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anti-Human EPO Anticorps:
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Human Polyclonal EPO Primary Antibody pour IF (p), IHC (p) - ABIN679718
DeNiro, Al-Mohanna: Nuclear factor kappa-B signaling is integral to ocular neovascularization in ischemia-independent microenvironment. dans PLoS ONE 2014
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Human Monoclonal EPO Primary Antibody pour ICC, ELISA - ABIN969109
Hirschler-Laszkiewicz, Tong, Conrad, Zhang, Flint, Barber, Barber, Cheung, Miller: TRPC3 activation by erythropoietin is modulated by TRPC6. dans The Journal of biological chemistry 2009
Human Monoclonal EPO Primary Antibody pour ELISA, WB - ABIN515362
Wang, Dou, Lü, Liu: Immuno-magnetic beads-based extraction-capillary zone electrophoresis-deep UV laser-induced fluorescence analysis of erythropoietin. dans Journal of chromatography. A 2012
Human Monoclonal EPO Primary Antibody pour WB - ABIN2473499
Gladun: [Theoretical problems of legal regulations of the reorganization of public health in the USSR]. dans Sovetskoe zdravookhranenie / Ministerstvo zdravookhranenii?a SSSR 1991
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Human Polyclonal EPO Primary Antibody pour ELISA, WB - ABIN153425
Ryou, Choudhury, Li, Winters, Yuan, Liu, Yang: Methylene blue-induced neuronal protective mechanism against hypoxia-reoxygenation stress. dans Neuroscience 2015
Data show that erythropoietin (EPO) mRNA was upregulated in the lung, from the metamorphic climax (stage 60) onward.
Pro-inflammatory proteins S100A9 (Montrer S100A9 Anticorps) and tumor necrosis factor-alpha (Montrer TNF Anticorps) suppress erythropoietin elaboration in myelodysplastic syndromes
Results suggest an interplay of the production and action of hydrogen sulfide (Montrer SQRDL Anticorps) during hypoxia with subsequent erythropoietin production regulated by HIF-1alpha (Montrer HIF1A Anticorps) and HIF-2alpha (Montrer EPAS1 Anticorps).
EPO levels in the coronary artery disease (CAD (Montrer CAD Anticorps)) group were higher than those in the non-CAD (Montrer CAD Anticorps) group. The correlation between red cell distribution width and EPO levels was statistically significant among CAD (Montrer CAD Anticorps) patients.
CD133(+) cells contributed to the local production of erythropoietin, as observed by detection of circulating human erythropoietin. CD133(+) cells appear therefore an effective source for cell repair, able to restore renal functions, including erythropoietin release, and to limit long term maldifferentiation and fibrosis.
Circulating anti-EPO are detected in a significant proportion of treatment-naive HCV-infected patients and are independently associated with anemia, suggesting a further implication of autoimmunity in the pathophysiology of HCV-related anemia.
the T allele of SNP rs60684937 located at 67,419,130 bp on chromosome 17 was associated with increased plasma EPO and a relatively increased expression of a non-coding transcript of PRKAR1A (Montrer PRKAR1A Anticorps) in sickle cell disease patients
study describes a gain-of-function variant in EPO in an extended kindred with familial erythrocytosis, including 10 affected family members in four generations; this mutation, a single-nucleotide deletion (c.32delG), introduces a frameshift in exon 2
Here, using zebrafish, murine, and human models, the authors show that erythropoietin (EPO) signaling, together with the GATA1 (Montrer GATA1 Anticorps) transcriptional target, AKAP10 (Montrer AKAP10 Anticorps), regulates heme biosynthesis during erythropoiesis at the outer mitochondrial membrane.
Reduction in central venous blood pressure prompts an increase in plasma EPO concentration independent of hemoconcentration and hence suggests CVP per se as an acute regulator of EPO synthesis
EPO (7q22) and SEC-61 (Montrer SEC61A1 Anticorps)(7p11) emerged as new candidate genes susceptible to genetic losses with 57.7% deletions identified in regions on chromosome 7.
Compared to wild type (WT) animals, Epo-TAg(h) female mice exhibited higher ventilation in hypoxia. However, when data were separated into luteal and follicular phases of the estrous cycle, basal ventilation and hypoxic ventilation were not different in both mice strains. Experiments with mifepristone (progesterone receptor (Montrer PGR Anticorps) antagonist) suggest that this effect is independent from the respiratory effects of progesterone.
this study revealed a new mechanism wherein EPO alleviates hepatic steatosis by activating autophagy via SIRT1 (Montrer SIRT1 Anticorps)-dependent deacetylation of LC3 (Montrer MAP1LC3A Anticorps).
This study suggests that moderate elevated brain Epo levels provide clinically significant neuroprotection in experimental autoimmune encephalomyelitis without modulation of the immune response making a significant contribution.
The functional role of signal cascades involved in the production of erythropoietin by T cells is determined by the stage of the common adaptation syndrome.
A novel biological pathway has been discovered of soluble biglycan (Montrer BGN Anticorps) inducing HIF-2alpha (Montrer EPAS1 Anticorps) protein stabilization and Epo production presumably in an oxygen-independent manner, ultimately giving rise to secondary polycythemia.
data identify the PHD2 (Montrer EGLN1 Anticorps):HIF-2alpha:EPO axis as a so far unknown regulator of osteohematology by controlling bone homeostasis.
these data provide strong evidence for a role for G-CSF (Montrer CSF3 Anticorps) in the development of ACI after burn injury through suppression of EPO signaling in bone marrow erythroid cells.
Data indicated the possible involvement of Jak2 (Montrer JAK2 Anticorps)/STAT3 (Montrer STAT3 Anticorps)/STAT6 (Montrer STAT6 Anticorps) pathway in the augmentation of EPO on M2 polarization. These results improved the understanding of the immunoregulatory capacity of EPO on macrophages, which might optimize the therapeutic modalities of EPO.
The lack of effect of erythropoietin on hepcidin (Montrer HAMP Anticorps) expression in mask mice can not be explained by changes in erythroferrone synthesis, as splenic erythroferrone content increased after erythropoietin administration in both C57BL/6 and mask mice.
EPO expression in myoblasts and myotubes is increased by hypoxia and exercise
EPO might play a role as a survival factor or as a mitogen in developing cartilage tissue.
Pyruvate-fortified cardioplegia evokes myocardial erythropoietin signaling in swine undergoing cardiopulmonary bypass.
A single intramuscular injection of recombinant adeno (Montrer ADORA2A Anticorps)-associated virus carrying mutant Epo (R76E) preserves retinal ganglion cells and visual function in glaucomatous mice.
The zebrafish epo cDNA was cloned and the expression of zepo mRNA was mainly in the heart and liver.
characterization of zebrafish epo and epor (Montrer EPOR Anticorps) demonstrates the conservation of an ancient program that ensures proper red blood cell numbers during normal homeostasis and under hypoxic conditions
This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.