Profil protéine

The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum\; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with ATF6B

• activating transcription factor 6 beta (ATF6B) anticorps
• cyclic AMP-dependent transcription factor ATF-6 beta (LOC745411) anticorps
• activating transcription factor 6 beta (Atf6b) anticorps

• AA617266 anticorps
• ATF6beta anticorps
• Creb-rp anticorps
• Crebl1 anticorps
• G13 anticorps

Protein level used designations for ATF6B

cAMP responsive element binding protein-like 1 , activating transcription factor 6 beta , cyclic AMP-dependent transcription factor ATF-6 beta , cyclic AMP-dependent transcription factor ATF-6 beta-like , ATF6-beta , Creb-related protein , cAMP response element-binding protein-related protein , cAMP-dependent transcription factor ATF-6 beta , cAMP-responsive element-binding protein-like 1 , protein G13 , cAMP responsive elment binding protein-like 1 , cAMP response element binding protein-related protein