Aperçu des produits pour anti-ROR2 (ROR2) Anticorps

Human Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) interaction partners

1. ROR1 (Montrer ROR1 Anticorps) and ROR2 play distinct roles in endometrial cancer. ROR1 (Montrer ROR1 Anticorps) may promote tumor progression, while ROR2 may act as a tumor suppressor in endometrioid endometrial cancer.

2. Wnt5a (Montrer WNT5A Anticorps)-Ror2 signaling enhanced tongue SCC (Montrer CYP11A1 Anticorps) cell aggressiveness and promoted production of MMP-2 (Montrer MMP2 Anticorps) following DeltaNp63beta-mediated EMT (Montrer ITK Anticorps)

3. In squamous/adenosquamous carcinoma and adenocarcinoma of the gallbladder positive ROR2 or WNT5a (Montrer WNT5A Anticorps) expression is generally associated with a poor prognosis.

4. Wnt5a (Montrer WNT5A Anticorps) suppressed osteoblastic differentiation through Ror2/JNK (Montrer MAPK8 Anticorps) signaling in periodontal ligament stem cell-like cells.

5. Data show that receptor tyrosine kinase-like orphan receptor 2 (ROR2) is epigenetically silenced by promoter hypermethylation in colorectal cancer cell lines and in early stages of colorectal neoplasia tissue.

6. WNT5A (Montrer WNT5A Anticorps) and ROR2 are induced by inflammatory mediators through NF-kB and STAT3 (Montrer STAT3 Anticorps) transcription factors, and are involved in the migration of human ovarian cancer cell line SKOV-3.

7. On these bases, we identified that miR (Montrer MLXIP Anticorps)-208b targets receptor tyrosine kinase-like orphan receptor 2 gene by which miR (Montrer MLXIP Anticorps)-208b can regulate the development of osteosarcoma.

8. Our findings suggest that receptor tyrosine kinase-like orphan receptor 2 may be an important regulator of epithelial-mesenchymal transition, primarily regulated the non-canonical Wnt (Montrer WNT2 Anticorps) signaling pathway in ovarian cancer cells, and may display a promising therapeutic target for ovarian cancer.

9. Knockdown of Ror2 expression in renal cell carcinoma (Montrer MOK Anticorps) cells significantly reduced cell proliferation and induced apoptosis.

10. found no association between ROR2 staining and poor patient survival

Mouse (Murine) Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) interaction partners

1. The Ror2-mediated signaling might be activated in response to tissue damage and associated with progression of fibrosis in the submandibular gland (SMG (Montrer SNRPG Anticorps)).

2. Ror2 plays a critical role in regulating the cell cycle progression of reactive astrocytes following brain injury

3. we uncovered cell state plasticity and adhesion dynamics regulated by Ror2, which influenced Ras Homology Family Member A (Montrer CXCL14 Anticorps) (RhoA (Montrer RHOA Anticorps)) and Rho-Associated Coiled-Coil Kinase 1 (ROCK1 (Montrer ROCK1 Anticorps)) activity downstream of Dishevelled-2 (Dvl2 (Montrer DVL2 Anticorps)).

4. Here, the study of two Ror2 mutants connects aberrant germ cell migration to defects in meiosis and supports the diffusion model of meiotic entry.

5. Although Ror1 (Montrer ROR1 Anticorps)-mutant mice show no apparent defects in ureteric bud (UB) formation, Ror1 (Montrer ROR1 Anticorps); Ror2-double-mutant mice exhibit either defects in UB outgrowth and branching morphogenesis, associated with the loss of the MM from the UB domain, or ectopic formation of the UB.

6. The Wnt5a (Montrer WNT5A Anticorps)-Ror2 axis promotes the signaling circuit between interleukin-12 and interferon-gamma (Montrer IFNG Anticorps) in colitis

7. Non-canonical Wnt5a (Montrer WNT5A Anticorps)/Ror2 signaling regulates kidney morphogenesis by controlling intermediate mesoderm extension.

8. Ror2 plays an important role in mammary gland development in mice.

9. The activation of Wnt5a (Montrer WNT5A Anticorps)-Ror2 signaling in epithelial cells undergoing epithelial-to-mesenchymal transition (EMT (Montrer ITK Anticorps)) may play an important role in disrupting TBM via MMP-2 (Montrer MMP2 Anticorps) induction during renal fibrosis.

10. The results indicate an important role of Wnt5a (Montrer WNT5A Anticorps)-Ror2 signaling in morphogenesis of the metanephric mesenchyme to ensure proper epithelial tubular formation of the ureteric bud required for kidney development.

Xenopus laevis Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) interaction partners

1. In the Xenopus embryo, Ptk7 (Montrer PTK7 Anticorps) functionally interacts with Ror2 to regulate protocadherin papc (Montrer PCDH8 Anticorps) expression and morphogenesis.

2. Xenopus adult stem cells originate from the larval absorptive cells expressing Ror2, which require Wnt5a (Montrer WNT5A Anticorps)/Ror2 signaling for their dedifferentiation accompanied by changes in cell morphology.

3. Data show that PAPC (Montrer PCDH8 Anticorps) signaling via RhoA (Montrer RHOA Anticorps) and Wnt5a (Montrer WNT5A Anticorps)/Ror2 activity are required to keep cells aligned in apical-basal orientation during invagination of the ear placode.

4. Transcriptional regulation of XPAPC (Montrer PCDH8 Anticorps) by XWnt-5A (Montrer WNT5A Anticorps) requires the receptor tyrosine kinase Ror2.

5. demonstrated that this anti-canonical Wnt (Montrer WNT2 Anticorps) activity of Del1 is dependent on the Ror2 pathway, which is activated by the non-canonical Wnt (Montrer WNT2 Anticorps) ligands