anti-Rat (Rattus) RIPK1 anticorps pour Immunohistochemistry (Frozen Sections)

Recommended RIPK1 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) Anticorps
  • RIP
  • RIP1
  • D330015H01Rik
  • Rinp
  • Rip1
  • rip1
  • ripk1
  • xRIP1beta
  • xrip1
  • receptor interacting serine/threonine kinase 1
  • receptor (TNFRSF)-interacting serine-threonine kinase 1
  • receptor interacting serine/threonine kinase 1 L homeolog
  • RIPK1
  • Ripk1
  • ripk1.L
Reactivité
Humain, Souris, Rat (Rattus)
139
44
40
8
4
3
3
1
1
Hôte
Lapin
111
31
3
Clonalité
Polyclonal
Conjugué
Cet anticorp RIPK1 est non-conjugé
6
6
5
3
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
115
57
56
26
24
16
5
5
4
2
2
1
1
Options
Fournisseur
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N° du produit (Fournisseur)
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N° du produit ABIN127073
$ 429.00
Plus shipping costs $45.00

General

Antigène Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) Anticorps
Reactivité Humain, Souris, Rat (Rattus)
(139), (44), (40), (8), (4), (3), (3), (1), (1)
Hôte Lapin
(111), (31), (3)
Clonalité
Polyclonal
Conjugué Cet anticorp RIPK1 est non-conjugé
(6), (6), (5), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(115), (57), (56), (26), (24), (16), (5), (5), (4), (2), (2), (1), (1)
Pubmed 2 références disponible
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Détail du produit anti-RIPK1 anticorps

Détail du antigène RIPK1 Information d'application Stockage References for anti-RIPK1 antibody (ABIN127073) Images
Specificité The antibody detects 74 kDa RIP in Western blot analysis.
Réactivité croisée (Details) Species reactivity (tested):Human, Mouse and Rat.
Purification Affinity Chromatography.
Immunogène Synthetic peptide surrounding amino acid 645 of Human RIP
Plasmids, Primers & others

Détail du antigène RIPK1

Détail du produit anti-RIPK1 anticorps Information d'application Stockage References for anti-RIPK1 antibody (ABIN127073) Images Haut de la page
Antigène
Autre désignation RIP (RIPK1 Antibody Extrait)
Sujet RIP (Receptor Interacting Protein) is a 74 kDa Ser/Thr kinase which interacts with CD95 (Fas/Apo1) receptor and the tumor necrosis factor receptor (TNFR1). It is a cell death domain adapter protein which can bind to the adapter proteins TRADD, RAID, and TRAF2. RIP contains an N-terminal region with homology to protein kinase, an intermediate domain capable of association with MAPKKK and a C-terminal region containing an intracellular death domain motif. RIP activates both p38 MAP kinase and SAPK families. In vitro, RIP induces apoptosis, as well as SAPK/JNK and NF-kB activation. RIP possesses kinase activity as it autophosphorylates itself on serine and threonine residues.Synonyms: Cell death protein RIP, RIPK1, Receptor-Interacting Protein, Receptor-interacting serine/threonine-protein kinase 1, Serine/threonine-protein kinase RIP
ID gène 8737
NCBI Accession NP_003795
UniProt Q13546
Pathways Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Signalisation TLR, Activation of Innate immune Response, Inositol Metabolic Process, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling

Information d'application

Détail du produit anti-RIPK1 anticorps Détail du antigène RIPK1 Stockage References for anti-RIPK1 antibody (ABIN127073) Images Haut de la page
Indications d'application Western Blot: 2-6 μg/mL. Immunoprecipitation. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Stockage

Détail du produit anti-RIPK1 anticorps Détail du antigène RIPK1 Information d'application References for anti-RIPK1 antibody (ABIN127073) Images Haut de la page
Concentration 0.5 mg/mL
Buffer PBS, pH 7.2, containing 30 % Glycerol, 0.5 % BSA as stabilizer and 0.01 % Thimerosal as preservative.
Agent conservateur Thimerosal (Merthiolate)
Précaution d'utilisation This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock -20 °C/-80 °C
Stockage commentaire Store the antibody undiluted at -20 °C or (in aliquots) at -70 °C for long term storage.

References for anti-RIPK1 antibody (ABIN127073)

Détail du produit anti-RIPK1 anticorps Détail du antigène RIPK1 Information d'application Stockage Images Haut de la page
Background publications

Hsu, Huang, Shu, Baichwal, Goeddel: "TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex." dans: Immunity, Vol. 4, Issue 4, pp. 387-96, 1996

Stanger, Leder, Lee, Kim, Seed: "RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death." dans: Cell, Vol. 81, Issue 4, pp. 513-23, 1995