anti-Souris KIT anticorps pour Immunohistochemistry (Paraffin-embedded Sections)

Recommended KIT Antibody

Antigène
Mast/stem Cell Growth Factor Receptor (KIT) Anticorps
  • C-Kit
  • CD117
  • PBT
  • SCFR
  • Bs
  • Fdc
  • Gsfsco1
  • Gsfsco5
  • Gsfsow3
  • SCO1
  • SCO5
  • SOW3
  • Ssm
  • Tr-kit
  • W
  • c-KIT
  • c-kit
  • MGF
  • KIT
  • C-KIT
  • kit
  • receptor
  • sparse
  • Xkl-1
  • kit-a
  • kit-b
  • kl1-A
  • krk1
  • pbt
  • scfr
  • KIT proto-oncogene receptor tyrosine kinase
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a
  • KIT proto-oncogene receptor tyrosine kinase S homeolog
  • KIT
  • Kit
  • kita
  • kit
  • kit.S
Épitope
AA 360-405
74
71
69
68
51
48
35
33
33
32
27
26
26
20
19
19
19
19
19
18
18
18
18
18
18
18
18
18
17
17
17
16
15
15
15
14
12
12
11
11
10
10
10
10
10
10
10
10
9
9
9
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
5
5
5
4
4
4
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
1365
477
171
45
45
38
26
19
14
5
4
4
4
3
2
1
1
1
Hôte
Lapin
1095
364
161
14
2
2
Clonalité
Polyclonal
Conjugué
Cet anticorp KIT est non-conjugé
146
134
128
109
86
76
21
17
15
14
14
14
8
8
8
8
8
8
6
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
2
2
1
1
1
1
Application
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
677
653
446
363
218
152
119
104
71
68
55
29
19
12
11
10
3
2
2
2
1
1
1
Options

Images

N° du produit ABIN1387260
$ 329.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
19.085852 ABIN743393 IF (p) IHC (p) WB Rabbit IgG AA 700-750, pTyr721 Polyclonal 1
16.085852 ABIN671721 IF (p) IHC (p) WB Rabbit IgG AA 928-964 Polyclonal 3
13 ABIN392010 FACS IHC (p) WB Rabbit Ig Fraction AA 106-135, N-Term Polyclonal 3
10 ABIN5535795 FACS IHC (p) WB Rabbit Ig Fraction AA 106-135, N-Term Polyclonal 0
4 ABIN5962639 ELISA IHC (p) WB Rabbit IgG Tyr936 Polyclonal 0
4 ABIN498395 IHC (p) WB Rabbit Polyclonal 0
1 ABIN743402 IHC (p) WB HRP Rabbit IgG AA 700-750, pTyr721 Polyclonal 0
1 ABIN1406108 IHC (p) WB HRP Rabbit IgG AA 360-405 Polyclonal 0
1 ABIN743395 IHC (p) WB Biotin Rabbit IgG AA 700-750, pTyr721 Polyclonal 0
1 ABIN671730 IHC (p) WB HRP Rabbit IgG AA 928-964 Polyclonal 0
1 ABIN1712419 IHC (p) WB HRP Rabbit IgG pTyr730 Polyclonal 0
1 ABIN1711764 IHC (p) WB HRP Rabbit IgG pTyr568, pTyr570 Polyclonal 0
1 ABIN1712420 IHC (p) WB HRP Rabbit IgG pTyr823 Polyclonal 0
1 ABIN801522 IHC (p) WB HRP Rabbit IgG pSer741 Polyclonal 0
1 ABIN1388215 IHC (p) WB Biotin Rabbit IgG AA 360-405 Polyclonal 0
1 ABIN733742 IHC (p) WB HRP Rabbit IgG pTyr936 Polyclonal 0
1 ABIN671723 IHC (p) WB Biotin Rabbit IgG AA 928-964 Polyclonal 0
1 ABIN2883973 ELISA IHC IHC (p) WB Rabbit IgG pTyr703 Polyclonal 0
1 ABIN2883974 ELISA IHC IHC (p) WB Rabbit IgG pTyr936 Polyclonal 0
1 ABIN1700747 IHC (p) WB Biotin Rabbit IgG pTyr568, pTyr570 Polyclonal 0

