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anti-Mouse (Murine) DPPA2 Anticorps:
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Dppa2/4 Facilitate Epigenetic Remodeling during Reprogramming to Pluripotency
Dppa2 and Dppa4 directly regulate the 2C-like cell population and associated transcripts, including Dux and the Zscan4 cluster.
a novel long non-coding RNA was found to silence its neighboring gene, Dppa2, in cis through recruiting Dnmt1, Dnmt3a and Dnmt3b
Results identified a new family of pluripotency-related oncogenes consisting of DPPA2 and DPPA4.
has important roles in lung development, where it is no longer expressed, by leaving epigenetic marks from earlier developmental stages
Results showed that the expression of Dppa2 decreased markedly in differentiated cells. Dppa2 might play a role in maintenance of the undifferentiated state and proliferation of ES cells
Study of expression and function of pluripotent markers such as Dppa2 and Dppa4 is likely to unveil new aspects of the regulation of pluripotency and germ line development in mammals.
High DPPA2 Protein Expression is Associated with Gastric Cancer Metastasis
results showed that DPPA2 expression was significantly correlated to the depth of tumor invasion and progression of tumor cells through advanced stages in colorectal cancer.
A important role of HIWI and DPPA2 in tumorigenesis and also in lymph node metastasis of tumor cells.
Differential expression of the embryo/cancer gene ECSA(DPPA2) in human preimplantation development.
ECSA/DPPA2 is a promising target for antigen-specific immunotherapy in non-small cell lung cancers
In normal tissues, PLAC1 expression was restricted to the placenta while DPPA2 expression was restricted to the placenta and testis.
Binds to target gene promoters, including NKX2-5 and SYCE1, but not GATA4, and may be involved in the maintenance of the active epigenetic status of these genes (By similarity).
developmental pluripotency-associated 2
, developmental pluripotency-associated protein 2
, embryonic stem cell-associated transcript 15-2 protein
, pluripotent embryonic stem cell-related gene 1 protein
, cancer/testis antigen 100
, embryonic stem cell (ESC) associated transcript 15-2
, developmental pluripotency associated 2
, protein DppA2