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anti-Human C7 Anticorps:
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Human Monoclonal C7 Primary Antibody pour Func, ELISA - ABIN2477818
Makheja: Atherosclerosis: the eicosanoid connection. dans Molecular and cellular biochemistry 1992
Show all 3 Pubmed References
Human Polyclonal C7 Primary Antibody pour IHC, IHC (p) - ABIN4299873
Kato, Nicholson, Neiman, Rantalainen, Holmes, Barrett, Uhlén, Nilsson, Spector, Schwenk: Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model. dans Proteome science 2011
this study shows that GG genotype of C7 provides protection against fibrosis severity while showing a higher risk for hepatocellular carcinoma in patients with hepatitis C
Two case reports of C7 deficiency leading to recurrent meningitis and other bacterial infections are described.
The complement C7 rs6876739 CC genotypes and mannan-binding lectin (MBL2) gene polymorphisms of liver donors were significantly associated with bacterial infection in recipients.
Complement proteins C7 and CFH control the stemness of liver cancer cells via LSF-1 pathway.
Complement C5b-9 complex sensitizes 661W photoreceptor cells to both apoptosis and necroptosis.
Borrelial CspA binds the human terminal complement components C7 and C9 and blocks assembly and membrane insertion of the terminal complement complex (TCC).
These overall results suggest a lack of strong association with the C2 and C7 gene polymorphisms to the susceptibility of systemic lupus erythematosus in the Malaysian population.
Studies indicate that the deletion defect may be a more commonly distributed cause of C7 deficiency in Ireland.
Complement C5b-9 induce a JNK/Bid-dependent and JNK-independent necrotic cell death.
C7 isoelectric focusing variants can determine meningococcal killing in the early stage of infection when antibody-independent killing prevails.
To determine transcriptional regulation of the human complement component C7, a 1 kb promoter fragment was cloned and the transcription start site was determined. C7 is expressed by the hepatoma-derived cell line Hep-3B, but not by Hep-G2.
A model is suggested for an irreversible membrane attack complex assembly in which the complement 7 factor I modules, but not those in complement 6, are bound to the C345C (netrin receptor) domain of complement 5 within the fully assembled complex.
The interaction between the factor I domain of C7 and the C345C domain at the C terminus of the C5 alpha-chain plays an essential role in complement membrane attack complex formation and complement lytic activity.
recurrence of fulminant meningococcal disease in a complement component C7-deficient patient
Cell cycle induction by C5b-9 in aortic endothelial cells is RGC-32 dependent and this is in part through regulation of Akt and growth factor release.
membrane associated C7 acts as a trap for the late complement components to control excessive inflammation induced by SC5b-9
C7 is associated with multiple sclerosis pathogenesis.
Data show that the two C7-FIMs pack closely together with an approximate 2-fold rotational symmetry that is rarely seen in module pairs and has not been observed in FD-containing proteins.
data indicate a role for complement C7 in the development of lung histopathology in Mycobacterium tuberculosis infection, with a potential role for dysregulation in innate interaction with lymphocytes and their subsequent production of cytokines
C7 is a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection.
complement component C7
, complement C7
, complement component 7
, complement component C7-like