Aperçu des produits pour anti-IL12RB2 (IL12RB2) Anticorps

Full name:: anti-Interleukin 12 Receptor, beta 2 Anticorps (IL12RB2)

Chez www.anticorps-enligne.fr sont 95 Interleukin 12 Receptor, beta 2 (IL12RB2) Anticorps de 18 de différents fournisseurs disponibles. De plus, nous expédions IL12RB2 Protéines (21) et IL12RB2 Kits (10) et beaucoup plus de produits pour cette protéine. Un total de 131 IL12RB2 produits sont actuellement listés.

Synonymes:: A930027I18Rik, Ifnm, IL-12RB2, IL12RB2

afficher tous les anticorps	Gène	GeneID	UniProt
	IL12RB2	16162	P97378
	IL12RB2	171334
	IL12RB2	3595	Q99665
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Pathways pertinentes pour anti-IL12RB2 Anticorps

Signalistation JAK/STAT

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anti-IL12RB2 Anticorps mieux référencés

Human Monoclonal IL12RB2 Primary Antibody pour FACS - ABIN4897167 : Nguyen, Frye, Zbesko, Stepanovic, Hayes, Urzua, Serrano, Beach, Doyle: Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue. dans Acta neuropathologica communications 2016 (PubMed)
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Human Monoclonal IL12RB2 Primary Antibody pour FACS - ABIN4897173 : Cunningham, Cardwell, Guan, Teixeiro, Daniels: POSH Regulates CD4+ T Cell Differentiation and Survival. dans Journal of immunology (Baltimore, Md. : 1950) 2016 (PubMed)
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Human Polyclonal IL12RB2 Primary Antibody pour IF (p), IHC (p) - ABIN747878 : Filková, Vernerová, Hulejová, Prajzlerová, Veigl, Pavelka, Vencovský, Šenolt: Pro-inflammatory effects of interleukin-35 in rheumatoid arthritis. dans Cytokine 2015 (PubMed)

Plus d’anticorps contre IL12RB2 partenaires d’interaction

Mouse (Murine) Interleukin 12 Receptor, beta 2 (IL12RB2) interaction partners

These results provide a new pathway of Th1 (Montrer HAND1 Anticorps) response regulation where IL-12 (Montrer IL12A Anticorps) secreted by dendritic cellss is consumed by a sub-population of IL-12Rbeta2-expressing Treg cells.
in neonatal mice, IL-12 (Montrer IL12A Anticorps) uses IL-12Rbeta2 to counter IL-13Ralpha1 expression in addition to promoting Th1 (Montrer HAND1 Anticorps) differentiation
Data indicate that delayed induction of the IL-12Rbeta2 receptor component after STAT1 (Montrer STAT1 Anticorps) activation helped ensure that Treg cells do not readily complete STAT4 (Montrer STAT4 Anticorps)-dependent Th1 (Montrer HAND1 Anticorps) cell development and lose their ability to suppress effector T cell proliferation.
Signaling through the IL-35 receptor required the transcription factors STAT1 (Montrer STAT1 Anticorps) and STAT4 (Montrer STAT4 Anticorps).
Data show that T(H)1 differentiation was impaired in Il2 (Montrer IL2 Anticorps)(-/-) T cells but was restored by IL-12Rbeta2 expression.
gamma rays cause a decrease in IFN-gamma (Montrer IFNG Anticorps), IL-12p70, IL-12 (Montrer IL12A Anticorps) receptor beta2, and STAT4 (Montrer STAT4 Anticorps) and an increase in IL-4 (Montrer IL4 Anticorps) in natural killer cells
Freshly isolated ex vivo T helper (Th)17 cells display restricted expression from Il12rb2 due to the presence of repressive chromatin remodeling.
T-bet mediates STAT1 (Montrer STAT1 Anticorps)-dependent processes of T(H)1 development, including the induction of IL-12Rbeta2.
NO activates soluble guanylyl cyclase, leading to the up-regulation of cGMP, which selectively induces the expression of IL-12 (Montrer IL12A Anticorps) receptor beta2.
Contrary to the expectation that the absence of IL-12RB2 would protect from experimental autoimmune encephalitis, IL-12RB2-deficient mice develop earlier and more severe disease, with extensive demyelination and central nervous system inflammation.

