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Human Polyclonal FTH1 Primary Antibody pour IF (p), IHC (p) - ABIN759641
Zhang, Zhao, Chang, Zhang, Chu, Zhang, Liu, Guo, Wang, Gao, Zhang, Chu: Calcium channel blockers ameliorate iron overload-associated hepatic fibrosis by altering iron transport and stellate cell apoptosis. dans Toxicology and applied pharmacology 2016
Human Polyclonal FTH1 Primary Antibody pour WB - ABIN515829
Kim, Moore, Fussenegger: Genetically programmed superparamagnetic behavior of mammalian cells. dans Journal of biotechnology 2012
Cow (Bovine) Polyclonal FTH1 Primary Antibody pour IHC, WB - ABIN2785803
Sammarco, Ditch, Banerjee, Grabczyk: Ferritin L and H subunits are differentially regulated on a post-transcriptional level. dans The Journal of biological chemistry 2008
Show all 2 Pubmed References
Human oligodendrocytes undergo apoptosis when exposed to Sema4A (Montrer Sema4a Anticorps) and take up H-ferritin for meeting iron requirements and that these functions are mediated via the Tim-1 (Montrer ARHGEF5 Anticorps) receptor. H-ferritin can block Sema4A (Montrer Sema4a Anticorps)-mediated cytotoxicity. Sema4A (Montrer Sema4a Anticorps) is detectable in the CSF (Montrer CSF2 Anticorps) of multiple sclerosis patients and HIV-seropositive persons and can induce oligodendrocyte cell death.
High serum ferritin (Montrer FTL Anticorps) (SF) and the overall survival of allogeneic hematopoietic SF was only significantly associated with prolonged RBC (Montrer CACNA1C Anticorps) transfusion dependence post-transplantation.
the role of FTH1 in the FIH (Montrer CASR Anticorps) control of HIF-1 (Montrer HIF1A Anticorps) activity, is reported.
CD16 (Montrer CD16 Anticorps) expression and morphological maturity of neutrophils are associated with higher iron ferritin (Montrer FTL Anticorps) levels in major beta-thalassemia.
Study demonstrate that the amounts of ferritin heavy subunit are inversely correlated, in K562 cells, to H19 (Montrer NCKAP1 Anticorps)/miR (Montrer MLXIP Anticorps)-675 levels, and that this phenomenon may be largely attributed to the increase in ROS (Montrer ROS1 Anticorps) production induced by the FHC silencing.
Findings indicate that induction of EMT (Montrer ITK Anticorps), increased migration and survival depend, in MCF-7 and H460 cells, on the release of FHC control on two pathways, namely the iron/ROS (Montrer ROS1 Anticorps) metabolism and CXCR4 (Montrer CXCR4 Anticorps)/CXCL12 (Montrer CXCL12 Anticorps) axis.
ferritin heavy chain has a role in ovarian cancer stem cell expansion and epithelial to mesenchymal transition
Report in vivo magnetic resonance imaging of xenografted neuroblastoma (Montrer ARHGEF16 Anticorps) tumors using FTH1 reporter gene expression controlled by a tet-on switch.
The H-ferritin could bind up to 24 NCOA4 (Montrer NCOA4 Anticorps)(383-522) fragments forming highly stable and insoluble complexes. The binding was partially inhibited only by Fe(II) among the various divalent metal ions analyzed. The iron-dependent, highly-specific formation of the remarkably stable H-ferritin-NCOA4 (Montrer NCOA4 Anticorps) complex shown in this work may be important for the characterization of the mechanism of ferritinophagy.
Recombinant human H-chain ferritin (Montrer FTL Anticorps) nanocages were characterized by transmission electron microscopy and dynamic light scattering. These results indicate that H-chain ferritin (Montrer FTL Anticorps) is able to self-assemble into nanocages with a narrow size distribution.
Ferritin H subunit gene is specifically expressed in melanophore precursor-derived white pigment cells
ferritin heavy chain up-regulation may be mediated by activation of NF-kappaB (Montrer NFKB1 Anticorps) and that in turn this may be related to the resistance of bovine papillomavirus type-2 (BPV-2) infected urothelial cells to apoptosis.
FtMt (Montrer FTMT Anticorps) overexpressing mice have no significant defects and the overexpression of FtMt (Montrer FTMT Anticorps) does not affect the regulation of iron metabolism significantly in transgenic mice.
Ferritin (Montrer FTL Anticorps) is considered the major iron storage protein which maintains a large iron core in its cavity and has ferroxidase (Montrer CP Anticorps) activity. (Review)
the absence of Mitochondrial ferritin (Montrer FTMT Anticorps), which is highly expressed in the heart, increases the sensitivity of mitochondria to cardiac injury via oxidative stress.
As previously reported, homozygous loss of the Fth allele on a wild-type Ftl (Montrer FTL Anticorps) background was embryonic lethal. expression of the H subunit can rescue the loss of the L subunit and that H ferritin homopolymers have the capacity to sequester iron in vivo
provide a new mechanism for selective autophagy of ferritin (Montrer FTL Anticorps) and reveal a previously unappreciated role for autophagy and NCOA4 (Montrer NCOA4 Anticorps) in the control of iron homeostasis in vivo
Our data show that ferritin H (Montrer FTMT Anticorps) is required for B and T cell survival by actively reducing the labile iron pool.
Ferritin H (Montrer FTMT Anticorps) deficiency in most cells of the forebrain including cells of the choroid plexus caused accumulation of cerebrospinal fluid in the lateral ventricles and the subarachnoid space
Mycobacterium avium infection induces H-ferritin expression in mouse primary macrophages by activating Toll-like receptor 2.
3-Hydroxybutyrate dehydrogenase (Montrer BDH1 Anticorps)-2 and ferritin-H (Montrer FTMT Anticorps) synergistically regulate intracellular iron.
Fth plays a critical protective role during acute kidney injury.
The X-ray crystal structure of the apoferritin-SDS (Montrer SDS Anticorps) complex was determined at a resolution of 1.9 A and revealed that the SDS (Montrer SDS Anticorps) binds in an internal cavity that has previously been shown to recognize various general anesthetics. [apoferritin]
This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
, cell proliferation-inducing gene 15 protein
, ferritin H subunit
, ferritin heavy chain
, placenta immunoregulatory factor
, proliferation-inducing protein 15
, ferritin H chain
, ferritin H subunit A
, ferritin heavy chain 2
, ferritin heavy chain A
, ferritin H subunit B
, ferritin heavy chain 1
, ferritin heavy chain B
, ferritin, heavy polypeptide 1 b
, ferritin heavy polypeptide 1
, ferritin heavy-chain
, Ferritin subunit H
, ferritin, heavy polypeptide 1
, Ferritin H subunit
, ferritin heavy chain 1 a