anti-Rat (Rattus) VEGFC anticorps pour Enzyme Immunoassay

Recommended VEGFC Antibody

Antigène
Vascular Endothelial Growth Factor C (VEGFC) Anticorps
  • VEGFC
  • vegf-c
  • xvegf-c
  • Flt4-L
  • VRP
  • AW228853
  • VEGF-C
  • vascular endothelial growth factor c
  • vascular endothelial growth factor C
  • vascular endothelial growth factor C S homeolog
  • vegfc
  • VEGFC
  • vegfc.S
  • Vegfc
Reactivité
Humain, Rat (Rattus)
196
98
64
3
3
2
2
2
1
1
1
1
Hôte
Souris
198
57
9
1
1
1
Clonalité
Monoclonal
Conjugué
Cet anticorp VEGFC est non-conjugé
29
22
16
9
8
8
3
3
3
3
3
3
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
211
121
112
24
24
17
17
13
9
8
4
3
1
Options
N° du produit ABIN360868
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
1 ABIN115678 EIA IP Rabbit Polyclonal 1
1 ABIN115679 EIA IP Rabbit Polyclonal 0
1 ABIN5540710 EIA Biotin Rabbit IgG AA 101-221 Polyclonal 0

General

Antigène Vascular Endothelial Growth Factor C (VEGFC) Anticorps
Reactivité Humain, Rat (Rattus)
(196), (98), (64), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Hôte Souris
(198), (57), (9), (1), (1), (1)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp VEGFC est non-conjugé
(29), (22), (16), (9), (8), (8), (3), (3), (3), (3), (3), (3), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(211), (121), (112), (24), (24), (17), (17), (13), (9), (8), (4), (3), (1)
Pubmed 2 références disponible
Fournisseur

Détail du produit anti-VEGFC anticorps

Détail du antigène VEGFC Information d'application Stockage References for anti-VEGFC antibody (ABIN360868) Images
Specificité This antibody detects VEGF-C in Western Blots. No cross-reactivity is shown with VEGF-A.
Purification Protein G Affinity Chromatography
Immunogène Recombinant Human VEGF-C protein (Cat.-No AR01001PU-N)
Clone 107F10
Isotype IgG2a
Plasmids, Primers & others

Détail du antigène VEGFC

Détail du produit anti-VEGFC anticorps Information d'application Stockage References for anti-VEGFC antibody (ABIN360868) Images Haut de la page
Antigène
Autre désignation VEGF-C / Flt4-L (VEGFC Antibody Extrait)
Sujet VEGF-C, also known as Vascular Endothelial Growth Factor Related Protein (VRP), is a recently discovered VEGF growth factor family member that is most closely related to VEGF-D. The human VEGF-C cDNA encodes a pre-pro-protein of 416 amino acids residues. It is almost identical to the mouse VEGF-C protein. Similar to VEGF-D, VEGF-C has a VEGF homology domain spanning the middle third of the precursor molecule and long N- and C-terminal extensions. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. Recombinant human VEGF-C, lacking the N- and C-terminal extensions and containing only the middle VEGF homology domain, forms primarily non-covalently linked dimers. This protein is a ligand for both VEGFR-2/KDR and VEGFR-3/FLT-4. Since VEGFR-3 is strongly expressed in lymphatic endothelial cells, it has been postulated that VEGF-C is involved in the regulation of the growth and/or differentiation of lymphatic endothelium. Although recombinant human VEGF-C is also a mitogen for vascular endothelial cells, it is much less potent than VEGF-A. The recombinant human VEGF-C contains 115 amino acids residues and was fused to a His-tag (6x His) at the C-terminal end. As a result of glycosylation VEGF-C migrates as an 18-24 kDa protein in SDS-PAGE under reducing conditions.Synonyms: Flt4 ligand, VEGFC, VRP, Vascular endothelial growth factor C, Vascular endothelial growth factor-related protein
ID gène 7424
NCBI Accession NP_005420
UniProt P49767
Pathways Signalisation RTK, Signaling Events mediated by VEGFR1 and VEGFR2

Information d'application

Détail du produit anti-VEGFC anticorps Détail du antigène VEGFC Stockage References for anti-VEGFC antibody (ABIN360868) Images Haut de la page
Indications d'application Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Stockage

Détail du produit anti-VEGFC anticorps Détail du antigène VEGFC Information d'application References for anti-VEGFC antibody (ABIN360868) Images Haut de la page
Reconstitution Restore in sterile water to a concentration of 0.1-1.0 mg/mL. Centrifuge vial prior to opening.
Buffer PBS without preservatives or stabilizers
Agent conservateur Without preservative
Conseil sur la manipulation Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Stock 4 °C/-20 °C
Stockage commentaire Prior to reconstitution store at 2-8 °C. Following reconstitution store at -20 °C. This product should be stored undiluted.

References for anti-VEGFC antibody (ABIN360868)

Détail du produit anti-VEGFC anticorps Détail du antigène VEGFC Information d'application Stockage Images Haut de la page
Background publications

Olofsson, Jeltsch, Eriksson, Alitalo: "Current biology of VEGF-B and VEGF-C." dans: Current opinion in biotechnology, Vol. 10, Issue 6, pp. 528-35, 2000

Joukov, Pajusola, Kaipainen, Chilov, Lahtinen, Kukk, Saksela, Kalkkinen, Alitalo: "A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases." dans: The EMBO journal, Vol. 15, Issue 2, pp. 290-98, 1996