HDAC11 anticorps (AA 238-251)

N° du produit ABIN2668595

Cet anticorps anti-HDAC11 Polyclonal Lapin (ABIN2668595) détecte spécifiquement HDAC11 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour HDAC11 anticorps (AA 238-251) (ABIN2668595)

Antigène: HDAC11 (Histone Deacetylase 11 (HDAC11))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC11 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HDAC11 anticorps

Épitope: AA 238-251

Fonction: HDAC11 antibody (pAb)

Purification: Affinity Purified

Immunogène: This HDAC11 antibody was raised against a peptide corresponding to amino acid residues 238-251 of human HDAC11.

Isotype: IgG

Information d'application

Indications d'application: WB: 1 - 3 μg/mL dilution For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.1 % Tween 20 to all blocking solutions may also reduce background. Individual optimization may be required.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: PBS containing 0.2 % gelatin and 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: 4 °C,-20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Store at 4°C for short term. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur HDAC11

Antigène: HDAC11 (Histone Deacetylase 11 (HDAC11))

Autre désignation: HDAC11

Sujet: HDAC11 (Histone Deacetylase 11) is a member of the class IV mammalian histone deacetylases (HDACs) involved in regulating chromatin structure during transcription. These enzymes catalyze the removal of acetyl groups from lysine residues of histones and other cellular proteins. Lysine N-e-acetylation is a dynamic, reversible and tightly regulated protein and histone modification that plays a major role in regulation of gene expression in various cellular functions. It consists of the transfer of an acetyl moiety from an acetyl coenzyme A to the e-amino group of a lysine residue. In vivo, acetylation is controlled by the antagonistic activities of histone acetyltransferases (HATs) and histone deacetylases (HDACs). The HDACs are grouped into four classes, on the basis of similarity to yeast counterparts: HDAC class I (HDAC1, HDAC2, HDAC3 and HDAC8), class II (HDAC4, HDAC5, HDAC6, HDAC7, 9 and 10), class III (SIRT1-7) and class IV (HDAC11). In humans, expression of HDAC11 is limited to only a few organs, including brain, heart, muscle and kidney, suggesting an important role of HDAC11 in those tissues.

Poids moléculaire: 36 kDa

ID gène: 79885

NCBI Accession: NP_001129513