Profil protéine

The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis.

Alternative names and synonyms associated with LMTK2

• lemur tyrosine kinase 2 (LMTK2) anticorps
• lemur tyrosine kinase 2 (Lmtk2) anticorps

• 2900041G10Rik anticorps
• A330101P12Rik anticorps
• aatyk2 anticorps
• BREK anticorps
• cprk anticorps
• Afficher tous les alias de synonymes
• KPI-2 anticorps
• KPI2 anticorps
• LMR2 anticorps

Protein level used designations for LMTK2

CDK5/p35-regulated kinase , apoptosis-associated tyrosine kinase 2 , brain-enriched kinase , cyclin-dependent kinase 5/p35-regulated kinase , hBREK , kinase phosphatase inhibitor 2 , kinase/phosphatase/inhibitor 2 , serine/threonine-protein kinase KPI-2 , serine/threonine-protein kinase LMTK2