anticorps
  • C-Kit
  • CD117
  • PBT
  • SCFR
  • Bs
  • Fdc
  • Gsfsco1
  • Gsfsco5
  • Gsfsow3
  • SCO1
  • SCO5
  • SOW3
  • Ssm
  • Tr-kit
  • W
  • c-KIT
  • c-kit
  • MGF
  • KIT
  • C-KIT
  • kit
  • receptor
  • sparse
  • Xkl-1
  • kit-a
  • kit-b
  • kl1-A
  • krk1
  • pbt
  • scfr
  • KIT proto-oncogene receptor tyrosine kinase
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a
  • KIT proto-oncogene receptor tyrosine kinase S homeolog
  • KIT
  • Kit
  • kita
  • kit
  • kit.S
Reactivité
Souris
1366
478
172
45
45
38
26
19
14
5
4
4
4
3
2
1
1
1
Hôte
Rat
1096
364
161
14
2
2
Clonalité
Monoclonal
Conjugué
Cet anticorp KIT est conjugé à/à la FITC
146
134
128
109
86
76
21
17
15
14
14
14
8
8
8
8
8
8
6
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
2
2
1
1
1
1
Application
ELISA (Detection), ELISpot (Detection) (ELISPOT (Detection)), Intracellular Flow Cytometry (ICFC)
677
654
446
363
218
152
120
105
71
68
55
29
19
13
11
10
3
2
2
2
1
1
1
Options

Images

N° du produit ABIN2661475
Produit non disponible pour cette région.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
7 ABIN2659827 ICFC PerCP Rat IgG2b kappa 2B8 7
7 ABIN2658450 ICFC APC Rat IgG2b kappa ACK2 6
1 ABIN2661474 ELISA (Detection) ELISPOT (Detection) ICFC FITC Rat IgG2b kappa 2B8 8
1 ABIN2659828 ICFC PerCP Rat IgG2b kappa 2B8 7
1 ABIN2658451 ICFC APC Rat IgG2b kappa ACK2 6

General

Antigène Mast/stem Cell Growth Factor Receptor (KIT) Anticorps
Reactivité Souris
(1366), (478), (172), (45), (45), (38), (26), (19), (14), (5), (4), (4), (4), (3), (2), (1), (1), (1)
Hôte Rat
(1096), (364), (161), (14), (2), (2)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp KIT est conjugé à/à la FITC
(146), (134), (128), (109), (86), (76), (21), (17), (15), (14), (14), (14), (8), (8), (8), (8), (8), (8), (6), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1)
Application ELISA (Detection), ELISpot (Detection) (ELISPOT (Detection)), Intracellular Flow Cytometry (ICFC)
(677), (654), (446), (363), (218), (152), (120), (105), (71), (68), (55), (29), (19), (13), (11), (10), (3), (2), (2), (2), (1), (1), (1)
Pubmed 8 références disponible
Fournisseur

Détail du produit anti-KIT anticorps

Détail du antigène KIT Information d'application Stockage References for anti-KIT antibody (ABIN2661475) Images
Purification The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Clone 2B8
Isotype IgG2b kappa
Plasmids, Primers & others

Détail du antigène KIT

Détail du produit anti-KIT anticorps Information d'application Stockage References for anti-KIT antibody (ABIN2661475) Images Haut de la page
Antigène
Autre désignation CD117 (KIT Antibody Extrait)
Sujet CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.
Pathways Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity

Information d'application

Détail du produit anti-KIT anticorps Détail du antigène KIT Stockage References for anti-KIT antibody (ABIN2661475) Images Haut de la page
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Stockage

Détail du produit anti-KIT anticorps Détail du antigène KIT Information d'application References for anti-KIT antibody (ABIN2661475) Images Haut de la page
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Protect from prolonged exposure to light. Do not freeze.
Stock 4 °C
Stockage commentaire The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-KIT antibody (ABIN2661475)

Détail du produit anti-KIT anticorps Détail du antigène KIT Information d'application Stockage Images Haut de la page
Background publications

Gough, Marié, Lobry, Aifantis, Levy: "STAT3 supports experimental K-RasG12D-induced murine myeloproliferative neoplasms dependent on serine phosphorylation." dans: Blood, Vol. 124, Issue 14, pp. 2252-61, 2014

Charles, Hardwick, Daugas, Illei, Rivera: "Basophils and the T helper 2 environment can promote the development of lupus nephritis." dans: Nature medicine, Vol. 16, Issue 6, pp. 701-7, 2010

Bachelet, Munitz, Berent-Maoz, Mankuta, Levi-Schaffer: "Suppression of normal and malignant kit signaling by a bispecific antibody linking kit with CD300a." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 9, pp. 6064-9, 2008

Podd, Thoits, Whitley, Cheng, Kudla, Taniguchi, Halkias, Goth, Camerini: "T cells in cryptopatch aggregates share TCR gamma variable region junctional sequences with gamma delta T cells in the small intestinal epithelium of mice." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 11, pp. 6532-42, 2006

Galli, Zsebo, Geissler: "The kit ligand, stem cell factor." dans: Advances in immunology, Vol. 55, pp. 1-96, 1994

Ikuta, Uchida, Friedman, Weissman: "Lymphocyte development from stem cells." dans: Annual review of immunology, Vol. 10, pp. 759-83, 1992

Ikuta, Weissman: "Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 4, pp. 1502-6, 1992

Witte: "Steel locus defines new multipotent growth factor." dans: Cell, Vol. 63, Issue 1, pp. 5-6, 1990

Images

Détail du produit anti-KIT anticorps Détail du antigène KIT Information d'application Stockage References for anti-KIT antibody (ABIN2661475) Haut de la page
Images (Fournisseur)
Flow Cytometry (FACS) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) antibody (FITC) (ABIN2661475) anti-Mast/stem Cell Growth Factor Receptor (KIT) antibody (FITC)
Flow Cytometry (FACS) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) antibody (FITC) (ABIN2661475) anti-Mast/stem Cell Growth Factor Receptor (KIT) antibody (FITC) (Image 2)