anti-Rat (Rattus) Complement Factor H anticorps pour Enzyme Immunoassay

Recommended Complement Factor H Antibody

Antigène
Complement Factor H (CFH) Anticorps
  • AHUS1
  • AMBP1
  • ARMD4
  • ARMS1
  • CFHL3
  • FH
  • FHL1
  • HF
  • HF1
  • HF2
  • HUS
  • Mud-1
  • NOM
  • Sas-1
  • Sas1
  • Fh
  • CFH
  • im:7147412
  • si:ch211-207o17.2
  • fH
  • armd4
  • arms1
  • cfh
  • cfhl3
  • fhl1
  • hf1
  • hf2
  • hus
  • complement factor H
  • complement component factor h
  • complement factor H-related protein 5
  • complement factor H L homeolog
  • CFH
  • Cfh
  • cfh
  • LOC100399888
  • LOC100733902
  • cfh.L
Reactivité
Souris, Rat (Rattus)
235
36
35
3
3
3
3
2
2
Hôte
Souris
127
86
32
16
1
1
Clonalité
Monoclonal
Conjugué
Cet anticorp Complement Factor H est non-conjugé
22
14
5
4
4
4
4
4
4
4
4
3
2
2
2
2
2
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
172
120
77
42
33
26
25
22
15
10
9
9
8
5
4
1
1
1
1
Options
N° du produit ABIN5540274
$ 705.12
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
1 ABIN5540273 EIA IHC (fro) WB FITC Mouse IgG1 1A2 0

General

Antigène Complement Factor H (CFH) Anticorps
Reactivité Souris, Rat (Rattus)
(235), (36), (35), (3), (3), (3), (3), (2), (2)
Hôte Souris
(127), (86), (32), (16), (1), (1)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp Complement Factor H est non-conjugé
(22), (14), (5), (4), (4), (4), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(172), (120), (77), (42), (33), (26), (25), (22), (15), (10), (9), (9), (8), (5), (4), (1), (1), (1), (1)
Fournisseur

Détail du produit anti-Complement Factor H anticorps

Détail du antigène Complement Factor H Information d'application Stockage Images
Specificité The monoclonal antibody 1A2 recognizes Mouse complement factor H (CFH).
Purification Purified
Immunogène Mouse factor H-human IgG fusion protein.
Clone 1A2
Isotype IgG1
Plasmids, Primers & others

Détail du antigène Complement Factor H

Détail du produit anti-Complement Factor H anticorps Information d'application Stockage Images Haut de la page
Antigène
Sujet CFH is the first regulatory protein of the alternative pathway of the complement system. There are three pathways of complement activation classical, alternative, and lectin activation pathway. These pathways converge to form C3/C5 convertases that generate C3a, C3b,C5a, and C5b, each with substantial biologic activity. Complement regulators are necessary to prevent the injudicious production of these mediators and potential injury to self-tissue. The plasma proteins CFH, C4-binding protein and the cell membrane proteins complement receptor 1 (CR1 CD35), decay-accelerating factor (CD55), and membrane co-factor protein (CD46) all are members of the regulators of complement activation family. These proteins have natural affinity for C3b and/or C4b, which confers on them the ability to accelerate the intrinsic decay of C3/C5 convertases and/or act as co-factor for the cleavage and inactivation (i) of C3b and C4b by complement factor I (CFI). Genetic human analyses reveals a clear association of CFH with different human diseases. These include diseases of the kidney, the atypical form of Hemolytic Uremic Syndrome (aHUS) and membranoproliferative glomerulonephritis (MPGN). Furthermore, CFH is associated with age-related macular degeneration (AMD), a disease of the eye.
UniProt P06909
Pathways Système du Complément, Cellular Response to Molecule of Bacterial Origin

Information d'application

Détail du produit anti-Complement Factor H anticorps Détail du antigène Complement Factor H Stockage Images Haut de la page
Indications d'application Immuno Assays. Western blot . Immunohistochemistry on Frozen Sections The typical starting working dilution is 1/50.
Restrictions For Research Use only

Stockage

Détail du produit anti-Complement Factor H anticorps Détail du antigène Complement Factor H Information d'application Images Haut de la page
Format Liquid
Buffer Buffer System: PBS Preservatives: 0.02 % Sodium Azide Stabilizers: 0.1 % BSA
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
Date de péremption 12 months