Aperçu des produits pour anti-Lipoic Acid Synthetase (LIAS) Anticorps

Full name:: anti-Lipoic Acid Synthetase Anticorps (LIAS)

Chez www.anticorps-enligne.fr sont 27 Lipoic Acid Synthetase (LIAS) Anticorps de 13 de différents fournisseurs disponibles. De plus, nous expédions Lipoic Acid Synthetase Protéines (11) et Lipoic Acid Synthetase Kits (7) et beaucoup plus de produits pour cette protéine. Un total de 49 Lipoic Acid Synthetase produits sont actuellement listés.

Synonymes:: 7a5ex, 2900022L22Rik, 4933425M12Rik, C77512, LAS, Lip-syn, LIP1, LS, mLip1, PDHLD, zgc:66080

afficher tous les anticorps	Gène	GeneID	UniProt
	LIAS	11019	O43766
	LIAS	79464	Q99M04
	LIAS	305348	Q5XIH4
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Pathways pertinentes pour anti-Lipoic Acid Synthetase Anticorps

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Plus d’anticorps contre Lipoic Acid Synthetase partenaires d’interaction

Human Lipoic Acid Synthetase (LIAS) interaction partners

this study used a bioinformatics approach to predict its structure. . A homology model for LIAS protein was generated using X-ray crystallographic structure of Thermosynechococcus elogatsu. The active site of LIAS protein was mapped and docked with S-Adenosyl Methionine
oxoglutarate dehydrogenase (OGDH) and lipoic acid synthase (LIAS), which when mutated stabilize HIF1alpha in a non-hydroxylated form.
heterozygous mutations (c.738-2A>G and c.929T>C (p.Met310Thr)) in LIAS.
Patients with LIAS nonketotic hyperglycinemia varied in disease severity and cortical involvement.
We identified the homozygous mutation c.746G>A (p.Arg249His) in LIAS in an individual with neonatal-onset epilepsy, muscular hypotonia, lactic acidosis, and elevated glycine concentration in plasma and urine
Lipoic acid synthetase deficiency results in an overall disturbance in the antioxidant defense network, leading to increased inflammation, insulin resistance, and mitochondrial dysfunction.

Mouse (Murine) Lipoic Acid Synthetase (LIAS) interaction partners

Decreased endogenous lipoic acid gene expression plays a role in development of diabetic atherosclerosis in ApoE deficient mice.
deficiency increases oxidative stress and accelerates the development of diabetic nephropathy
Lias deficiency enhances atherosclerosis in male mice, at least in part due to reduced antioxidant capacity
Development of homozygous embryos lacking Lias is retarded.
Enhanced neutrophil sequestration in the livers of Lias+/- mice was associated with increased hepatocyte injury and increased gene expression of growth-related oncogene, E-selectin, and VCAM-1 in the liver and/or lung.

Lipoic Acid Synthetase (LIAS) profil antigène

Antigen Summary

The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.

Alternative names and synonyms associated with Lipoic Acid Synthetase (LIAS)

lipoyl synthase, mitochondrial (LOC5571879) anticorps
lipoic acid synthetase (THAPSDRAFT_31845) anticorps
lipoic acid synthetase (THAPSDRAFT_31673) anticorps
lipoic acid synthetase (UREG_00501) anticorps
lipoyl synthase (LOAG_04019) anticorps
lipoic acid synthetase (TERG_02451) anticorps
lipoic acid synthetase (Tsp_01534) anticorps
lipoic acid synthetase (LIAS) anticorps
lipoic acid synthetase (Lias) anticorps
lipoic acid synthetase (lias) anticorps
lipoic acid synthetase S homeolog (lias.S) anticorps
Lipoyl synthase, mitochondrial (umc2251) anticorps

7a5ex anticorps
2900022L22Rik anticorps
4933425M12Rik anticorps
C77512 anticorps
LAS anticorps
Lip-syn anticorps
LIP1 anticorps
LS anticorps
mLip1 anticorps
PDHLD anticorps
zgc:66080 anticorps

Protein level used designations for LIAS

lipoic acid synthetase , lip-syn , lipoate synthase , lipoyl synthase, mitochondrial , LS , lipoic acid synthase , Lipoate synthase , Lipoic acid synthase , PCO124891 , PCO124891_ov , p-umc2251

GENE ID	SPECIES
5571879	Aedes aegypti
7452159	Thalassiosira pseudonana CCMP1335
7453454	Thalassiosira pseudonana CCMP1335
8437299	Uncinocarpus reesii 1704
9941423	Loa loa
10379120	Trichophyton rubrum CBS 118892
10911601	Trichinella spiralis
11019	Homo sapiens
79464	Mus musculus
305348	Rattus norvegicus
393528	Danio rerio
443960	Xenopus laevis
479108	Canis lupus familiaris
530865	Bos taurus
100279807	Zea mays

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