anti-Humain C4A anticorps pour Immunofluorescence

Recommended C4A Antibody

Antigène
Complement Fragment C4a (C4a) Anticorps
  • C4
  • C4A2
  • C4A3
  • C4A4
  • C4A6
  • C4AD
  • C4S
  • CO4
  • CPAMD2
  • RG
  • Slp
  • C4-1
  • C4b
  • complement C4A (Rodgers blood group)
  • complement component 4A (Rodgers blood group)
  • C4A
  • C4a
Reactivité
Humain
29
6
4
1
Hôte
Souris
21
11
1
1
Clonalité
Monoclonal
Conjugué
Cet anticorp C4A est non-conjugé
2
2
1
Application
ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
19
15
14
8
7
5
3
2
2
1
Options
N° du produit ABIN6296522
$ 575.30
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
1 ABIN5573384 IF Mouse IgG1 TDM16 0
1 ABIN5573383 IF Mouse IgG1 C4D205 0
1 ABIN6296400 ELISA IF Mouse 0
1 ABIN6297138 ELISA IF IHC Mouse 0
1 ABIN6297151 ELISA IF Mouse 0
1 ABIN6296523 IF IHC Mouse 0
1 ABIN6297152 ELISA IF Mouse 0

General

Antigène Complement Fragment C4a (C4a) Anticorps
Reactivité Humain
(29), (6), (4), (1)
Hôte Souris
(21), (11), (1), (1)
Clonalité
Monoclonal
Conjugué Cet anticorp C4A est non-conjugé
(2), (2), (1)
Application ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
(19), (15), (14), (8), (7), (5), (3), (2), (2), (1)
Fournisseur

Détail du produit anti-C4A anticorps

Détail du antigène C4A Information d'application Stockage Images
Fonction Mouse anti-Human C4d Antibody Complement 4d [Sodium Azide Free]
Specificité Intracytoplasmic vacuoles of endothelial cells, Secreted
Purification Human protein was used as the immunogen for this C4d antibody.
Immunogène Human protein was used as the immunogen for this C4d antibody.
Plasmids, Primers & others

Détail du antigène C4A

Détail du produit anti-C4A anticorps Information d'application Stockage Images Haut de la page
Antigène
Autre désignation Complement C4-A (C4a Antibody Extrait)
Sujet

Target Description: This antibody is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound protein. C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of antibodies to specific target molecules. Following activation and degradation of the C4 Molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product C4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries is a key indicator for acute humoral (i.e. antibody-mediated) rejection of kidney, heart, pancreas and lung allografts. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. C4d has been shown to be a significant predictor of transplant kidney graft survival. C4d antibody, combined with antibody to C3d, can be utilized as a tool for diagnosis of allograft rejection that may warrant a prompt and aggressive anti-rejection treatment.

Gene Symbol: C4A///CO4///CPAMD2///C4B///CO4///CPAMD3///C4B_2

ID gène 720
UniProt P0C0L4, P0C0L5
Pathways Système du Complément

Information d'application

Détail du produit anti-C4A anticorps Détail du antigène C4A Stockage Images Haut de la page
Indications d'application IF: 1:50-1:100
IHC (FFPE): 1:200-1:400 for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2),ELISA: 1-2 μg/mL, order the BSA-free format
Restrictions For Research Use only

Stockage

Détail du produit anti-C4A anticorps Détail du antigène C4A Information d'application Images Haut de la page
Buffer In 1X PBS ( pH 7.4), BSA free, sodium azide free
Agent conservateur Azide free
Stock 4 °C
Stockage commentaire 2-8°C