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anti-Human CD247 Anticorps:
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Mouse (Murine) Monoclonal CD247 Primary Antibody pour CyTOF, FACS - ABIN4900709
Jones, Stumhofer, Foster, Twohig, Hertzog, Topley, Williams, Hunter, Jenkins, Wang, Jones: Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. dans FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011
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Mouse (Murine) Monoclonal CD247 Primary Antibody pour CyTOF, FACS - ABIN4900705
Vang, Housley, Dong, Basole, Ben-Sasson, Kream, Epstein, Clark, Brocke: Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac. dans The Biochemical journal 2013
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Human Monoclonal CD247 Primary Antibody pour ICC, FACS - ABIN1724734
Dumont, Blanchard, Di Bartolo, Lezot, Dufour, Jauliac, Hivroz: TCR/CD3 down-modulation and zeta degradation are regulated by ZAP-70. dans Journal of immunology (Baltimore, Md. : 1950) 2002
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Human Monoclonal CD247 Primary Antibody pour FACS, IF - ABIN965779
de Bakker, van Bodegom, van de Poll, Boelen, Nat, Rozema, Aerts: Is UV-B radiation affecting charophycean algae in shallow freshwater systems? dans The New phytologist 2005
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Mouse (Murine) Monoclonal CD247 Primary Antibody pour FACS - ABIN4898316
Lin, Xu, Jin, Zhong, Di, Lin: CXCL12 enhances exogenous CD4+CD25+ T cell migration and prevents embryo loss in non-obese diabetic mice. dans Fertility and sterility 2009
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Human Monoclonal CD247 Primary Antibody pour ICS - ABIN1177045
Alberola-Ila, Takaki, Kerner, Perlmutter: Differential signaling by lymphocyte antigen receptors. dans Annual review of immunology 1997
Mouse (Murine) Monoclonal CD247 Primary Antibody pour FACS - ABIN4898308
Lemay, Rintoul, Kus, Paterson, Garcia, Falls, Ferreira, Bridle, Conrad, Tang, Diallo, Arulanandam, Le Boeuf, Garson, Vanderhyden, Stojdl, Lichty, Atkins, Parato, Bell, Auer: Harnessing oncolytic virus-mediated antitumor immunity in an infected cell vaccine. dans Molecular therapy : the journal of the American Society of Gene Therapy 2012
Human Monoclonal CD247 Primary Antibody pour ICC, FACS - ABIN2749060
Dopfer, Schöpf, Louis-Dit-Sully, Dengler, Höhne, Klescová, Prouza, Suchanek, Reth, Schamel: Analysis of novel phospho-ITAM specific antibodies in a S2 reconstitution system for TCR-CD3 signalling. dans Immunology letters 2010
analysis of the assembly and surface expression of FcepsilonR1alpha in cells shows that CD16A associates equally well with human CD247 and FcepsilonR1gamma homodimers
Long-term lung function decline in asthma is associated with elevation of bronchial CD8 and CD4 at baseline, and CD8, CD3 and granzyme B at follow-up
Crk-dependent increased phosphorylation of CD3zeta coincided with inhibition of TCR downmodulation, supporting a positive role for Crk adaptor proteins in TCR-mediated signal amplification.
the immunohistochemical staining patterns of CD3 (Montrer CD3 Anticorps) and CD20 (Montrer MS4A1 Anticorps) in Malignant Lymphoma Cells, were investigated.
CD274 (Montrer CD274 Anticorps) up-regulation in new-onset type 1 diabetes mellitusis correlated with disease pathogenesis.
our observations suggested that CD247 gene polymorphism (rs858554) may associated with the susceptibility of RA.
CD3 (Montrer CD3 Anticorps)/28-activated T cells expanded in IL-7 (Montrer IL7 Anticorps) and IL-15 (Montrer IL15 Anticorps) produced greater expansion of memory stem T cells and central memory T cell-derived T cells compared with IL-2 (Montrer IL2 Anticorps). Our strategy provides a powerful tool to elucidate the characteristics of CAR-modified T cells, regardless of the protocol used for expansion, reveals the functional properties of each expanded T cell subset.
Multiple mutations were found in CD247 complementary DNAs (cDNAs) cloned from the patient as well as in cDNA and genomic DNA from other individuals, suggesting that genetic variation in this gene is frequent.
Single-nucleotide polymorphism in CD247 gene is associated with sclerotic graft-versus-host disease.
CD3Z hypermethylation was significantly correlated with SLE. CD3Z hypermethylation is an SLE risk factor that can be modified by environmental factors and is associated with more severe SLE clinical manifestations, which are related to deranged T cell function by downregulating the CD3zeta-chain.
ITAM sequence diversity is required for optimal TCR signal transduction and subsequent T cell maturation
Comprehensive Survey of miRNA-mRNA Interactions Reveals That Ccr7 (Montrer CCR7 Anticorps) and Cd247 (CD3 zeta) are Posttranscriptionally Controlled in Pancreas Infiltrating T Lymphocytes of Non-Obese Diabetic (NOD) Mice
There is an early (within seconds) interaction between CD3zeta and the coreceptor CD8 that is independent of the binding of CD8 to MHC.
The resting TCR localized in the disordered domain of giant plasma membrane (PM) vesicles (GPMVs) and PM spheres (PMSs) and single and nanoclustered TCRs are found in the high-density fractions in sucrose gradients.
When Ly108 (Montrer SLAMF6 Anticorps) is engaged in trans during cell-cell interactions, Ly108 (Montrer SLAMF6 Anticorps)-CD3zeta interactions are promoted in a manner that uniquely depends on Ly108 (Montrer SLAMF6 Anticorps) TM domain, leading to more efficient CD3zeta dephosphorylation.
Two transcription factor binding sites and a long non-coding RNA are identified within the Cd247 gene.
Zfat (Montrer ZFAT Anticorps)-deficiency results in a loss of CD3zeta phosphorylation with dysregulation of ERK (Montrer EPHB2 Anticorps) and Egr (Montrer EGR1 Anticorps) activities leading to impaired positive selection.
The results of this study supported the model that the procognitive function of CD3zeta may be mediated through its involvement in the NMDAR (Montrer GRIN1 Anticorps) downstream signaling pathway leading to CaMKII (Montrer CAMK2G Anticorps)-dependent LTP (Montrer SCP2 Anticorps) induction.
T cell CD3zeta deficiency enables multiorgan tissue inflammation.
Tyrosine phosphorylation of the TCR-zeta cytoplasmic domain regulates its association with the plasma membrane
The structure of the adaptor protein cd3zeta has been identified in the zebrafish genome.
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
CD247 antigen, zeta subunit
, CD3Z antigen, zeta polypeptide (TiT3 complex)
, CD3zeta chain
, T-cell antigen receptor complex, zeta subunit of CD3
, T-cell receptor T3 zeta chain
, T-cell surface glycoprotein CD3 zeta chain
, TCR zeta chain
, CD3 antigen, zeta polypeptide
, T-cell receptor T3 eta chain
, CD3 zeta
, CD247 molecule
, CD247 antigen
, T-cell receptor CD3 subunit zeta
, T-cell receptor CD3, subunit zeta
, CD3 zeta chain
, CD3 Zeta chain
, antigen CD3Z, zeta polypeptide
, T-cell receptor zeta chain