General

Antigène Mast/stem Cell Growth Factor Receptor (KIT) Anticorps
Épitope AA 360-405
(74), (71), (69), (68), (51), (48), (35), (33), (33), (32), (27), (26), (26), (20), (19), (19), (19), (19), (19), (18), (18), (18), (18), (18), (18), (18), (18), (18), (17), (17), (17), (16), (15), (15), (15), (14), (12), (12), (11), (11), (10), (10), (10), (10), (10), (10), (10), (10), (9), (9), (9), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain, Souris, Rat (Rattus)
(1365), (477), (171), (45), (45), (38), (26), (19), (14), (5), (4), (4), (4), (3), (2), (1), (1), (1)
Hôte Lapin
(1095), (364), (161), (14), (2), (2)
Clonalité
Polyclonal
Conjugué Cet anticorp KIT est non-conjugé
(146), (134), (128), (109), (86), (76), (21), (17), (15), (14), (14), (14), (8), (8), (8), (8), (8), (8), (6), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1)
Application Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(677), (653), (446), (363), (218), (152), (119), (104), (71), (68), (55), (29), (19), (12), (11), (10), (3), (2), (2), (2), (1), (1), (1)
Pubmed 3 références disponible
Fournisseur

Détail du produit anti-KIT anticorps

Détail du antigène KIT Information d'application Stockage References for anti-KIT antibody (ABIN1387260) Images
Purification Purified by Protein A.
Immunogène KLH conjugated synthetic peptide derived from human c-Kit
Isotype IgG
Plasmids, Primers & others

Détail du antigène KIT

Détail du produit anti-KIT anticorps Information d'application Stockage References for anti-KIT antibody (ABIN1387260) Images Haut de la page
Antigène
Autre désignation C-Kit (KIT Antibody Extrait)
Sujet

Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activated KIT also transmits signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. Promotes activation of STAT family members STAT1, STAT3, STAT5A and STAT5B. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KIT signaling is modulated by protein phosphatases, and by rapid internalization and degradation of the receptor. Activated KIT promotes phosphorylation of the protein phosphatases PTPN6/SHP-1 and PTPRU, and of the transcription factors STAT1, STAT3, STAT5A and STAT5B. Promotes phosphorylation of PIK3R1, CBL, CRK (isoform Crk-II), LYN, MAPK1/ERK2 and/or MAPK3/ERK1, PLCG1, SRC and SHC1.

Subcellular location: Extracellular

Synonyms: PBT, SCFR, C-Kit, CD117, Mast/stem cell growth factor receptor Kit, Piebald trait protein, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, p145 c-kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, KIT

ID gène 3815
UniProt P10721
Pathways Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity

Information d'application

Détail du produit anti-KIT anticorps Détail du antigène KIT Stockage References for anti-KIT antibody (ABIN1387260) Images Haut de la page
Indications d'application WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
Restrictions For Research Use only

Stockage

Détail du produit anti-KIT anticorps Détail du antigène KIT Information d'application References for anti-KIT antibody (ABIN1387260) Images Haut de la page
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at -20°C
Date de péremption 12 months

References for anti-KIT antibody (ABIN1387260)

Détail du produit anti-KIT anticorps Détail du antigène KIT Information d'application Stockage Images Haut de la page
Produit citée dans:

Lin, Zhang, Li, Zou, Chen, Xue, Zhao: "Effect of electroacupuncture on gastric interstitial cells of Cajal in a rat model of diabetic gastroparesis." dans: Experimental and therapeutic medicine, Vol. 11, Issue 6, pp. 2489-2494, 2016 Méthode utilisée: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Échantillon (espèces): Rat (Rattus)).

Kennedy, Hakimjavadi, Greene, Mooney, Fitzpatrick, Collins, Loscher, Guha, Morrow, Redmond, Cahill: "Embryonic rat vascular smooth muscle cells revisited - a model for neonatal, neointimal SMC or differentiated vascular stem cells?" dans: Vascular cell, Vol. 6, Issue 1, pp. 6, 2014

Chen, Chen, Lin, Hu, Liao: "Resveratrol inhibits alpha-melanocyte-stimulating hormone signaling, viability, and invasiveness in melanoma cells." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2013, pp. 632121, 2013 (Échantillon (espèces): Mouse (Murine)).

Images

Détail du produit anti-KIT anticorps Détail du antigène KIT Information d'application Stockage References for anti-KIT antibody (ABIN1387260) Haut de la page
Images (Fournisseur)
ELISA image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 360-405) antibody (ABIN1387260) Antigen: 2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16...
Western Blotting (WB) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 360-405) antibody (ABIN1387260) Image provided by the Free Sample Program. Mouse pancreatic cancer tissue lysates pro...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 360-405) antibody (ABIN1387260) Formalin-fixed and paraffin embedded rat intestine labeled with Rabbit Anti-c-Kit Pol...
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 360-405) antibody (ABIN1387260) Image provided by One World Lab validation program. A431 cells probed with Rabbit Ant...
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 360-405) antibody (ABIN1387260) Image provided by One World Lab validation program. U138 cells probed with Rabbit Ant...