Aperçu des produits pour anti-SHC3 (SHC3) Anticorps

Full name:: anti-SHC (Src Homology 2 Domain Containing) Transforming Protein 3 Anticorps (SHC3)

Chez www.anticorps-enligne.fr sont 59 SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) Anticorps de 16 de différents fournisseurs disponibles. De plus, nous expédions SHC3 Protéines (6) et beaucoup plus de produits pour cette protéine. Un total de 74 SHC3 produits sont actuellement listés.

Synonymes:: N-Shc, NSHC, Rai, ShcC

afficher tous les anticorps	Gène	GeneID	UniProt
	SHC3	53358	Q92529
	SHC3	114858
	SHC3	20418	Q61120
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anti-Human SHC3 Anticorps:

anti-Rat (Rattus) SHC3 Anticorps:

anti-Mouse (Murine) SHC3 Anticorps:

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Pathways pertinentes pour anti-SHC3 Anticorps

Neurotrophin Signaling Pathway

Plus produit pour SHC3 Anticorps

anti-SHC3 Anticorps mieux référencés

Human Polyclonal SHC3 Primary Antibody pour WB - ABIN2801960 : Liu, Meakin: ShcB and ShcC activation by the Trk family of receptor tyrosine kinases. dans The Journal of biological chemistry 2002 (PubMed)
Show all 4 Pubmed References

Plus d’anticorps contre SHC3 partenaires d’interaction

Human SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) interaction partners

High SHC3 expression is associated with glioblastoma.
Rai (ShcC/N-Shc), a member of the family of Shc (Montrer SHC1 Anticorps)-like adaptor proteins, as a new regulator of migration of normal and cancer stem/progenitor cells.
Polymorphism in RAI (Montrer RNH1 Anticorps) and CD3EAP (Montrer CD3EAP Anticorps) are associated with outcome of myeloma patients treated with high dose treatment.
amplification of SHC3 and EDG3 (Montrer S1PR3 Anticorps) genes suggests that the two proteins co-operate and are important for ependymomas in vivo.
Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc (Montrer SHC1 Anticorps).
ALK-ShcC signal activation, possibly caused by co-amplification with the N-myc gene, might give additional effects on malignant tumor progression of neuroblastoma.ShcC is a potent substrate of the activated ALK kinase.
The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret (Montrer RET Anticorps) to the phosphatidylinositol 3-kinase/Akt (Montrer AKT1 Anticorps) signaling pathway.
ShcC has phosphotyrosine-dependent and -independent functions in neuroblastoma (Montrer ARHGEF16 Anticorps) cells
The inappropriate in vivo expression of Shc3 in high-grade glioma may contribute to the survival of the cancer cells.
data suggest that RAI (ShcC/H-Shc (Montrer SHC1 Anticorps))is a critical substrate for RET (Montrer RET Anticorps) oncoproteins in thyroid carcinomas

Mouse (Murine) SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) interaction partners

The results provide evidence that Rai/ShcC plays opposite roles in Th17 cell differentiation and astrocyte activation
Rai (ShcC/N-Shc), a member of the family of Shc (Montrer SHC1 Anticorps)-like adaptor proteins, as a new regulator of migration of normal and cancer stem/progenitor cells.
Rai interferes with the TCR signaling cascade one of the earliest steps--recruitment of the initiating kinase ZAP-70 (Montrer ZAP70 Anticorps) to the phosphorylated subunit of the TCR/CD3 (Montrer CD3E Anticorps) complex.
TrkB (Montrer NTRK2 Anticorps)-mediated ERK1/2 activation is impaired in huntingtin (Montrer HTT Anticorps) knock-in striatal cells involves reduced p52 (Montrer GTF2H4 Anticorps)/p46 (Montrer POLDIP3 Anticorps) Shc (Montrer SHC1 Anticorps) expression
Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc (Montrer SHC1 Anticorps).
binds the Trk (Montrer NTRK1 Anticorps) receptors in a phosphotyrosine-dependent manner via their N-terminal phosphotyrosine binding domain
Rai has a functional neuroprotective role in brain injury, with possible implications in the treatment of stroke
ShcC mediates TrkB (Montrer NTRK2 Anticorps)-Ras/MAPK (Montrer MAPK1 Anticorps) signaling & regulates NMDA receptor function in the hippocampus via interaction with phosphotyrosines on the receptor subunits. It serves as a modulator of hippocampal synaptic plasticity underlying learning & memory.
ShcC has phosphotyrosine-dependent and -independent functions in neuroblastoma (Montrer ARHGEF16 Anticorps) cells
Expressed in T and B cells; loss of Rai results in breaking of immunological tolerance and development of systemic autoimmunity.

SHC3 profil antigène

Antigen Summary

may be involved in brain-derived neurotrophic factor signalling during retinal development

Alternative names and synonyms associated with SHC3

SHC adaptor protein 3 (SHC3) anticorps
SHC adaptor protein 3 (Shc3) anticorps
src homology 2 domain-containing transforming protein C3 (Shc3) anticorps

N-Shc anticorps
NSHC anticorps
Rai anticorps
ShcC anticorps

Protein level used designations for SHC3

SH2 domain protein C3 , SHC-transforming protein 3 , SHC-transforming protein C , neuronal Shc , protein Rai , src homology 2 domain-containing transforming protein C3 , src homology 2 domain-containing-transforming protein C3 , N-Shc

GENE ID	SPECIES
100061926	Equus caballus
53358	Homo sapiens
114858	Rattus norvegicus
476352	Canis lupus familiaris
20418	Mus musculus

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Show all anti-SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) Anticorps with Pubmed References

Human SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) interaction partners

Mouse (Murine) SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) interaction partners

Antigen Summary

Alternative names and synonyms associated with SHC3

Protein level used designations for SHC3