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Aperçu des produits pour anti-CD86 (CD86) Anticorps

Full name:: anti-CD86 Molecule Anticorps (CD86)

Chez www.anticorps-enligne.fr sont 806 CD86 Molecule (CD86) Anticorps de 38 de différents fournisseurs disponibles. De plus, nous expédions CD86 Kits (70) et CD86 Protéines (53) et beaucoup plus de produits pour cette protéine. Un total de 950 CD86 produits sont actuellement listés.

Synonymes:: B7, B7-2, B7.2, B70, Cd28l2, CD28LG2, CLS1, ETC-1, LAB72, Ly-58, Ly58, MB7, MB7-2, TS/A-2

afficher tous les anticorps	Gène	GeneID	UniProt
	CD86	12524	P42082
	CD86	942	P42081
	CD86	56822
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Mouse (Murine) Monoclonal CD86 Primary Antibody pour BR, FM - ABIN1176959 : Borriello, Sethna, Boyd, Schweitzer, Tivol, Jacoby, Strom, Simpson, Freeman, Sharpe: B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation. dans Immunity 1997 (PubMed)
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Mouse (Murine) Monoclonal CD86 Primary Antibody pour IHC (fro), FACS - ABIN2689423 : Bluestone: New perspectives of CD28-B7-mediated T cell costimulation. dans Immunity 1995 (PubMed)
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Mouse (Murine) Monoclonal CD86 Primary Antibody pour BR, IHC (fro) - ABIN2689420 : Freeman, Borriello, Hodes, Reiser, Hathcock, Laszlo, McKnight, Kim, Du, Lombard: Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice. dans Science (New York, N.Y.) 1993 (PubMed)
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Mouse (Murine) Monoclonal CD86 Primary Antibody pour FACS - ABIN2689426 : Boussiotis, Gribben, Freeman, Nadler: Blockade of the CD28 co-stimulatory pathway: a means to induce tolerance. dans Current opinion in immunology 1995 (PubMed)
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Human Polyclonal CD86 Primary Antibody pour IF (p), IHC (p) - ABIN736701 : Evans, Jonason, Bussler, Torno, Veeraraghavan, Reilly, Doherty, Seils, Winter, Mallow, Kirk, Howell, Giralico, Scrivens, Klimatcheva, Fisher, Bowers, Paris, Smith, Zauderer: Antibody blockade of semaphorin 4D promotes immune infiltration into tumor and enhances response to other immunomodulatory therapies. dans Cancer immunology research 2015 (PubMed)
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Mouse (Murine) Monoclonal CD86 Primary Antibody pour FACS, Func - ABIN457341 : Radhakrishnan, Arneson, Upshaw, Howe, Felts, Colonna, Leibson, Rodriguez, Pease: TREM-2 mediated signaling induces antigen uptake and retention in mature myeloid dendritic cells. dans Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
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Mouse (Murine) Monoclonal CD86 Primary Antibody pour FACS, Func - ABIN457401 : Chung, Wells, Adler, Jacob, Turka, Monroe: Incomplete activation of CD4 T cells by antigen-presenting transitional immature B cells: implications for peripheral B and T cell responsiveness. dans Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
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Human Monoclonal CD86 Primary Antibody pour FACS, Func - ABIN301986 : Yadav, Judkowski, Flodstrom-Tullberg, Sterling, Redmond, Sherman, Sarvetnick: B7-2 (CD86) controls the priming of autoreactive CD4 T cell response against pancreatic islets. dans Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)
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Human Monoclonal CD86 Primary Antibody pour FACS, Func - ABIN302084 : Vasilevko, Ghochikyan, Holterman, Agadjanyan: CD80 (B7-1) and CD86 (B7-2) are functionally equivalent in the initiation and maintenance of CD4+ T-cell proliferation after activation with suboptimal doses of PHA. dans DNA and cell biology 2002 (PubMed)
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Mouse (Murine) Monoclonal CD86 Primary Antibody pour FACS, Func - ABIN457421 : Benschop, Melamed, Nemazee, Cambier: Distinct signal thresholds for the unique antigen receptor-linked gene expression programs in mature and immature B cells. dans The Journal of experimental medicine 1999 (PubMed)
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Plus d’anticorps contre CD86 partenaires d’interaction

