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Human Polyclonal CFL1/2 Primary Antibody pour IHC - ABIN362442
Chen, Cizeau, Vande Velde, Park, Bozek, Bolton, Shi, Dubik, Greenberg: Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins. dans The Journal of biological chemistry 1999
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Human Polyclonal CFL1/2 Primary Antibody pour IF, IHC - ABIN363074
Arber, Barbayannis, Hanser, Schneider, Stanyon, Bernard, Caroni: Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase. dans Nature 1998
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Cofilin-1 (Montrer CFL1 Anticorps) plays a dominant role in angiotensin-(1-7)-induced G0/G1 arrest and autophagy to maintain cellular homeostasis in human aortic endothelial cells
NKCC1 (Montrer SLC12A2 Anticorps) not only controls cell volume and Cl- concentration, but it can also regulate the actin cytoskeleton through Cofilin 1 (Montrer CFL1 Anticorps).
The enhancement of cancer cells invasion is dependent on CFL1 (Montrer VPS72 Anticorps), a known regulator of invadopodia maturation.
The present study demonstrates that miR (Montrer MLXIP Anticorps)-145 plays an important role in inhibiting cell migration by directly targeting PAK4 (Montrer PAK4 Anticorps), and identifies miR (Montrer MLXIP Anticorps)-145-PAK4 (Montrer PAK4 Anticorps)-LIMK1 (Montrer LIMK1 Anticorps)-cofilin (Montrer CFL1 Anticorps) as a novel regulatory pathway that contributed to colorectal cancer metastasis.
D44 and RHOA (Montrer RHOA Anticorps) are required for CFL1 (Montrer VPS72 Anticorps) phosphorylation and cell migration induced by CD74 (Montrer CD74 Anticorps) in breast cancer cells.
Our results revealed that CKS1 (Montrer CKS1B Anticorps) is involved in normal glutamatergic synapse development and dendritic spine maturation in adult hippocampus through modulating p27 (Montrer PAK2 Anticorps) stability.
Our study indicates that Cofilin 1 (Montrer CFL1 Anticorps) holds an important position in the development and progression of human bladder cancer
Results suggest that the immune-complex (IC) of cofilin-1 (Montrer CFL1 Anticorps) in sera is a potentially attractive serum biomarker for the prognosis of pancreatic ductal adenocarcinoma (PDAC).
High cofilin (Montrer CFL1 Anticorps) expression is associated with adrenocortical tumor.
In advance urothelial cancer, overexpression of nuclear cofilin (Montrer CFL1 Anticorps) correlates with bladder cancer progression.
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
18 kDa phosphoprotein
, cofilin, non-muscle isoform