anti-Humain Complement Factor H anticorps pour Enzyme Immunoassay

Recommended Complement Factor H Antibody

Antigène
Complement Factor H (CFH) Anticorps
  • AHUS1
  • AMBP1
  • ARMD4
  • ARMS1
  • CFHL3
  • FH
  • FHL1
  • HF
  • HF1
  • HF2
  • HUS
  • Mud-1
  • NOM
  • Sas-1
  • Sas1
  • Fh
  • CFH
  • im:7147412
  • si:ch211-207o17.2
  • fH
  • armd4
  • arms1
  • cfh
  • cfhl3
  • fhl1
  • hf1
  • hf2
  • hus
  • complement factor H
  • complement component factor h
  • complement factor H-related protein 5
  • complement factor H L homeolog
  • CFH
  • Cfh
  • cfh
  • LOC100399888
  • LOC100733902
  • cfh.L
Épitope
AA 751-780, Middle Region
24
17
16
15
10
8
4
3
2
2
2
2
2
1
1
1
1
1
Reactivité
Humain
234
37
36
3
3
3
3
2
2
Hôte
Lapin
126
87
32
16
1
1
Clonalité
Polyclonal
Conjugué
Cet anticorp Complement Factor H est non-conjugé
22
14
5
4
4
4
4
4
4
4
4
3
2
2
2
2
2
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
172
120
77
42
32
26
24
22
15
10
10
9
8
5
4
1
1
1
1
Options

Images

N° du produit ABIN951646
$ 484.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
7 ABIN372860 EIA IHC (p) WB Goat IgG Internal Region Polyclonal 0
7 ABIN492561 EIA IHC (p) IP WB Mouse IgG1 OX-24 0
4 ABIN492503 EIA FACS IHC (p) IP WB Mouse IgG1 OX-24 0
1 ABIN181114 EIA FACS IHC (fro) WB Mouse IgG1 10-10-14 2
1 ABIN1803647 EIA RIA Biotin Rabbit IgG Polyclonal 0
1 ABIN1803646 EIA RIA Rabbit IgG Polyclonal 0

General

Antigène Complement Factor H (CFH) Anticorps
Épitope AA 751-780, Middle Region
(24), (17), (16), (15), (10), (8), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivité Humain
(234), (37), (36), (3), (3), (3), (3), (2), (2)
Hôte Lapin
(126), (87), (32), (16), (1), (1)
Clonalité
Polyclonal
Conjugué Cet anticorp Complement Factor H est non-conjugé
(22), (14), (5), (4), (4), (4), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(172), (120), (77), (42), (32), (26), (24), (22), (15), (10), (10), (9), (8), (5), (4), (1), (1), (1), (1)
Pubmed 3 références disponible
Fournisseur

Détail du produit anti-Complement Factor H anticorps

Détail du antigène Complement Factor H Information d'application Stockage References for anti-Complement Factor H antibody (ABIN951646) Images
Specificité This antibody reacts to CFH.
Réactivité croisée (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Immunogène KLH conjugated synthetic peptide between 751-780 amino acids from the Central region of human CFH
Isotype Ig Fraction
Plasmids, Primers & others

Détail du antigène Complement Factor H

Détail du produit anti-Complement Factor H anticorps Information d'application Stockage References for anti-Complement Factor H antibody (ABIN951646) Images Haut de la page
Antigène
Sujet This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: CFH, H factor 1, HF, HF1, HF2
Poids moléculaire 139096 Da
ID gène 3075
NCBI Accession NP_000177
Pathways Système du Complément, Cellular Response to Molecule of Bacterial Origin

Information d'application

Détail du produit anti-Complement Factor H anticorps Détail du antigène Complement Factor H Stockage References for anti-Complement Factor H antibody (ABIN951646) Images Haut de la page
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Stockage

Détail du produit anti-Complement Factor H anticorps Détail du antigène Complement Factor H Information d'application References for anti-Complement Factor H antibody (ABIN951646) Images Haut de la page
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Complement Factor H antibody (ABIN951646)

Détail du produit anti-Complement Factor H anticorps Détail du antigène Complement Factor H Information d'application Stockage Images Haut de la page
Background publications

Dieterich, Hammerschmidt, Richter, Skerka, Wallich, Matuschka, Zipfel, Kraiczy: "Inadequate binding of immune regulator factor H is associated with sensitivity of Borrelia lusitaniae to human complement." dans: Infection and immunity, Vol. 78, Issue 11, pp. 4467-76, 2010

Sofat, Casas, Kumari, Talmud, Ireland, Kivimaki, Marmot, Hughes, Thom, Ebrahim, Whittaker, Smeeth, Lawlor, Humphries, Hingorani: "Genetic variation in complement factor H and risk of coronary heart disease: eight new studies and a meta-analysis of around 48,000 individuals." dans: Atherosclerosis, Vol. 213, Issue 1, pp. 184-90, 2010

Davila, Wright, Khor, Sim, Binder, Breunis, Inwald, Nadel, Betts, Carrol, de Groot, Hermans, Hazelzet, Emonts, Lim, Kuijpers, Martinon-Torres, Salas, Zenz, Levin, Hibberd: "Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease." dans: Nature genetics, Vol. 42, Issue 9, pp. 772-6, 2010

Images

Détail du produit anti-Complement Factor H anticorps Détail du antigène Complement Factor H Information d'application Stockage References for anti-Complement Factor H antibody (ABIN951646) Haut de la page
Images (Fournisseur)
Immunofluorescence (IF) image for anti-Complement Factor H (CFH) (AA 751-780), (Middle Region) antibody (ABIN951646) Confocal immunofluorescent analysis of CFH Antibody (Center) with A549 cell followed ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Complement Factor H (CFH) (AA 751-780), (Middle Region) antibody (ABIN951646) CFH antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin em...
Western Blotting (WB) image for anti-Complement Factor H (CFH) (AA 751-780), (Middle Region) antibody (ABIN951646) CFH Antibody (Center) western blot analysis in K562 cell line lysates (35µg/lane).Thi...