Mouse (Murine) CD86 Molecule (CD86) interaction partners

Our results reveal a role for B7-2 as obligatory receptor for superantigens. B7-2 homodimer interface mimotopes prevent superantigen lethality by blocking the superantigen-host costimulatory receptor interaction.
results suggest that the TLR2-p38-CD86 signaling pathway plays a vital role in inflammation associated with burn injury
role with CD40 in primary germinal center generation of distinct antigen-presenting cells
The expression of CD1d showed a significantly negative correlation with CD86 level in B cells from imiquimod (IMQ)-treated mice, B6.MRLlpr mice, and lupus erythematosus (SLE) patients.
B7.2 expressed on skin CD8(+) T cells supports the survival of Tregs, likely through interaction with its receptor CTLA-4, which is highly expressed on skin Tregs.
CTLA-4(+) microvesicles can competitively bind B7 costimulatory molecules on bystander dendritic cells, resulting in downregulation of B7 surface expression.
Low CD86 expression is associated with B16 melanoma.
Local administration of CD86 siRNA during the effector phase ameliorates asthma phenotypes.
Meningococcal capsular polysaccharide-loaded vaccine nanoparticles induce expression of CD86.
The genetic inactivation of B7.1/B7.2 deteriorates obesity-related liver steatosis and metabolic dysregulation, likely a result of the intrinsic absence of Tregs in these mice, rendering DKO mice a novel murine model of NASH.
data show an important role of the adaptive immune system, in particular T cell CD80/86 costimulation molecules, in the physiological regulation of bone resorption and preservation of bone mass
CD80 and CD86 costimulatory molecules regulate OT-II CD4(+) T lymphocyte proliferation and cytokine response in cocultures with antigen-presenting cells derived from pregnant and pseudopregnant mice
novel function of CTLA4Ig in tumor immunity and suggest that CD86 on NK cells is an activating receptor and closely involved in the CTLA4Ig-mediated anti-tumor response.
The need for additional immune suppression in the intestine reflects commensal microbe-driven T-cell activation through the accessory costimulation molecules ICOSL and OX40L in B7 deprived mice.
CD4(+) NKG2D(+) T cells induce NKG2D down-regulation in natural killer cells in CD86-RAE-1epsilon transgenic mice.
CD86 expression has functional consequences for the magnitude of CD4 T cell responses both in vitro and in vivo. These data pinpoint CD86 upregulation as an additional mechanism by which IL-21 can elicit immunomodulatory effects.
B7.1 and B7.2 molecules have equal ability to mediate host resistance to Mycobacterium tuberculosis.
The activation of protective CD8 T cells requires positive B7-1/B7-2 costimulation even when suppression by Tregs and in particular, Treg-intrinsic CTLA-4 is circumvented.
the results presented here demonstrate that recruitment and expression of MHC-II, CD80, CD86, PDL1, and PD-L2 in M of peritoneal cavity in T. crassiceps early at infection is associated to the sex of the host.
Combinatorial signaling through TLR-2 and CD86 augments B-cell receptor-free activation and differentiation of resting B cells.

