Profil protéine

This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.

Alternative names and synonyms associated with BCL10

• B-cell CLL/lymphoma 10 (BCL10) anticorps
• B-cell CLL/lymphoma 10 (Bcl10) anticorps
• B-cell CLL/lymphoma 10 (bcl10) anticorps
• B-cell lymphoma/leukemia 10-like (LOC100223183) anticorps
• B cell leukemia/lymphoma 10 (Bcl10) anticorps
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• B-cell lymphoma/leukemia 10 (bcl10) anticorps

• AI132454 anticorps
• BCL-10 anticorps
• bcl10 anticorps
• c-E10 anticorps
• C81403 anticorps
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• CARMEN anticorps
• cE10 anticorps
• CIPER anticorps
• CLAP anticorps
• ME10 anticorps

Protein level used designations for BCL10

B-cell lymphoma/leukemia 10 , CARD containing molecule enhancing NF-kB , CARD-containing apoptotic signaling protein , CARD-containing molecule enhancing NF-kappa-B , CARD-containing proapoptotic protein , CED-3/ICH-1 prodomain homologous E10-like regulator , cCARMEN , caspase-recruiting domain-containing protein , cellular homolog of vCARMEN , cellular-E10 , hCLAP , mammalian CARD-containing adapter molecule E10 , B-cell leukemia/lymphoma 10 , R-RCD1 , RCD , bcl-10 , B-cell lymophoma 10 protein , B-cell CLL/lymphoma 10 , B cell lymphoma/leukemia 10 , CARD-like apoptotic protein