anti-Humain C4A anticorps pour Immunofluorescence

Recommended C4A Antibody

Antigène
Complement Fragment C4a (C4a) Anticorps
  • C4
  • C4A2
  • C4A3
  • C4A4
  • C4A6
  • C4AD
  • C4S
  • CO4
  • CPAMD2
  • RG
  • Slp
  • C4-1
  • C4b
  • complement C4A (Rodgers blood group)
  • complement component 4A (Rodgers blood group)
  • C4A
  • C4a
Reactivité
Humain
32
6
4
1
Hôte
Souris
21
14
1
1
Clonalité
Monoclonal
Conjugué
Cet anticorp C4A est conjugé à/à la CF
2
2
1
Application
Coating (Coat), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Staining Methods (StM)
19
18
17
8
8
5
3
2
2
2
2
1
Options
N° du produit ABIN6935975
$ 522.06
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
1 ABIN6296522 ELISA IF IHC Mouse 0
1 ABIN5573384 IF Mouse IgG1 TDM16 0
1 ABIN5573383 IF Mouse IgG1 C4D205 0
1 ABIN6296400 ELISA IF Mouse 0
1 ABIN6297138 ELISA IF IHC Mouse 0
1 ABIN6297151 ELISA IF Mouse 0
1 ABIN6296523 IF IHC Mouse 0
1 ABIN6297152 ELISA IF Mouse 0

General

Antigène Complement Fragment C4a (C4a) Anticorps
Reactivité Humain
(32), (6), (4), (1)
Hôte Souris
(21), (14), (1), (1)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp C4A est conjugé à/à la CF
(2), (2), (1)
Application Coating (Coat), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Staining Methods (StM)
(19), (18), (17), (8), (8), (5), (3), (2), (2), (2), (2), (1)
Fournisseur

Détail du produit anti-C4A anticorps

Détail du antigène C4A Information d'application Stockage Images
Specificité This MAb is specific to Complement 4d (C4d) and reacts with the secreted as well as cell-bound C4d.C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of Abs to specific target molecules. Following activation and degradation of the C4 Molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product Complement 4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries is a key indicator for acute humoral (i.e. antibody-mediated) rejection of kidney, heart, pancreas and lung allografts. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. It has been shown to be a significant predictor of transplant kidney graft survival. Anti-C4d, combined with anti-C3d, can be utilized as a tool for diagnosis of allograft rejection that may warrant a prompt and aggressive anti-rejection treatment.
Purification Purified by Protein A/G
Immunogène Recombinant human Complement 4d protein
Clone C4D204
Isotype IgG1, kappa
Plasmids, Primers & others

Détail du antigène C4A

Détail du produit anti-C4A anticorps Information d'application Stockage Images Haut de la page
Antigène
Autre désignation C4A (C4a Antibody Extrait)
Poids moléculaire 192kDa (predicted)
ID gène 720, 721
Pathways Système du Complément

Information d'application

Détail du produit anti-C4A anticorps Détail du antigène C4A Stockage Images Haut de la page
Indications d'application

Positive Control: Rejected Renal Transplant Tissue.

Known Application: ELISA (For coating use Ab at 1-2 μg/mL order Ab without BSA), Immunofluorescence (1:50-1:100),Immunohistochemistry (Formalin-fixed) (1:200-1:400 for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA, pH 7.5-8.5, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions For Research Use only

Stockage

Détail du produit anti-C4A anticorps Détail du antigène C4A Information d'application Images Haut de la page
Concentration 100 μg/mL
Buffer 10 mM PBS with 0.05 % BSA & 0.05 % azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Date de péremption 24 months