Hydroxysteroid (11-Beta) Dehydrogenase 2 Protéines
11 Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) Protéines de 6 fabricants sont disponibles sur www.anticorps-enligne.fr.
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Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 1-405) protein (His tag) Protein
Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 1-386) protein (His tag) Protein
Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 1-405) protein (GST tag) Protein
Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 71-170) protein (GST tag) Protein
Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 58-393) protein (His tag) Protein
Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) protein (Myc-DYKDDDDK Tag) Protein
Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) Protéine Protein
Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 1-400) protein (His tag) Protein
Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 1-404) protein (His tag) Protein
Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 1-406) protein (His tag) Protein
Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 1-427) protein (His tag) Protein
Profil protéine Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2)
Profil protéine
There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor. In tissues that do not express the mineralocorticoid receptor, such as the placenta and testis, it protects cells from the growth-inhibiting and/or pro-apoptotic effects of cortisol, particularly during embryonic development. Mutations in this gene cause the syndrome of apparent mineralocorticoid excess and hypertension.
Alternative names and synonyms associated with Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2)
- hydroxysteroid (11-beta) dehydrogenase 2 L homeolog (hsd11b2.L) anticorps
- hydroxysteroid 11-beta dehydrogenase 2 (HSD11B2) anticorps
- hydroxysteroid 11-beta dehydrogenase 2 (Hsd11b2) anticorps
- 11-HSD2 anticorps
- 11HSD2 anticorps
- AME anticorps
- AME1 anticorps
- HSD2 anticorps
- HSD11B2 anticorps
- HSD11K anticorps
- MGC81883 anticorps
- SDR9C3 anticorps
Protein level used designations for HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2 , corticosteroid 11-beta-dehydrogenase isozyme 2 , 11 beta-hydroxysteroid dehydrogenase type 2 , -HSD11 type II , 11-DH2 , 11-beta-HSD2 , 11-beta-hydroxysteroid dehydrogenase type 2 , 11-beta-hydroxysteroid dehydrogenase type II , NAD-dependent 11-beta-hydroxysteroid dehydrogenase , short chain dehydrogenase/reductase family 9C member 3 , 11-beta hydroxysteroid dehydrogenase , hydroxysteroid 11-beta dehydrogenase 2 , 11-beta-hydroxysteroid dehydrogenase 2 , 11(beta)-HSD2 , Hydroxysteroid dehydrogenase, 11 beta type 2
GENE ID | SPECIES |
---|---|
444491 | Xenopus laevis |
100034124 | Equus caballus |
100529249 | Felis catus |
3291 | Homo sapiens |
396948 | Sus scrofa |
282434 | Bos taurus |
100009531 | Oryctolagus cuniculus |
489758 | Canis lupus familiaris |
15484 | Mus musculus |
25117 | Rattus norvegicus |
443530 | Ovis aries |
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