anti-Humain C1S anticorps pour Immunoassay

Recommended C1S Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Complement Component 1, S Subcomponent (C1S) Anticorps
  • AA959438
  • AI255193
  • AI327365
  • C1sa
  • r-gsp
  • C1S
  • complement C1s
  • complement component 1, s subcomponent 1
  • complement component 1, s subcomponent
  • complement component 1, s subcomponent L homeolog
  • complement C1s subcomponent
  • C1S
  • C1s1
  • C1s
  • c1s
  • c1s.L
  • LOC100558615
Reactivité
Humain
115
25
24
4
1
Hôte
Souris
64
48
4
Clonalité
Monoclonal
Conjugué
Cet anticorp C1S est non-conjugé
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunoassay (IA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Inhibition Assay (InhA), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
69
46
36
15
14
13
12
6
5
3
3
3
2
1
1
1
1
1
1
Options
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N° du produit ABIN2191986
$ 647.55
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
-12.779206 ABIN4299880 BP FACS IA IHC IHC (fro) IHC (p) Neut WB Mouse IgG2a Connectez-vous pour afficher M241 0

General

Antigène Complement Component 1, S Subcomponent (C1S) Anticorps
Reactivité Humain
(115), (25), (24), (4), (1)
Hôte Souris
(64), (48), (4)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp C1S est non-conjugé
(3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunoassay (IA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Inhibition Assay (InhA), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(69), (46), (36), (15), (14), (13), (12), (6), (5), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Pubmed 1 référence disponible
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Détail du produit anti-C1S anticorps

Détail du antigène C1S Information d'application Stockage References for anti-C1S antibody (ABIN2191986) Images
Stérilité 0.2 μm filtered
Clone M81
Plasmids, Primers & others

Détail du antigène C1S

Détail du produit anti-C1S anticorps Information d'application Stockage References for anti-C1S antibody (ABIN2191986) Images Haut de la page
Antigène
Autre désignation c1s (C1S Antibody Extrait)
Sujet Monoclonal antibody M81 reacts with an epitope on human C protein activated C1s, a subcomponent of the first component of C (C1). Activated C1s is a glycosylated single-polypeptide zymogen, MW 85 kD. Activation of the proenzyme C1s occurs through cleavage by the active form of C1r. The activated protease, activated C1s, consists of a disulfide-linked H chain and a L chain. Activated C1s is a serine protease and its catalytic site is located in the L chain. Activation of the classical C pathway is triggered by activated C1s which cleaves C4 and C2 to form the C3 convertase, C4bC2a. The epitope recognised by the antibody M81 is domain IV and/or V of the gamma-domain of activated C1s. Monoclonal antibody M81 blocks C4 activation and C4 binding to activated C1s. The antibody reacts around the binding site of C1s and reacts with both active and inactive C1s.
Pathways Système du Complément

Information d'application

Détail du produit anti-C1S anticorps Détail du antigène C1S Stockage References for anti-C1S antibody (ABIN2191986) Images Haut de la page
Indications d'application For immunohistology, flow cytometry and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. For inhibition of C4 activation by C1s dilutions have to be made according to the amounts C1s to be inactivated.
Restrictions For Research Use only

Stockage

Détail du produit anti-C1S anticorps Détail du antigène C1S Information d'application References for anti-C1S antibody (ABIN2191986) Images Haut de la page
Buffer PBS containing 0.1 % bovine serum albumin.
Stock 4 °C
Stockage commentaire Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
Date de péremption 12 months

References for anti-C1S antibody (ABIN2191986)

Détail du produit anti-C1S anticorps Détail du antigène C1S Information d'application Stockage Images Haut de la page
Produit citée dans:

Matsumoto, Nagaki, Kitamura, Kuramitsu, Nagasawa, Seya: "Probing the C4-binding site on C1s with monoclonal antibodies. Evidence for a C4/C4b-binding site on the gamma-domain." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 142, Issue 8, pp. 2743-50, 1989