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Human S100A8 Protein expressed in Wheat germ - ABIN1319072
Maiseyeu, Badgeley, Kampfrath, Mihai, Deiuliis, Liu, Sun, Parthasarathy, Simon, Croce, Rajagopalan: In vivo targeting of inflammation-associated myeloid-related protein 8/14 via gadolinium immunonanoparticles. dans Arteriosclerosis, thrombosis, and vascular biology 2012
Show all 5 Pubmed References
Human S100A8 Protein expressed in Escherichia coli (E. coli) - ABIN2181719
Gruda, Ruggeberg, OSullivan, Guliashvili, Scheirer, Golobish, Capponi, Chan: Broad adsorption of sepsis-related PAMP and DAMP molecules, mycotoxins, and cytokines from whole blood using CytoSorb® sorbent porous polymer beads. dans PLoS ONE 2017
Mouse (Murine) S100A8 Protein expressed in Escherichia coli (E. coli) - ABIN5569738
Schneider, Schenone, Ferreira, Kramann, Joyce, Hartigan, Beier, Brümmendorf, Germing, Platzbecker, Büsche, Knüchel, Chen, Waters, Chen, Chu, Novina, Lindsley, Carr, Ebert: Rps14 haploinsufficiency causes a block in erythroid differentiation mediated by S100A8 and S100A9. dans Nature medicine 2016
the levels of S100A8 and S100A9 (Montrer S100A9 Protéines) in the sera, and calprotectin levels in the sera and urines of bladder cancer patients, were determined.
MRP-8/14 concentration increases in coronary artery blood in association with thrombus formation in acute coronary syndrome.
ANGPTL6 (Montrer ANGPTL6 Protéines), S100A8 and S100A9 (Montrer S100A9 Protéines) are overexpressed in skin of psoriasis patients versus zero expression in controls.
Elevated breast cancer cell and stromal S1008 protein expression are significant indicators of poorer outcomes in early stage breast cancer patients. Evaluation of S100A8 protein expression may provide additional prognostic information beyond traditional breast cancer prognostic biomarkers.
S100A8 was required for laser-induced new collagen synthesis in skin cells.
S100A8 methylation has a role in diagnosis and prognosis of hepatocellular carcinoma
This study demonstrated that S100A8 was detected in the serums of Alzheimer disease patients
Studies indicate S100A8 as the most overexpressed gene, and the cell cycle pathway as the most promising biomarker and therapeutic target for relapsed childhood B-acute lymphoblastic leukemia (B-ALL).
Low S100A8 expression is associated with head and neck neoplasms.
Report role of fecal calprotectin assay in the diagnosis and management of inflammatory bowel disease.
Data suggest that up-regulation of S100A8 and S100A9 (Montrer S100A9 Protéines) is a key component of early endometrial response to uterine involution in the post-partum period and to prevent chronic endometritis/uterine inflammation; up-regulation can be influenced by diet.
Study verified porcine calprotectin (S100A8/A9) expression at the protein level in multiple Haemophilus parasuis infected tissues and explored their molecular characterization.
Chronic Pseudomonas aeruginosa biofilm infection reduces murine S100A8/ S100A9 (Montrer S100A9 Protéines) expression and delays species-specific burn wound closure.
data suggest that S100A8/A9 acts directly on BV-2 microglial cells via binding to TLR4 (Montrer TLR4 Protéines) and RAGE (Montrer AGER Protéines) on the membrane and then stimulates the secretion of proinflammatory cytokines through ERK (Montrer EPHB2 Protéines) and JNK (Montrer MAPK8 Protéines)-mediated NF-kappaB (Montrer NFKB1 Protéines) activity in BV-2 microglial cells.
The results obtained in the present study demonstrate for the first time that S100A8 as well as MyD88 (Montrer MYD88 Protéines) and NF-B are activated by T3 and that these molecules are directly involved in the thyroid hormone (Montrer PTH Protéines)-induced cardiac hypertrophic response. These data suggest that one of the mechanisms underlying T3-dependent cardiac hypertrophy/failure may involve the activation of an inflammatory pathway.
Like S100A8, S100A9 (Montrer S100A9 Protéines) and S100A8/A9 reduced neutrophil influx in acute lung injury provoked by lipopolysaccharide (LPS (Montrer TLR4 Protéines)) challenge.
theses findings reveal unexpected gene expression differences between WT and KO mice at a young age (in the absence of physiological stress), and address the hypothesis that Mrp8 and Mrp14 (Montrer S100A9 Protéines) accumulation promotes age-related inflammation
S100A8 and S100A9 (Montrer S100A9 Protéines) aggravate Coxsackievirus B3-induced myocarditis and might serve as therapeutic targets in inflammatory cardiomyopathies.
Neutrophil-derived S100A8/A9 promotes thrombocytosis in diabetic mice
Perinatal alarmins S100A8 and S100A9 (Montrer S100A9 Protéines) specifically altered MyD88 (Montrer MYD88 Protéines)-dependent proinflammatory gene programs. S100 programming prevented hyperinflammatory responses without impairing pathogen defense. TRIF (Montrer RNF138 Protéines)-adaptor-dependent regulatory genes remained unaffected by perinatal S100 programming and responded strongly to lipopolysaccharide, but were barely expressed.
S100a8 upregulation triggers NF-kappaB (Montrer NFKB1 Protéines) signal pathway through RAGE (Montrer AGER Protéines) and TLR4 (Montrer TLR4 Protéines), in response to laser-induced dermis wound healing.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.
, S100 calcium-binding protein A8 (calgranulin A)
, calgranulin A
, calprotectin L1L subunit
, cystic fibrosis antigen
, leukocyte L1 complex light chain
, migration inhibitory factor-related protein 8
, protein S100-A8
, urinary stone protein band A
, S100 calcium binding protein A8 (calgranulin A)
, S100 calcium binding protein A8
, S100 calcium-binding protein A8
, neutrophil cytosolic 7 kDa protein
, chemotactic S100 protein
, chemotactic cytokine CP-10
, pro-inflammatory S100 cytokine
, macrophage migration inhibitory factor-related protein-8