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MPL Protéines

13 Résultats:

Myeloproliferative Leukemia Virus Oncogene (MPL) (AA 26-625) protein (rho-1D4 tag) Protein

Crystallography grade MPL Origine: Souris Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
N° du produit ABIN3121513
$5,919.98
Plus frais de port $45.00 et $24.00 pour carboglace
0.25 mg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 50 à 55 jours ouvrables

Myeloproliferative Leukemia Virus Oncogene (MPL) (AA 514-635) protein (His tag) Protein

Crystallography grade MPL Origine: Humain Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
N° du produit ABIN3074647
$7,594.15
Plus frais de port $45.00 et $24.00 pour carboglace
1 mg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 50 jours ouvrables

Myeloproliferative Leukemia Virus Oncogene (MPL) (AA 505-625) protein (His tag) Protein

Crystallography grade MPL Origine: Souris Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
N° du produit ABIN3121514
$7,594.15
Plus frais de port $45.00 et $24.00 pour carboglace
1 mg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 50 jours ouvrables

Myeloproliferative Leukemia Virus Oncogene (MPL) (AA 26-635) protein (rho-1D4 tag) Protein

Crystallography grade MPL Origine: Humain Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
N° du produit ABIN3074645
$8,431.43
Plus frais de port $45.00 et $24.00 pour carboglace
0.5 mg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 50 à 55 jours ouvrables

Myeloproliferative Leukemia Virus Oncogene (MPL) (AA 26-491) protein (His tag) Protein

Crystallography grade MPL Origine: Humain Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
N° du produit ABIN3074646
$10,832.86
Plus frais de port $45.00 et $24.00 pour carboglace
1 mg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 60 jours ouvrables

Myeloproliferative Leukemia Virus Oncogene (MPL) (AA 26-482) protein (His tag) Protein

Crystallography grade MPL Origine: Souris Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
N° du produit ABIN3121512
$10,832.86
Plus frais de port $45.00 et $24.00 pour carboglace
1 mg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 60 jours ouvrables

Myeloproliferative Leukemia Virus Oncogene (MPL) (AA 311-460) protein (His tag,T7 tag) Protein

MPL Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % IP, SDS, ELISA, WB
N° du produit ABIN1879570
$478.00
Plus shipping costs $45.00
50 μg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 10 à 13 jours ouvrables

Myeloproliferative Leukemia Virus Oncogene (MPL) (AA 66-260) protein (His tag,T7 tag) Protein

MPL Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % IP, SDS, ELISA, WB
N° du produit ABIN1879576
$498.00
Plus shipping costs $45.00
50 μg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 10 à 13 jours ouvrables

Myeloproliferative Leukemia Virus Oncogene (MPL) (AA 1-635) protein (GST tag) Protein

MPL Origine: Humain Hôte: Wheat germ Recombinant AP, AA, ELISA, WB
N° du produit ABIN1311206
$500.00
Plus frais de port $45.00 et $24.00 pour carboglace
10 μg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 11 à 12 jours ouvrables

Myeloproliferative Leukemia Virus Oncogene (MPL) (AA 26-491), (Extracellular) protein (His tag) Protein

