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A model is developed whereby transferrin-binding protein (Montrer HSP90B1 Protéines) (Tbp (Montrer TBP Protéines))B delivers transferrin to TbpA (Montrer TTR Protéines), which completes the iron removal and transport process.
identified polymorphisms of transferrin on a panel of 10 different pig breeds.
Results indicate that transferrin (Tf) is an inducible immune effector molecule that may play an important role in pathogen clearance of insect innate immunity.
Histochemical staining with anti-Tf antibody and an N-acetylglucosamine-binding lectin suggests that brain-type Tf is secreted from choroid plexus, CSF (Montrer CSF2 Protéines)-producing tissue
Data suggest that serum levels of biomarkers of iron status (ferritin, transferrin, and hemoglobin) are positively associated with risk of hyperuricemia in Chinese adults.
Three single nucleotide polymorphisms associated with iron regulation were genotyped in multiple sclerosis : two in the human hereditary hemochromatosis protein (Montrer HFE Protéines) gene HFE (Montrer HFE Protéines): rs1800562 (C282Y mutation) and rs1799945 (H63D mutation), as well as the rs1049296 SNP in the transferrin gene (C2 mutation). We only observed a higher prevalence of TF-C2 in multiple sclerosis patients
Increased serum transferrin and ceruloplasmin (Montrer CP Protéines) turnover in diet-controlled patients with type 2 diabetes has been reported.
This work presents an HPLC analysis of carbohydrate-deficient transferrin.
Transferrin associated with Adenoid Cystic Carcinoma of Parotid Gland in immunohistochemical study, was found up-regulated in Pleomorphic Adenoma of the Parotid Gland.
The RNAi knock-down of Trypanosoma brucei GSK3beta reduced Tf endocytosis.
holotransferrin treatment to recombinant-TfR1 (Montrer TFRC Protéines) HepG2 cells did not elevate HAMP (Montrer HAMP Protéines) responses compared to untreated or wild-type cells. In
The subgroup of Parkinson's disease (PD) patients shows higher levels of CSF alpha-synuclein than the rest, indicating that PD includes two subgroups, which differ in levels of brain-type transferrin and alpha-synuclein. (Review)
In this technical note, the aberrant glycosylation profiles of transferrin glycoforms in congenital disorder of glycosylation patients are presented to shed light on the Mass Spectrometry of native transferrin and glycopeptides from the viewpoint of clinical glycoproteomics.
the value of transferrin receptors (TfRs)/cell reveals a 100-fold increase in the number of TfRs per bEnd3 cells compared to human umbilical vein cells.
Identification of multiple transferrin species in the spleen and serum from mice with collagen-induced arthritis which may reflect changes in transferrin glycosylation associated with disease activity: The role of CD38.
Transcytosis and brain uptake of transferrin-containing nanoparticles by tuning avidity to transferrin receptor.
Together, these data indicate that Lcn2 (Montrer LCN2 Protéines), in combination with transferrin, confines Klebsiella pneumoniae to the airways and prevents invasion into tissue containing the pulmonary vasculature.
Transferrin(hpx/hpx) Hemojuvelin (Montrer HFE2 Protéines)(+/+) and Transferrin(hpx/hpx) Hemojuvelin (Montrer HFE2 Protéines)(-/-) phenotypes did not differ markedly, but RBC (Montrer CACNA1C Protéines) transfusions increased hepcidin (Montrer HAMP Protéines) levels in Transferrin(hpx/hpx) Hemojuvelin (Montrer HFE2 Protéines)(+/+) but not Transferrin(hpx/hpx) Hemojuvelin (Montrer HFE2 Protéines)(-/-)mice.
These results indicate that CALM is required for erythroid maturation and transferrin internalization in mice.
Neurodegenerative conditions involving iron-mediated toxicity may be due to a failure of iron transport or storage mechanisms, rather than to the presence of high levels of non-transferrin-bound iron.
Apotransferrin mitigates the neurotoxicity of hemoglobin in a cell culture model of intracerebral hemorrhage.
Descibed is the 2.4 A structure of inhibitor of carbonic anhydrase from a pseudomerohedral twinned crystal: a member of the transferrin superfamily.
transferrin receptor 2 (Montrer TFR2 Protéines) and HFE (Montrer HFE Protéines) are involved in holotransferrin-dependent signaling for the regulation of furin (Montrer FURIN Protéines) which involved Erk (Montrer EPHB2 Protéines) phosphorylation. Furin (Montrer FURIN Protéines) in turn may control hepcidin (Montrer HAMP Protéines) expression.
transferrin mRNAs in zebrafish were first expressed at approximately 7 hours postfertilization (hpf) in the yolk syncytial layer and later in the liver rudiment (48 hpf) and in the esophagus transiently (72-96 hpf)
The zebrafish hypochromic anemia mutant, gavi, exhibits transferrin deficiency due to mutations in transferrin-a.Transferrin-a plays a critical role both in iron transport & in regulating hepcidin (Montrer HAMP Protéines) expression in zebrafish embryos.
This study showed that pronounced lung eosinophilia in horses can be transient, abate without specific treatment, and in this instance, lack correlation to upregulation of expression of either IL-4 (Montrer IL4 Protéines) or IL-5 (Montrer IL5 Protéines).
This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum.
beta-1 metal-binding globulin
, Beta-1-metal-binding globulin
, allergen Gal d III
, ovotransferrin BB type
, ovotransferrin BC type
, ovotransferrin CC type
, serum transferrin
, serotransferrin B
, hypotransferrinemia with hemochromatosis
, liver regeneration-related protein LRRG03
, transferrin 1
, transferrin precursor
, T-cell replacing factor
, eosinophil differentiation factor
, prepro-thyrotropin-releasing hormone
, pro-thyrotropin-releasing hormone
, thyrotropin releasing hormone
, STF I
, Serotransferrin I
, Siderophilin I
, serotransferrin I
, siderophilin I