Human Interleukin 12 Receptor, beta 2 (IL12RB2) interaction partners

Tumor cell differentiation is associated with TILs' expression of IL-12Rbeta2, and an IL-12Rbeta2(+) TIL (Montrer TLR1 Anticorps) ratio >/=35%) indicates favorable prognosis in LC
inhibition of the H3K27 demethylase (Montrer MBD2 Anticorps) JMJD3 (Montrer Kdm6b Anticorps) in naive CD4 (Montrer CD4 Anticorps) T cells demonstrates how critically important molecules required for T cell differentiation, such as JAK2 (Montrer JAK2 Anticorps) and IL12RB2, are regulated by H3K27me3.
this study identified susceptibility single nucleotide polymorphisms in IL12RB2 with Behcet's disease in Han Chinese
In ankylosing spondylitis, conditional analysis identified rs11209032 as the probable causal single-nucleotide polymorphism within a 1.14 kb putative enhancer between IL23R (Montrer IL23R Anticorps) and IL12RB2. The rs11209032 single-nucleotide polymorphism downstream of IL23R (Montrer IL23R Anticorps) forms part of an enhancer, allelic variation of which may influence Th1 (Montrer TH1L Anticorps)-cell numbers.
The results of this case-control study suggest that IL-12A (Montrer IL12A Anticorps), IL-12B (Montrer IL12B Anticorps), IL12RB1 (Montrer IL12RB1 Anticorps), IL12RB2 and IL23R (Montrer IL23R Anticorps) make no genetic contribution to the susceptibility of Takayasu arteritis in Chinese populations
study confirmed the relationship of IL12RB2 polymorphisms with primary biliary cholangitis (PBC (Montrer DLAT Anticorps)) susceptibility; provided evidence that IL12RB2 polymorphisms are associated with liver cirrhosis and an increased concentration of disease-specific anti-mitochondrial antibodies in sera of PBC (Montrer DLAT Anticorps) patients
this study shows that single nucleotide polymorphisms of the IL23R-IL12RB2 region are associated with Behcet's disease in a Northern Chinese Han population
IL12RB2 polymorphisms correlate with risk of lung adenocarcinoma.
The effects of rs3762315 and rs3762316 single nucleotide polymorphisms in 5' flanking region on IL12RB2 transcription
Estrogen receptor beta 2 (Montrer ESR2 Anticorps) regulates IL12RB2 expression via p38 MAPK (Montrer MAPK14 Anticorps) signaling and inhibits non-small-cell lung cancer proliferation and invasion.

Cow (Bovine) Interleukin 12 Receptor, beta 2 (IL12RB2) interaction partners

Four SNPs in IFNGR2 (Montrer IFNGR2 Anticorps), IL12RB1 (Montrer IL12RB1 Anticorps), IL12RB2, and IL23R (Montrer IL23R Anticorps) were found to be associated with the MAP infection status of the resource population.

IL12RB2 profil antigène

Antigen Summary

The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene.

Alternative names and synonyms associated with IL12RB2

interleukin 12 receptor subunit beta 2 (IL12RB2) anticorps
interleukin 12 receptor, beta 2 (Il12rb2) anticorps
interleukin 12 receptor subunit beta 2 (Il12rb2) anticorps

A930027I18Rik anticorps
Ifnm anticorps
IL-12RB2 anticorps
IL12RB2 anticorps

Protein level used designations for IL12RB2

interleukin 12 receptor, beta 2 , interleukin 12 receptor beta-2 , interleukin-12 receptor subunit beta-2 , interleukin-12 receptor subunit beta-2-like , IL-12 receptor subunit beta-2 , IL-12R subunit beta-2 , IL-12R-beta-2 , interferon response to microorganisms , interleukin-12 receptor beta-2 chain , IL-12RB2 , interleukin-12 receptor beta 2 , IL-12 receptor beta-2

GENE ID	SPECIES
469348	Pan troglodytes
489550	Canis lupus familiaris
700677	Macaca mulatta
100393796	Callithrix jacchus
100456779	Pongo abelii
100582797	Nomascus leucogenys
16162	Mus musculus
171334	Rattus norvegicus
3595	Homo sapiens
424705	Gallus gallus
397178	Sus scrofa
282452	Bos taurus

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