Profil protéine

This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with SOCS2

• suppressor of cytokine signaling 2 (SOCS2) anticorps
• suppressor of cytokine signaling 2 (socs2) anticorps
• suppressor of cytokine signaling 2 (Socs2) anticorps

• 8030460M17 anticorps
• AI527257 anticorps
• AW108012 anticorps
• CIS2 anticorps
• Cish2 anticorps
• Afficher tous les alias de synonymes
• D130043N08Rik anticorps
• hg anticorps
• JAB anticorps
• si:dkey-202b22.1 anticorps
• Socs-2 anticorps
• socs2 anticorps
• SSI-2 anticorps
• SSI2 anticorps
• STATI2 anticorps

Protein level used designations for SOCS2

suppressor of cytokine signaling-2 , suppressor of cytokine signaling 2 , suppressor of cytokine signaling 2 variant 1 , CIS-2 , STAT induced STAT inhibitor-2 , STAT-induced STAT inhibitor 2 , STAT-induced STAT inhibitor-2 , cytokine-inducible SH2 protein 2 , cytokine inducible SH2-containing protein 2 , SOCS-2 , suppressor of cytokine signalling 2