anti-Souris CREB1 anticorps pour Electrophoretic Mobility-Shift Assay

Recommended CREB1 Antibody

Antigène
cAMP Responsive Element Binding Protein 1 (CREB1) Anticorps
  • creb
  • CREB1
  • Creb1
  • CREB
  • 2310001E10Rik
  • 3526402H21Rik
  • AV083133
  • Creb
  • Creb-1
  • creb1
  • zgc:55598
  • cAMP responsive element binding protein 1
  • cAMP responsive element binding protein
  • cAMP responsive element binding protein 1 S homeolog
  • cAMP responsive element binding protein 1a
  • CREB1
  • creb1
  • CREB
  • Creb1
  • creb1.S
  • creb1a
Épitope
N-Term
133
48
47
29
20
19
17
15
11
11
10
9
8
8
8
7
6
5
4
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
626
392
353
43
38
36
34
27
23
23
17
15
14
7
7
7
1
1
1
1
1
Hôte
Lapin
555
73
13
1
Clonalité
Polyclonal
Conjugué
Cet anticorp CREB1 est non-conjugé
26
15
15
14
13
13
13
13
13
8
7
6
3
3
3
3
3
1
Application
Electrophoretic Mobility-Shift Assay (EMSA), Enzyme Immunoassay (EIA), Immunoprecipitation (IP), Western Blotting (WB)
457
270
224
97
85
56
42
41
27
18
10
10
5
3
2
2
2
Options

Images

N° du produit ABIN116948
$ 594.00
Plus shipping costs $45.00

General

Antigène cAMP Responsive Element Binding Protein 1 (CREB1) Anticorps
Épitope N-Term
(133), (48), (47), (29), (20), (19), (17), (15), (11), (11), (10), (9), (8), (8), (8), (7), (6), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain, Souris, Rat (Rattus)
(626), (392), (353), (43), (38), (36), (34), (27), (23), (23), (17), (15), (14), (7), (7), (7), (1), (1), (1), (1), (1)
Hôte Lapin
(555), (73), (13), (1)
Clonalité
Polyclonal
Conjugué Cet anticorp CREB1 est non-conjugé
(26), (15), (15), (14), (13), (13), (13), (13), (13), (8), (7), (6), (3), (3), (3), (3), (3), (1)
Application Electrophoretic Mobility-Shift Assay (EMSA), Enzyme Immunoassay (EIA), Immunoprecipitation (IP), Western Blotting (WB)
(457), (270), (224), (97), (85), (56), (42), (41), (27), (18), (10), (10), (5), (3), (2), (2), (2)
Pubmed 1 référence disponible
Fournisseur

Détail du produit anti-CREB1 anticorps

Détail du antigène CREB1 Information d'application Stockage References for anti-CREB1 antibody (ABIN116948) Images
Specificité This product was prepared from monospecific antiserum by delipidation and Immunoadsorption against an E.coli lysate immobilized on agarose beads. This antibody may react non-specifically with other proteins. A partial cross-reactivity is observed against CREM-1 protein.
Immunogène CREB-1 (p43) peptide corresponding to a region near the N-terminus of the Human protein conjugated to Keyhole Limpet Hemocyanin (KLH).
Plasmids, Primers & others

Détail du antigène CREB1

Détail du produit anti-CREB1 anticorps Information d'application Stockage References for anti-CREB1 antibody (ABIN116948) Images Haut de la page
Antigène
Autre désignation CREB1 (CREB1 Antibody Extrait)
Sujet Cyclic AMP Response Element Binding protein (CREB) is a basic / leucine zipper transcription factor that binds the cyclic AMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth and neurotrophic factors. Activation of CREB is dependent upon the phosphorylation of serine 133. Phosphorylation occurs via p44 / 42 MAP kinase and p90RSK and also via p38 MAP kinase and MSK 1. Although CREB will bind DNA independent of its phosphorylation state, only the phosphorylated form is competent as a transcription factor. CREB binding protein (CBP), a transcriptional coactivator that directly interacts with CREB, binds to CREB in the region of serine 133. CREB appears to play an important role in learning and memory. CREB knock out mice show diminished learning ability.Synonyms: CREB-1, Cyclic AMP-responsive element-binding protein 1, cAMP-responsive element-binding protein 1
ID gène 1385
NCBI Accession NP_004370
UniProt P16220
Pathways Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation

Information d'application

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Stockage References for anti-CREB1 antibody (ABIN116948) Images Haut de la page
Indications d'application Western Blot: This antibody was assayed against a lysate of 1 x 10^6 Raji B cells byImmunoblot and found to be reactive against CREB-1 (p43), showing a 46 kDa band at adilution of 1/500-1/1,000 followed by reaction with Peroxidase conjugated anti-Rabbit IgG(H&L) [Goat] (Cat#R1364HRP)ELISA: 1/5,000-1/25,000. Immunoprecipitation. Gelshift: This antibody was tested in Gel Supershift Assay and found to be reactive againstCREB-1 (p43) using 0.5-1.0 μL per assay.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Stockage

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Information d'application References for anti-CREB1 antibody (ABIN116948) Images Haut de la page
Format Liquid
Concentration 2.56 mg/mL (by UV absorbance at 280 nm)
Buffer 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide, None
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store lyophilized (preferably in a desiccator) at 2-8 °C and reconstituted (in aliquots) at -20 °C.

References for anti-CREB1 antibody (ABIN116948)

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Information d'application Stockage Images Haut de la page
Background publications

Moreno, Beresford, Louis-Plence, Morris, Boss: "CREB regulates MHC class II expression in a CIITA-dependent manner." dans: Immunity, Vol. 10, Issue 2, pp. 143-51, 1999

Images

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Information d'application Stockage References for anti-CREB1 antibody (ABIN116948) Haut de la page
Images (Fournisseur)
Western Blotting (WB) image for anti-cAMP Responsive Element Binding Protein 1 (CREB1) (N-Term) antibody (ABIN116948) Anti-CREB is shown to detect CREB-1 present in Raji B cell nuclear extract lysates. D...