anti-Humain CCR5 anticorps pour Intracellular Flow Cytometry

Recommended CCR5 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
C-C Chemokine Receptor Type 5 (CCR5) Anticorps
  • CC-CKR-5
  • CCCKR5
  • CCR-5
  • CD195
  • CKR-5
  • CKR5
  • CMKBR5
  • IDDM22
  • Ckr5
  • Cmkbr5
  • CCR1-L
  • GPCR
  • CCR5
  • AM4-7
  • CCR5-L
  • C-C motif chemokine receptor 5 (gene/pseudogene)
  • chemokine (C-C motif) receptor 5
  • C-C motif chemokine receptor 5
  • C-C motif chemokine receptor 2
  • CCR5
  • Ccr5
  • CCR2
Reactivité
Humain
472
79
64
14
14
3
2
1
1
1
1
1
Hôte
Souris
227
180
72
15
14
Clonalité
Monoclonal
Conjugué
Cet anticorp CCR5 est conjugé à/à la PE
42
27
20
19
19
16
14
13
9
9
9
6
5
5
5
5
4
4
4
4
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
302
208
139
65
64
57
56
33
29
18
14
12
8
7
6
5
4
4
3
2
2
2
2
2
1
1
1
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N° du produit ABIN2663124
Produit non disponible pour cette région.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN2661375 FACS ICFC FITC Mouse IgG2b kappa Connectez-vous pour afficher J418F1 1
1 ABIN2661552 ICFC FITC Rat IgG2a kappa Connectez-vous pour afficher HEK-1-85a 11
1 ABIN2663125 FACS ICFC PE Mouse IgG1 kappa Connectez-vous pour afficher T21-8 6
1 ABIN2661376 FACS ICFC FITC Mouse IgG2b kappa Connectez-vous pour afficher J418F1 1

General

Antigène C-C Chemokine Receptor Type 5 (CCR5) Anticorps
Reactivité Humain
(472), (79), (64), (14), (14), (3), (2), (1), (1), (1), (1), (1)
Hôte Souris
(227), (180), (72), (15), (14)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp CCR5 est conjugé à/à la PE
(42), (27), (20), (19), (19), (16), (14), (13), (9), (9), (9), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
(302), (208), (139), (65), (64), (57), (56), (33), (29), (18), (14), (12), (8), (7), (6), (5), (4), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1)
Pubmed 6 références disponible
Fournisseur Connectez-vous pour afficher

Détail du produit anti-CCR5 anticorps

Détail du antigène CCR5 Information d'application Stockage References for anti-CCR5 antibody (ABIN2663124) Images
Purification The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Clone T21-8
Isotype IgG1 kappa

Détail du antigène CCR5

Détail du produit anti-CCR5 anticorps Information d'application Stockage References for anti-CCR5 antibody (ABIN2663124) Images Haut de la page
Antigène
Autre désignation CD195 (CCR5 Antibody Extrait)
Sujet CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1α, MIP-1β, and RANTES and is expressed on a subset of T cells and monocytes. CD195 mediates an intracellular signal thought to induce differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry, modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. The T21/8 monoclonal antibody has high affinity to CCR5 N-terminal epitope (Met1-Lys22) and is useful for flow cytometric analysis, immunoprecipitation, immunofluorescence microscopy, and ELISA assay of CCR5 expression.
Pathways Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size

Information d'application

Détail du produit anti-CCR5 anticorps Détail du antigène CCR5 Stockage References for anti-CCR5 antibody (ABIN2663124) Images Haut de la page
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Stockage

Détail du produit anti-CCR5 anticorps Détail du antigène CCR5 Information d'application References for anti-CCR5 antibody (ABIN2663124) Images Haut de la page
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Protect from prolonged exposure to light. Do not freeze.
Stock 4 °C
Stockage commentaire The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-CCR5 antibody (ABIN2663124)

Détail du produit anti-CCR5 anticorps Détail du antigène CCR5 Information d'application Stockage Images Haut de la page
Background publications

Pollok-Kopp, Schwarze, Baradari, Oppermann: "Analysis of ligand-stimulated CC chemokine receptor 5 (CCR5) phosphorylation in intact cells using phosphosite-specific antibodies." dans: The Journal of biological chemistry, Vol. 278, Issue 4, pp. 2190-8, 2003

Huttenrauch, Nitzki, Lin, Höning, Oppermann: "Beta-arrestin binding to CC chemokine receptor 5 requires multiple C-terminal receptor phosphorylation sites and involves a conserved Asp-Arg-Tyr sequence motif." dans: The Journal of biological chemistry, Vol. 277, Issue 34, pp. 30769-77, 2002

Combadiere, Ahuja, Tiffany, Murphy: "Cloning and functional expression of CC CKR5, a human monocyte CC chemokine receptor selective for MIP-1(alpha), MIP-1(beta), and RANTES." dans: Journal of leukocyte biology, Vol. 60, Issue 1, pp. 147-52, 1996

Deng, Liu, Ellmeier, Choe, Unutmaz, Burkhart, Di Marzio, Marmon, Sutton, Hill, Davis, Peiper, Schall, Littman, Landau: "Identification of a major co-receptor for primary isolates of HIV-1." dans: Nature, Vol. 381, Issue 6584, pp. 661-6, 1996

Samson, Labbe, Mollereau, Vassart, Parmentier: "Molecular cloning and functional expression of a new human CC-chemokine receptor gene." dans: Biochemistry, Vol. 35, Issue 11, pp. 3362-7, 1996

Raport, Gosling, Schweickart, Gray, Charo: "Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1beta, and MIP-1alpha." dans: The Journal of biological chemistry, Vol. 271, Issue 29, pp. 17161-6, 1996

Images

Détail du produit anti-CCR5 anticorps Détail du antigène CCR5 Information d'application Stockage References for anti-CCR5 antibody (ABIN2663124) Haut de la page
Supplier Images
Flow Cytometry (FACS) image for anti-C-C Chemokine Receptor Type 5 (CCR5) antibody (PE) (ABIN2663124) anti-C-C Chemokine Receptor Type 5 (CCR5) antibody (PE)