anti-Chien CD80 anticorps pour Immunoprecipitation

Recommended CD80 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
CD80 Anticorps
  • B7
  • B7-1
  • B7.1
  • BB1
  • CD28LG
  • CD28LG1
  • LAB7
  • B71
  • Cd28l
  • Ly-53
  • Ly53
  • MIC17
  • TSA1
  • CD80 molecule
  • Cd80 molecule
  • CD80 antigen
  • CD80
  • Cd80
Reactivité
Souris, Chien
456
285
49
11
10
6
3
3
2
2
1
Hôte
Hamster
399
126
97
93
42
16
Clonalité
Monoclonal
Conjugué
Cet anticorp CD80 est non-conjugé
71
70
53
40
19
17
16
15
10
7
7
6
6
6
6
6
6
6
6
5
5
5
5
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
508
220
171
153
114
101
81
42
39
26
22
21
12
8
8
6
6
5
5
5
2
2
2
2
1
1
1
1
Options
Fournisseur
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N° du produit ABIN489934
$ 261.86
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
13 ABIN1176972 BR IHC (fro) FACS IP Armenian Hamster IgG2, kappa Connectez-vous pour afficher 16-10A1 6
10 ABIN567985 Func IHC (fro) FACS IP Hamster IgG2 Connectez-vous pour afficher 16-10A1 9
10 ABIN2689407 BR IHC (fro) FACS IP Armenian Hamster IgG2, kappa Connectez-vous pour afficher 16 6
1 ABIN1821176 FACS IP IHC Hamster IgG Connectez-vous pour afficher G1-G1-4 0
1 ABIN1967873 BR FACS Func IHC IHC (fro) IP Neut Hamster IgG2 Connectez-vous pour afficher 16-10A1 0
1 ABIN3200026 FACS Func IHC (fro) IP Armenian Hamster IgG2 Connectez-vous pour afficher 16-10A1 0
1 ABIN3037606 FACS IHC IP Hamster IgG2 Connectez-vous pour afficher 0

General

Antigène CD80 Anticorps
Reactivité Souris, Chien
(456), (285), (49), (11), (10), (6), (3), (3), (2), (2), (1)
Hôte Hamster
(399), (126), (97), (93), (42), (16)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp CD80 est non-conjugé
(71), (70), (53), (40), (19), (17), (16), (15), (10), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6), (5), (5), (5), (5), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
(508), (220), (171), (153), (114), (101), (81), (42), (39), (26), (22), (21), (12), (8), (8), (6), (6), (5), (5), (5), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 8 références disponible
Fournisseur Connectez-vous pour afficher

Détail du produit anti-CD80 anticorps

Détail du antigène CD80 Information d'application Stockage References for anti-CD80 antibody (ABIN489934) Images
Specificité The Armenian hamster monoclonal antibody 16-10A1 reacts with CD80 (B7-1), a 60 kDa single chain type I glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.
Purification Purified from hybridoma culture supernatant by protein-A affinity chromatography.
Pureté > 95 % (by SDS-PAGE)
Immunogène CD80-transfected CHO cell line
Clone 16-10A1
Isotype IgG2
Plasmids, Primers & others

Détail du antigène CD80

Détail du produit anti-CD80 anticorps Information d'application Stockage References for anti-CD80 antibody (ABIN489934) Images Haut de la page
Antigène
Autre désignation CD80 (CD80 Antibody Extrait)
Sujet CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet, there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.
ID gène 12519
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process

Information d'application

Détail du produit anti-CD80 anticorps Détail du antigène CD80 Stockage References for anti-CD80 antibody (ABIN489934) Images Haut de la page
Indications d'application Flow Cytometry: Recommended dilution: 6 µg/mL
Functional Application: Blocking

Working concentrations should be determined by the investigator.
Restrictions For Research Use only

Stockage

Détail du produit anti-CD80 anticorps Détail du antigène CD80 Information d'application References for anti-CD80 antibody (ABIN489934) Images Haut de la page
Concentration 1 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do not freeze.
Stock 4 °C
Stockage commentaire Store at 2-8 °C. Do not use after expiration date stamped on vial label.

References for anti-CD80 antibody (ABIN489934)

Détail du produit anti-CD80 anticorps Détail du antigène CD80 Information d'application Stockage Images Haut de la page
Produit citée dans:

Mukherjee, Ahmed, Malu, Nandi: "Modulation of cell cycle progression by CTLA4-CD80/CD86 interactions on CD4+ T cells depends on strength of the CD3 signal: critical role for IL-2." dans: Journal of leukocyte biology, Vol. 80, Issue 1, pp. 66-74, 2006

Odobasic, Kitching, Semple, Timoshanko, Tipping, Holdsworth: "Glomerular expression of CD80 and CD86 is required for leukocyte accumulation and injury in crescentic glomerulonephritis." dans: Journal of the American Society of Nephrology : JASN, Vol. 16, Issue 7, pp. 2012-22, 2005

Paust, Lu, McCarty, Cantor: "Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 28, pp. 10398-403, 2004

Quah, Ni, ONeill: "In vitro hematopoiesis produces a distinct class of immature dendritic cells from spleen progenitors with limited T cell stimulation capacity." dans: International immunology, Vol. 16, Issue 4, pp. 567-77, 2004

Reiser, von Gersdorff, Loos, Oh, Asanuma, Giardino, Rastaldi, Calvaresi, Watanabe, Schwarz, Faul, Kretzler, Davidson, Sugimoto, Kalluri, Sharpe, Kreidberg, Mundel: "Induction of B7-1 in podocytes is associated with nephrotic syndrome." dans: The Journal of clinical investigation, Vol. 113, Issue 10, pp. 1390-7, 2004

Gueirard, Ave, Balazuc, Thiberge, Huerre, Milon, Guiso: "Bordetella bronchiseptica persists in the nasal cavities of mice and triggers early delivery of dendritic cells in the lymph nodes draining the lower and upper respiratory tract." dans: Infection and immunity, Vol. 71, Issue 7, pp. 4137-43, 2003

Mencacci, Montagnoli, Bacci, Cenci, Pitzurra, Spreca, Kopf, Sharpe, Romani: "CD80+Gr-1+ myeloid cells inhibit development of antifungal Th1 immunity in mice with candidiasis." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 6, pp. 3180-90, 2002

Horspool, Perrin, Woodcock, Cox, King, June, Harlan, St Louis, Lee: "Nucleic acid vaccine-induced immune responses require CD28 costimulation and are regulated by CTLA4." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 6, pp. 2706-14, 1998