Profil protéine

The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).

Alternative names and synonyms associated with Leptin Receptor (LEPR)

• leptin receptor (LEPR) anticorps
• leptin receptor (lepr) anticorps
• leptin receptor (Lepr) anticorps
• leptin receptor S homeolog (lepr.S) anticorps

• cd295 anticorps
• db anticorps
• diabetes anticorps
• Fa anticorps
• LEP-R anticorps
• Afficher tous les alias de synonymes
• lepr anticorps
• Leprb anticorps
• LEPRD anticorps
• LEPROT anticorps
• Modb1 anticorps
• Ob-R anticorps
• ob-rb anticorps
• OB-RGRP anticorps
• Ob-RM anticorps
• obese-like anticorps
• obl anticorps
• Obr anticorps
• ObRb anticorps

Protein level used designations for Leptin Receptor Protéines (LEPR)

OB receptor , huB219 , LEP-R , Leptin receptor (fatty) , OB-R , B219 , leptin receptor gene-related protein , cytokine receptor , leptin receptor long insert isoform , leptin receptor