MPL Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5709953
$501.60
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 11 jours ouvrables
  • Type Protein
    • Protein
  • Target Myeloproliferative Leukemia Virus Oncogene (MPL)
    • Myeloproliferative Leukemia Virus Oncogene (MPL)
    • Hemagglutinin (HA)
    • Hemoglobin beta (HBB)
    • Ribosome Binding Factor A (RBFA)
    • Triosephosphate Isomerase 1 (TPI1)
    • S-Adenosyl-Methionine Synthase (METK)
    • Hemoglobin, alpha 1 (HBA1)
    • Myoglobin (MB)
    • Tumor Necrosis Factor alpha (TNF alpha)
    • Thymidylate Kinase (Tmk)
    • Lipoyl synthase lipA
    • Growth Hormone 1 (GH1)
    • Interferon gamma (IFNG)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Uracil-DNA Glycosylase (UNG)
    • Malate Dehydrogenase (MDH)
    • Phosphoglucosamine Mutase (GLMM)
    • SARS-CoV-2 Spike
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • phosphatidylserine Decarboxylase (PISD)
    • Cysteinyl-tRNA Synthetase 2, Mitochondrial (Putative) (CARS2)
    • tRNA Methyltransferase 5 Homolog (S. Cerevisiae) (TRMT5)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • Interleukin 6 (IL6)
    • Interleukin 2 (IL2)
    • Cytochrome C, Somatic (CYCS)
    • Interleukin 4 (IL4)
    • CD40 Ligand (CD40LG)
    • Gp120
    • Porphobilinogen Deaminase (HEMC)
    • Plasminogen Activator Inhibitor 1 (SERPINE1)
    • Superoxide Dismutase 1, Soluble (SOD1)
    • Epidermal Growth Factor Receptor (EGFR)
    • 1-(5-Phosphoribosyl)-5-[(5-Phosphoribosylamino)methylideneamino] Imidazole-4-Carboxamide Isomerase (APG10)
    • Interleukin 10 (IL10)
    • Interleukin 8 (IL8)
    • Interleukin 1, beta (IL1B)
    • Prolactin (PRL)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Adenosylhomocysteinase (AHCY)
    • Ferrochelatase, HEMH (HEMH)
    • Thymidylate Synthase (THYA)
    • SARS-CoV-2 Spike S1
    • Uracil Phosphoribosyltransferase (UPP)
    • beta-2-Microglobulin (B2M)
    • Thymidine Kinase 1, Soluble (TK1)
    • Programmed Cell Death 1 (PDCD1)
    • Ribonuclease, RNase A Family, 1 (Pancreatic) (RNASE1)
    • Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
  • Application
    • SDS-PAGE (SDS)
    • ELISA
    • Western Blotting (WB)
    • Crystallization (Crys)
    • Affinity Purification (AP)
    • Immunoprecipitation (IP)
    • Antibody Array (AA)
    • Functional Studies (Func)
    • Screening Assay (ScA)
  • Réactivité
    • Humain
    • Souris
    • Rat
  • Images disponible
  • Hote
    • Cellules d'insectes
    • Escherichia coli (E. coli)
    • Wheat germ
    • Baculovirus infected Insect Cells
    • Levure
  • Epitope
    • AA 26-491
    • Extracellular
    • AA 1-500
    • AA 1-635
    • AA 26-482
    • AA 26-625
    • AA 26-635
    • AA 311-460
    • AA 505-625
    • AA 514-635
    • AA 66-260
    • Mature
  • Conjugué
    • Inconjugué
    • His tag
    • His tag,T7 tag
    • rho-1D4 tag
    • GST tag
  • Type Proteine
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • Crystallography grade

Profil protéine MPL

Profil protéine

In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the human homologue, named, c-mpl, was cloned. Sequence data revealed that c-mpl encoded a protein that was homologous with members of the hematopoietic receptor superfamily. Presence of anti-sense oligodeoxynucleotides of c-mpl inhibited megakaryocyte colony formation. The ligand for c-mpl, thrombopoietin, was cloned in 1994. Thrombopoietin was shown to be the major regulator of megakaryocytopoiesis and platelet formation. The protein encoded by the c-mpl gene, CD110, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs . TPO-R deficient mice were severely thrombocytopenic, emphasizing the important role of CD110 and thrombopoietin in megakaryocyte and platelet formation. Upon binding of thrombopoietin CD110 is dimerized and the JAK family of non-receptor tyrosine kinases, as well as the STAT family, the MAPK family, the adaptor protein Shc and the receptors themselves become tyrosine phosphorylated.

Alternative names and synonyms associated with MPL

  • MPL proto-oncogene, thrombopoietin receptor (MPL) anticorps
  • myeloproliferative leukemia virus oncogene (Mpl) anticorps
  • MPL proto-oncogene, thrombopoietin receptor (Mpl) anticorps
  • MPL proto-oncogene, thrombopoietin receptor (mpl) anticorps
  • c-mpl anticorps
  • c-mpl-I anticorps
  • c-mpl-II anticorps
  • CD110 anticorps
  • hlb219 anticorps
  • MPL anticorps
  • mpll anticorps
  • MPLV anticorps
  • THCYT2 anticorps
  • TPO-R anticorps
  • tpor anticorps
  • tpor.b anticorps

Protein level used designations for MPL

TPO-R , myeloproliferative leukemia protein , proto-oncogene c-Mpl , thrombopoietin receptor , myeloproliferative leukemia virus oncogene , thrombopoietin receptor-like , cytokine receptor , myeloproliferative leukemia virus oncogene, like , thrombopoietin receptor c-mpl

GENE ID SPECIES
4352 Homo sapiens
17480 Mus musculus
366455 Rattus norvegicus
414804 Gallus gallus
528492 Bos taurus
723813 Macaca mulatta
747522 Pan troglodytes
100066544 Equus caballus
100230798 Taeniopygia guttata
100355135 Oryctolagus cuniculus
100448006 Pongo abelii
100626347 Sus scrofa
445381 Danio rerio

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