anti-Rat (Rattus) CREB1 anticorps pour Intracellular Staining

Recommended CREB1 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
CAMP Responsive Element Binding Protein 1 (CREB1) Anticorps
  • creb
  • CREB1
  • Creb1
  • CREB
  • 2310001E10Rik
  • 3526402H21Rik
  • AV083133
  • Creb
  • Creb-1
  • creb1
  • zgc:55598
  • cAMP responsive element binding protein 1
  • cAMP responsive element binding protein
  • cAMP responsive element binding protein 1 S homeolog
  • cAMP responsive element binding protein 1a
  • CREB1
  • creb1
  • CREB
  • Creb1
  • creb1.S
  • creb1a
Épitope
pSer133
138
38
37
37
22
20
16
15
15
9
8
7
7
6
6
5
5
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
546
327
297
41
38
38
36
30
27
26
19
17
15
7
7
7
2
1
1
1
1
Hôte
Souris
446
100
11
1
Clonalité
Monoclonal
Conjugué
Cet anticorp CREB1 est conjugé à/à la Alexa Fluor 647
20
17
15
8
7
6
6
5
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
Application
Intracellular Staining (ICS)
439
216
191
96
91
45
43
42
30
11
11
10
4
3
2
2
2
1
1
1
Options
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N° du produit ABIN1177048
Produit non disponible pour cette région.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN1177049 ICS Alexa Fluor 488 Mouse IgG1, kappa pSer133 Connectez-vous pour afficher J151-21 1
1 ABIN1177047 ICS PE Mouse IgG1, kappa pSer133 Connectez-vous pour afficher J151-21 1

General

Antigène CAMP Responsive Element Binding Protein 1 (CREB1) Anticorps
Épitope pSer133
(138), (38), (37), (37), (22), (20), (16), (15), (15), (9), (8), (7), (7), (6), (6), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain, Souris, Rat (Rattus)
(546), (327), (297), (41), (38), (38), (36), (30), (27), (26), (19), (17), (15), (7), (7), (7), (2), (1), (1), (1), (1)
Hôte Souris
(446), (100), (11), (1)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp CREB1 est conjugé à/à la Alexa Fluor 647
(20), (17), (15), (8), (7), (6), (6), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Intracellular Staining (ICS)
(439), (216), (191), (96), (91), (45), (43), (42), (30), (11), (11), (10), (4), (3), (2), (2), (2), (1), (1), (1)
Pubmed 1 référence disponible
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Détail du produit anti-CREB1 anticorps

Détail du antigène CREB1 Information d'application Stockage References for anti-CREB1 antibody (ABIN1177048) Images
Marque BD Phosflow™
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogène Phosphorylated Human CREB Peptide
Clone J151-21
Isotype IgG1, kappa

Détail du antigène CREB1

Détail du produit anti-CREB1 anticorps Information d'application Stockage References for anti-CREB1 antibody (ABIN1177048) Images Haut de la page
Antigène
Autre désignation CREB (CREB1 Antibody Extrait)
Sujet Transcription of various genes is regulated by the cyclic AMP (cAMP) signal transduction pathway through a family of cAMP Responsive Element (CRE)-Binding transcription factors that include CREB, CREM (CRE Modulator), and ATF-1 (Activating Transcription Factor 1). The genes for these transcription factors encode multiple isoforms that are created by alternative splicing, alternative initiation codons, and alternative intronic promoters. Homo- and heterodimers of these members of the basic domain-and-leucine zipper superfamily of proteins bind the palindromic TGACGTCA sequence of CRE. CREB is expressed in all somatic cells, and many different stimuli activate CREB by phosphorylation of its serine 133 (S133). The transcriptional activity and specificity of CREB are regulated by the signaling pathways initiated by the various stimuli. Transcriptional regulation by CREB family members has been implicated in many physiological responses to extracellular and environmental stimuli, such as memory, tissue growth and development, and homeostasis. The J151-21 monoclonal antibody recognizes the phosphorylated S133 of human CREB in addition to cross-reacting with S63 of human ATF-1.
Domaine de recherche Transcription Factors
Pathways Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation

Information d'application

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Stockage References for anti-CREB1 antibody (ABIN1177048) Images Haut de la page
Volume d'échantillon 20 μL
Restrictions For Research Use only

Stockage

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Information d'application References for anti-CREB1 antibody (ABIN1177048) Images Haut de la page
Format Liquid
Buffer Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The antibody was conjugated to Alexa Fluor® 647 under optimum conditions, and unreacted Alexa Fluor® 647 was removed.

References for anti-CREB1 antibody (ABIN1177048)

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Information d'application Stockage Images Haut de la page
Produit citée dans:

Shaywitz, Greenberg: "CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals." dans: Annual review of biochemistry, Vol. 68, Issue 2, pp. 821-61, 2000

Images

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Information d'application Stockage References for anti-CREB1 antibody (ABIN1177048) Haut de la page
Supplier Images
Flow Cytometry (FACS) image for anti-CAMP Responsive Element Binding Protein 1 (CREB1) (pSer133) antibody (Alexa Fluor 647) (ABIN1177048) anti-CAMP Responsive Element Binding Protein 1 (CREB1) (pSer133) antibody (Alexa Fluor 647)