Human CD86 Molecule (CD86) interaction partners

CD86 gene rs1129055 and rs1915087 polymorphisms are significantly related to the risk of sepsis. For the rs1129055 polymorphism, the GA genotype and A allele are obviously correlated with increased risk of sepsis. Meanwhile, the carriers of the TT genotype and T allele of the rs1915087 polymorphism are more likely to develop sepsis.
Hepatitis C virus has a genetically determined lymphotropism through co-receptor B7.2.
this study shows that recipients' CD86 gene polymorphisms influence the overall survival after allogeneic hematopoietic stem cell transplantation and, together with CTLA-4 polymorphisms, might be considered a risk factor for acute graft versus host disease
results strongly suggest that CD40 and CD86 play a role in the pathophysiology of oral inflammatory diseases such as OLP
Our results reveal a role for B7-2 as obligatory receptor for superantigens. B7-2 homodimer interface mimotopes prevent superantigen lethality by blocking the superantigen-host costimulatory receptor interaction.
Our study reports a novel association of SNPs within CD86 and CTLA4 genes with pemphigus. The CD86 rs1129055 A allele appears to confer susceptibility to Pemphigus vulgaris but not to pemphigus foliaceus.
Our data demonstrate that CML patients with high CD86(+)pDC counts have a higher risk of relapse after TKI discontinuation.
The expression of CD1d showed a significantly negative correlation with CD86 level in B cells from imiquimod (IMQ)-treated mice, B6.MRLlpr mice, and lupus erythematosus (SLE) patients.
IL-6, DEC205, and CD86 can be predictive biomarkers for the respiratory and immune effects of ambient PM2.5.
the upregulation of CD86 but not CD80 and PD-L1 on CD68+ cells in the liver of HBV-infected patients, observed in our study, suggest that the profile of CD68+ cells does not support the induction of proper Th1 responses that are needed to clear HBV infection. This might provide an explanation for the absence of potent HBV-specific T cells during chronic HBV infection.
CD86 variants association with susceptibility to multiple sclerosis in Iranian population.
B-cells from patients tolerant to the graft maintained higher IL-10 production after CD40 ligation, which correlates with lower CD86 expression compared to patients with chronic rejection.
TLR2, TLR4 and CD86 gene polymorphisms are associated with Recurrent aphthous stomatitis.
The SNP CD40 -1C>T was associated with the IgG response against PvDBP, whereas IgG antibody titers against PvMSP-119 were influenced by the polymorphism CD86 +1057G>A.
PD-L1 expression and the PD-L1/CD86 ratio in CD14(++)CD16(+) monocytes were higher during chronic hepatitis C virus infection.
Data show that induction of CD86 antigen expression on monocytes by human beta Defensin-3 (hBD-3) is suppressed by P2X7 purinoceptor (P2X7R) antagonist.
analysis of the expression of TLR-9, CD86, and CD95 in circulating B cells of patients with chronic viral hepatitis B or C before and after antiviral therapy
Polymorphisms in CD86 gene have diverse effects on the pathogenesis of pneumonia-induced sepsis.
CD86 +1057G/A polymorphism may be not associated with the genetic susceptibility to chronic immune thrombocytopenia in a Chinese population.
CD86 polymorphisms are associated with susceptibility to pneumonia-induced sepsis and may affect gene expression in monocytes.

Pig (Porcine) CD86 Molecule (CD86) interaction partners

Reduced CD86 antigen is associated with melanoma.
The complete cDNA encoding CD86 molecule of miniature swine was cloned, sequenced and analyzed.

Cow (Bovine) CD86 Molecule (CD86) interaction partners

Northern analysis revealed CD80 and CD86 mRNAs in luteal tissue, with greatest steady-state concentrations at midcycle

CD86 profil antigène

Antigen Summary

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

Alternative names and synonyms associated with CD86

CD86 molecule (CD86) anticorps
CD86 antigen (Cd86) anticorps
CD86 molecule (Cd86) anticorps

B7 anticorps
B7-2 anticorps
B7.2 anticorps
B70 anticorps
Cd28l2 anticorps
CD28LG2 anticorps
CLS1 anticorps
ETC-1 anticorps
LAB72 anticorps
Ly-58 anticorps
Ly58 anticorps
MB7 anticorps
MB7-2 anticorps
TS/A-2 anticorps

Protein level used designations for anti-CD86 Molecule (CD86) Anticorps

CD86 antigen , T-lymphocyte activation antigen CD86 , activation B7-2 antigen , early T cell costimulatory molecule-1 , early T-cell costimulatory molecule 1 , B-lymphocyte activation antigen B7-2 , BU63 , CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) , CTLA-4 counter-receptor B7.2 , FUN-1 , cd86 antigen , membrane glycoprotein , B7-2 protein , co-stimulatory molecule B7-2 , costimulatory molecule , CD86/B7-2 costimulatory molecule , B7-1 costimulatory molecule

GENE ID	SPECIES
470900	Pan troglodytes
493704	Felis catus
714390	Macaca mulatta
12524	Mus musculus
942	Homo sapiens
56822	Rattus norvegicus
403764	Canis lupus familiaris
397441	Sus scrofa
414345	Bos taurus
100008999	Oryctolagus cuniculus
554318	Ovis aries

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