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CHMP2B anticorps (AA 31-120) (Cy5)

CHMP2B Reactivité: Souris WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy5
N° du produit ABIN1410784
  • Antigène Voir toutes CHMP2B Anticorps
    CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))
    Épitope
    • 14
    • 14
    • 9
    • 5
    • 3
    • 2
    • 1
    • 1
    AA 31-120
    Reactivité
    • 41
    • 31
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 51
    • 3
    • 2
    Lapin
    Clonalité
    • 52
    • 4
    Polyclonal
    Conjugué
    • 26
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CHMP2B est conjugé à/à la Cy5
    Application
    • 45
    • 21
    • 20
    • 13
    • 12
    • 7
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Souris
    Homologie
    Human,Rat,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CHMP2B
    Isotype
    IgG
    Top Product
    Discover our top product CHMP2B Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))
    Autre désignation
    CHMP2B (CHMP2B Produits)
    Synonymes
    anticorps ALS17, anticorps CHMP2.5, anticorps DMT1, anticorps VPS2-2, anticorps VPS2B, anticorps 1190006E07Rik, anticorps RGD1306781, anticorps chmp2b, anticorps chmp2bl, anticorps zgc:77025, anticorps si:ch211-224m9.5, anticorps CHMP2B, anticorps cg4618, anticorps chmp2.5, anticorps dmt1, anticorps vps2-2, anticorps vps2b, anticorps CHMP2b-B, anticorps chmp2b-a, anticorps chmp2b-b, anticorps charged multivesicular body protein 2B, anticorps charged multivesicular body protein 2Bb, anticorps charged multivesicular body protein 2Ba, anticorps charged multivesicular body protein 2B pseudogene, anticorps charged multivesicular body protein 2B S homeolog, anticorps charged multivesicular body protein 2B L homeolog, anticorps CHMP2B, anticorps Chmp2b, anticorps chmp2bb, anticorps chmp2ba, anticorps LOC747711, anticorps chmp2b.S, anticorps chmp2b.L
    Sujet

    Synonyms: Charged multivesicular body protein 2b, CHM2B_HUMAN, CHMP2.5, CHMP2b, Chromatin modying protein 2b, Chromatin-modying protein 2b, DMT1, hVps2-2, Vacuolar protein sorting 2-2, VPS2 homolog B, Vacuolar protein sorting-associated protein 2-2, Vps2-2, VPS2B.

    Background: The charged multivesicular body proteins, commonly designated CHMPs, belong to the vacuolar sorting protein family and function as chromatin-modifying proteins. CHMP1-6 are all components of ESCRT (endosomal sorting complex required for transport) I, II or III complexes. These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), and are also required for the formation of these bodies. CHMP2B, also known as CHMP2.5 or vacuolar protein-sorting-associated protein 2-2, is a 213 amino acid cytosolic protein. Widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta and leukocytes, CHMP2B associates directly with CHMP2A and vps4 for the disassembly of the ESCRT-III complex. Defects in the gene encoding CHMP2B have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3).

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