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Human Polyclonal FTH1 Primary Antibody pour WB - ABIN515829
Kim, Moore, Fussenegger: Genetically programmed superparamagnetic behavior of mammalian cells. dans Journal of biotechnology 2012
Human Polyclonal FTH1 Primary Antibody pour IF (p), IHC (p) - ABIN759641
Zhang, Zhao, Chang, Zhang, Chu, Zhang, Liu, Guo, Wang, Gao, Zhang, Chu: Calcium channel blockers ameliorate iron overload-associated hepatic fibrosis by altering iron transport and stellate cell apoptosis. dans Toxicology and applied pharmacology 2016
Cow (Bovine) Polyclonal FTH1 Primary Antibody pour IHC, WB - ABIN2785803
Sammarco, Ditch, Banerjee, Grabczyk: Ferritin L and H subunits are differentially regulated on a post-transcriptional level. dans The Journal of biological chemistry 2008
Show all 2 Pubmed References
Fe mediated decrease of lateral root length and density is enhanced in fer1-3-4 triple mutant plants.
phosphate starvation response of AtFer1 is not linked to the iron status of plants and is specifically initiated by phosphate deficiency
Data indicate that steady-state mRNA abundance for three representative Fe homeostasis genes, IRT1 (Montrer PARP3 Anticorps), bHLH39, and FER1, oscillated in light/dark (LD) cycles or warm/cold environmental cycles.
Data show that a leaf glutathione concentration threshold between 10 and 50 nmol GSHg(-1) FW is required for full induction of AtFer1 gene expression in response to iron.
new regulatory pathway involved in plant response to oxidative stress was revealed using the iron-induced Arabidopsis ferritin (Montrer FTL Anticorps) AtFER1 as a model
Ferritin (Montrer FTL Anticorps) accumulation during infection of Arabidopsis by E. chrysanthemi is a basal defense mechanism which is mainly activated by bacterial siderophores.
The X-ray crystal structure of the apoferritin-SDS (Montrer SDS Anticorps) complex was determined at a resolution of 1.9 A and revealed that the SDS (Montrer SDS Anticorps) binds in an internal cavity that has previously been shown to recognize various general anesthetics. [apoferritin]
Transmission electron microscopy shows a clear selectivity of alkylated ferritin (Montrer FTL Anticorps) adsorption onto the PCL (Montrer PKD2L1 Anticorps) phase while wild ferritin (Montrer FTL Anticorps) predominantly adsorbs onto the PDTD phase.
Ferritin (Montrer FTL Anticorps) is considered the major iron storage protein which maintains a large iron core in its cavity and has ferroxidase (Montrer CP Anticorps) activity. (Review)
the absence of Mitochondrial ferritin (Montrer FTMT Anticorps), which is highly expressed in the heart, increases the sensitivity of mitochondria to cardiac injury via oxidative stress.
As previously reported, homozygous loss of the Fth allele on a wild-type Ftl (Montrer FTL Anticorps) background was embryonic lethal. expression of the H subunit can rescue the loss of the L subunit and that H ferritin homopolymers have the capacity to sequester iron in vivo
provide a new mechanism for selective autophagy of ferritin (Montrer FTL Anticorps) and reveal a previously unappreciated role for autophagy and NCOA4 (Montrer NCOA4 Anticorps) in the control of iron homeostasis in vivo
Our data show that ferritin H (Montrer FTMT Anticorps) is required for B and T cell survival by actively reducing the labile iron pool.
Ferritin H (Montrer FTMT Anticorps) deficiency in most cells of the forebrain including cells of the choroid plexus caused accumulation of cerebrospinal fluid in the lateral ventricles and the subarachnoid space
Mycobacterium avium infection induces H-ferritin expression in mouse primary macrophages by activating Toll-like receptor 2.
3-Hydroxybutyrate dehydrogenase (Montrer BDH1 Anticorps)-2 and ferritin-H (Montrer FTMT Anticorps) synergistically regulate intracellular iron.
Fth plays a critical protective role during acute kidney injury.
FtH provides metabolic adaptation to tissue Fe overload, conferring tolerance to malaria
Report in vivo magnetic resonance imaging of xenografted neuroblastoma (Montrer ARHGEF16 Anticorps) tumors using FTH1 reporter gene expression controlled by a tet-on switch.
The H-ferritin could bind up to 24 NCOA4 (Montrer NCOA4 Anticorps)(383-522) fragments forming highly stable and insoluble complexes. The binding was partially inhibited only by Fe(II) among the various divalent metal ions analyzed. The iron-dependent, highly-specific formation of the remarkably stable H-ferritin-NCOA4 (Montrer NCOA4 Anticorps) complex shown in this work may be important for the characterization of the mechanism of ferritinophagy.
Recombinant human H-chain ferritin (Montrer FTL Anticorps) nanocages were characterized by transmission electron microscopy and dynamic light scattering. These results indicate that H-chain ferritin (Montrer FTL Anticorps) is able to self-assemble into nanocages with a narrow size distribution.
Among myelodysplastic syndromes patients only, CD163 (Montrer CD163 Anticorps) + macrophage density and HO1 (Montrer HMOX1 Anticorps) and H-ferritin expression by CD163 (Montrer CD163 Anticorps) + macrophages increased in tandem with marrow iron. High HO1 (Montrer HMOX1 Anticorps) was significantly associated with shorter overall survival.
Low levels of FTH-positive tumor cells and microglia/macrophages were associated with poor survival in anaplastic astrocytomas, while high amounts of FTL (Montrer FTL Anticorps)-positive microglia/macrophages had a negative prognostic value
fumarate increases ferritin (Montrer FTL Anticorps) gene transcription by activating the NRF2 (Montrer GABPA Anticorps) (nuclear factor [erythroid-derived 2]-like 2) transcription factor.
there is no significant relationship between serum ferritin (Montrer FTL Anticorps) concentrations and depressive symptoms among Chinese adults.
Data suggest that, in homopolymeric H-subunit ferritin (Montrer FTL Anticorps) (HuHF), iron oxidation proceeds with a 2:1 Fe(II):O(2) stoichiometry at iron level of 2 Fe(II) atoms/H-subunit with generation of H2O2; L-subunit-rich heteropolymeric ferritin (Montrer FTL Anticorps) also facilitates iron oxidation at the ferroxidase (Montrer CP Anticorps) center and additionally promotes oxidation at the mineral surface once iron-binding capacity has been exceeded.
Elevated serum ferritin (Montrer FTL Anticorps) levels are associated with hematologic malignancies.
Ferritin light chain (Montrer FTL Anticorps) and ferritin heavy chain are required for the neural differentiation of bone marrow-derived mesenchymal stem cells under extremely low-frequency electromagnetic field.
ferritin heavy chain up-regulation may be mediated by activation of NF-kappaB (Montrer NFKB1 Anticorps) and that in turn this may be related to the resistance of bovine papillomavirus type-2 (BPV-2) infected urothelial cells to apoptosis.
This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
ferritin heavy chain
, ferritin, heavy polypeptide 1
, ferritin H subunit B
, ferritin heavy chain 1
, ferritin heavy chain B
, ferritin, heavy polypeptide 1 b
, ferritin H chain
, ferritin H subunit
, Ferritin H subunit
, cell proliferation-inducing gene 15 protein
, placenta immunoregulatory factor
, proliferation-inducing protein 15
, ferritin heavy-chain
, Ferritin subunit H
, ferritin heavy polypeptide 1
, ferritin, heavy polypeptide-like 17 like 5